71 results about "Endoclip" patented technology

A polymer of hydrophobic monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains the polymer and another biocompatible polymer. The polymer or polymer blend and optionally a biobeneficial material and / or a bioactive agent can form a coating on an implantable device such as a drug delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

Implantable devices formed of or coated with a material that includes an amorphous poly(D,L-lactide) formed of a starting material such as meso-D,L-lactide are provided. The implantable device can be used for the treatment, mitigation, prevention, or inhibition of a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

The present invention comprises the provision and use of a novel endoscopic device which is capable of stabilizing, straightening, expanding and / or flattening the side wall of a body lumen and / or body cavity so as to better present the side wall tissue for examination and / or treatment during an endoscopic procedure. The present invention also comprises the provision and use of a novel endoscopic device capable of steadying and / or stabilizing the distal tips and / or working ends of instruments inserted into a body lumen and / or body cavity, whereby to facilitate the use of those instruments.

Provided herein is a PEA polymer blend and coatings or implantable devices formed therefrom. The PEA polymer blend is formed of a PEA polymer and a material capable of hydrogen bonding with the PEA. The PEA polymer blend can form a coating on an implantable device, one example of which is a stent. The coating can optionally include a biobeneficial material and / or optionally with a bioactive agent. The implantable device can be used to treat or prevent a disorder such as one of atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, and combinations thereof.

A prodrug comprising a heparin and a drug is provided. The prodrug can be used to form a coating on a medical device. The prodrug can also be used with a polymeric material to form a coating on a medical device. The polymeric material can be a hydrophobic polymer, a hydrophilic polymer, a non-fouling polymer, or combinations thereof. The medical device can be implanted in a human being for the treatment of a disease such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

The present invention comprises the provision and use of a novel endoscopic device which is capable of stabilizing, straightening, expanding and / or flattening the side wall of a body lumen and / or body cavity so as to better present the side wall tissue for examination and / or treatment during an endoscopic procedure. The present invention also comprises the provision and use of a novel endoscopic device capable of steadying and / or stabilizing the distal tips and / or working ends of instruments inserted into a body lumen and / or body cavity, whereby to facilitate the use of those instruments.

Provided herein is a copolymer that includes a soft block (A) that contains poly(ester amide) (PEA) and a hard block (B). The copolymer can be any of AB, ABA or BAB type block copolymers. By varying the relative amount of the PEA block and the hard block, one can obtain a copolymer with a Tg for mechanical integrity in drug-delivery stent applications. The copolymer can be used alone or optionally in combination with a biobeneficial material and / or a biocompatible polymer to form an implantable device or a coating on an implantable device. When the copolymer is used in combination with a biobeneficial material, the copolymer and the biobeneficial material can be co-deposited or applied in sequence during the coating process. A coating formed of the copolymer may also include a bioactive agent. The implantable device can be implanted in a patient to treat, prevent, or ameliorate a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, and / or tumor obstruction.

An endoscope particularly suited for endocranial procedures and a method of using the endoscope. In some examples the endoscope is rigid except for a bend / tilt portion near a distal end of a rigid tube that is inserted in a patient's cranium, which distal end is controlled in a degree and direction of tilt with a finger operated controller at the endoscope's handle. Some examples use telescoping tubes that allow customizing the endoscope size for specific procedures. A distal portion of the endoscope can be disposable, supplied in a sterile package for a single procedure, thus taking into account contamination dangers that are particularly high for intracranial and certain other interventions and the fact that it can be difficult or impossible to effectively autoclave heat-sensitive components of certain endoscopes or effectively sterilize them using other techniques.

An endoscope particularly suited for endocranial procedures and a method of using the endoscope. In some examples the endoscope is rigid except for a bend / tilt portion near a distal end of a rigid tube that is inserted in a patient's cranium, which distal end is controlled in a degree and direction of tilt with a finger operated controller at the endoscope's handle. Some examples use telescoping tubes that allow customizing the endoscope size for specific procedures. A distal portion of the endoscope can be disposable, supplied in a sterile package for a single procedure, thus taking into account contamination dangers that are particularly high for intracranial and certain other interventions and the fact that it can be difficult or impossible to effectively autoclave heat-sensitive components of certain endoscopes or effectively sterilize them using other techniques.

Provided herein is a copolymer that includes a soft block (A) and a hard block (B) comprising a tyrosine di-peptide. The copolymer can be any of AB, ABA or BAB type block copolymers. The soft block can include a PEA polymer. A coating formed of the copolymer may also include a bioactive agent. The implantable device can be implanted in a patient to treat, prevent, or ameliorate a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, and / or tumor obstruction.

A clip package comprises: a clip assembly including at least one endoscopic clip and at least one connection ring connected to the clip, the connection ring having at least one skirt portion that is allowed to expand radially outwards and stick out when in natural state free from external force and closes inwards when depressed radially inwards, a cylindrical case including an accommodation section for accommodating the clip assembly, the cylindrical case further including at least one opening in a position corresponding to the skirt portion of the connection ring, the opening being provided to maintain the skirt portion in natural state, and a cylindrical outer tube movably fitted over the outer periphery of the case and including at least one skirt closer for depressing and inwardly closing the skirt portion when the skirt closer is moved to a position opposite the opening.

A polymer of hydrophobic monomers and hydrophilic monomers is provided. It is also provided a polymer blend that contains the polymer and another biocompatible polymer. The polymer or polymer blend and optionally a biobeneficial material and / or a bioactive agent can form a coating on an implantable device such as a drug delivery stent. The implantable device can be used for treating or preventing a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, patent foramen ovale, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

The invention discloses an indented balloon for vascular calcification plaques, which comprises a balloon body used for expanding a vascular wall; a indentation structure which is mounted on the outer surface of the balloon body, wherein the indentation structure comprises at least one indentation filament body, and the at least one indentation filament body is spirally arranged on the balloon body in a sleeving mode in the axial direction of the balloon body; in the radial direction of the balloon body, the free end of at least one indented filament body is spine-shaped; and in an expansion state, the free end of the indentation filament body is in contact with the calcified plaque. When the balloon body is conveyed to a calcified plaque lesion position, the spiral indented filament bodies can form a sliding effect, and the balloon body is promoted to smoothly pass through the calcified lesion position. The indented filaments on the outer surface of the balloon body are spiral, so that overhigh tension cannot be locally formed, the risk of complications such as vascular interlayer and vascular perforation is reduced, and the safety is improved. In addition, the free ends of the indentation filament bodies can generate impact force on the calcified plaque, so that the calcified plaque forms cracks and is separated from the blood vessel wall, and therefore, the treatment effect of the calcified plaque is improved.

A biocompatible plasticizer useful for forming a coating composition with a biocompatible polymer is provided. The coating composition may also include a biobeneficial polymer and / or a bioactive agent. The coating composition can form a coating on an implantable device. The implantable device can be used to treat or prevent a disorder such as atherosclerosis, thrombosis, restenosis, hemorrhage, vascular dissection or perforation, vascular aneurysm, vulnerable plaque, chronic total occlusion, claudication, anastomotic proliferation for vein and artificial grafts, bile duct obstruction, ureter obstruction, tumor obstruction, or combinations thereof.

The invention discloses a vascular clamp used in a vascular surgery department. The vascular clamp comprises a clamp module, an adsorption module and an adjusting module, wherein the clamp module comprises a pressing button, a pressure cylinder, a pressure spring, a pressure conveying tube, an execution telescopic cylinder and an execution telescopic rod; the pressure cylinder is connected with the outer surface of the pressing button in a sliding manner; the pressure spring is arranged between the bottom of the pressing button and the bottom of the inner wall of the pressure cylinder; the execution telescopic cylinder communicates with a part below the pressure cylinder through the pressure conveying tube; and the execution telescopic rod is moveably connected with the inner wall of the execution telescopic cylinder. Due to adoption of the adjusting module, when one vascular clamp block is adjusted, the other vascular clamp block can be driven to move together, then the time for adjustment can be shortened, and furthermore, the use efficiency of the device can be improved; due to adoption of the adsorption module, a blood vessel can be well adhered to surfaces of a blood vessel clamp cylinder and blood vessel clamp blocks, so that the blood vessel can be prevented from dissociation by accident in the operation process of a doctor, and furthermore, the use security degree of the device can be increased.

This invention is directed to devices and methods for improving wound closures produced during endoscopic surgery. These methods are directed to delivering and applying a quantity of hemostatic agents in either powder, solid, liquid, or gel form onto an open wound produced e.g., by polyp removal, followed by the application of pressure. The method is implemented preferably using existing endoscopic equipment; however, modifications to existing endoscopic insertion tubes, application and tamping devices and endoscopic clips deployed from the distal end of the insertion tube during endoscopic surgery are also within the scope of this invention.

The invention provides a rapid bleeding arresting device for field first aid and a use method thereof. The rapid bleeding arresting device comprises an integrated manual suction apparatus (1) embeddedinto disposable running-fire titanium clamp forceps (2), wherein the integrated manual suction apparatus (1) is provided with an LED lamp holder (3) with a replaceable battery, and a titanium clamp (4) capable of firing a plurality of pieces in a running manner is arranged at a distal end; and the suction apparatus (1) is provided with an suction tube interface and can be connected with a split type negative-pressure suction bottle (5) with a flow rate controllable switch as required. The suction apparatus can be in linkage through manually operating forceps handles, thus, negative pressure is formed inside the suction apparatus to suck operative field hematocele, and a burst blood vessel is located rapidly. The forceps (2) are further provided with a safety switch, the safety switch is switched on when a bleeding point is exposed, and then, the titanium clamp (4) can be triggered to clamp the bleeding point to complete a bleeding arresting operation. The bleeding arresting device provided by the invention simultaneously has the functions of illuminating, sucking, clamping and arresting bleeding, so that the use is very convenient, an operator can simultaneously carry out operative field exposing, operative field hematocele sucking and bleeding arresting operations through simplex operation, and thus, the use is more convenient and quicker.

The invention discloses a degradable zinc alloy anastomotic apparatus and a preparation method thereof. The degradable zinc alloy anastomotic apparatus uses a degradable Zn-Li-Mn-Y alloy as a material, and the degradable Zn-Li-Mn-Y alloy includes the following components: 0-1 wt.% of Li, 0-1 wt.% of Mn and 0-1 wt.% of Y, without including 0, and the rest are Zn and unavoidable impurities. The degradable zinc alloy anastomotic apparatus includes any one of absorbable suture, medical zipper, anastomotic nail, anastomotic ring, anastomotic clip, anastomotic cannula or vascular clamp. The degradable zinc alloy anastomotic apparatus of the invention is excellent in mechanical properties, simple and convenient in operation, firm in anastomosis, capable of being decomposed in tissues or organs, capable of being fully absorbed by tissues and high in tissue compatibility.

A surgical device and tool for use in stabilizing tissue, such as an organ relative to a clamp, the surgical device having an elongate rigid member with a proximal end of the device having a stabilizing structure that rests against the skin of the subject and includes a vessel guide for guiding a blood vessel attached to the organ or tissue, and a distal end that mounts on the clamp. The surgical tool includes the combination of a clamp and the above-mentioned surgical device, with the clamp hingedly mounted on the distal end of the device. The tool is used to stabilize an organ by placement of the stabilizing structure against the skin of the subject, guiding a blood vessel with the vessel hook, and clamping such vessel distal to the vessel guide. A ligature is then placed across the vessel between the vessel guide and the clamp.

The invention discloses a multi-angle vascular anastomosis fixation device. The multi-angle vascular anastomosis fixation device comprises a device body; the device body is provided with a track; a first connecting rod and a second connecting rod are installed on the track in sequence; both the first connecting rod and the second connecting rod can slide on the track back and forth; the far end ofthe first connecting rod is hinged with a third connecting rod; the far end of the second connecting rod is hinged with a fourth connecting rod; the far end of the third connecting rod is connected to a first vascular clamp through a universal joint; and the far end of the fourth connecting rod is connected to a second vascular clamp through a universal joint. The multi-angle vascular anastomosisfixation device provided by the invention has the vascular clamps, which can slide on the linear track back and forth; a vascular wall can be pulled and fixed continuously and stably; the anterior and posterior walls of broken ends of blood vessels can be shown clearly; the proper vascular clamp can be selected and used according to a free blood vessel condition and its travelling angle; a support frame is arranged on the vascular clamp; the support frame has the function of opening a vessel cavity; endangium is not injured; multi-angle fixation also can be carried out; and in particular, thedevice can be used for pulling and fixing blood vessels travelling in different angles.

Medical devices and methods are disclosed for suturing tissue, that may be employed endoscopically and / or laparoscopically, and that offer simple, reliable and controllable placement of suture around a perforation for complete closure thereof. One embodiment of the medical system generally includes an endcap having first and second arms, a needle, a suture, and first and second control members. The first and second control members are used to pass the needle back-and-forth between the first and second arms.

The invention discloses a vascular clamp. The vascular clamp comprises a first supporting portion, a second supporting portion, a first operating portion, a second operating portion, a first clampingportion, a second clamping portion and a deformation portion, wherein the first supporting portion and the second supporting portion are arranged in a separated mode; the first operating portion extends upwards from the first end of the first supporting portion, and the second operating portion extends upwards from the first end of the second supporting portion; the first clamping portion extendsupwards from the second end of the first supporting portion, and the second clamping portion extends upwards from the second end of the second supporting portion; the distance between the first clamping portion and / or the second supporting portion and a middle vertical plane between the first supporting portion and the second supporting portion is gradually increased upwards from the first supporting portion or the second supporting portion; and the deformation portion is connected with an extending end of the first clamping portion and an extending end of the second clamping portion, and thedeformation portion can be deformed by operating the operating portions. When the vascular clamp is used, the gravity center of the vascular clamp is lower than that of a blood vessel, tissue damage caused by pulling and twisting can be reduced, and the vascular clamp is suitable in size and does not occupy the view during operation.

PROBLEM TO BE SOLVED: To easily constitute a high-frequency treatment instrument with a needle-shaped knife for efficient treatment of mucosal ablation and the like, and to ensure safety in treatment. SOLUTION: In the high-frequency treatment instrument, a hard chassis 20 is inserted / fixed to a chip of a flexible sheath 2. The hard chassis 20 comprises a through-hole 21 with a diameter larger than an outside diameter of a needle-shaped knife 13. A front end face 20a and a front end face 2a of the flexible sheath 2 constitute a circular end wall P in which their surfaces are approximately coincided with each other to make one flat surface. A rear end face 20b of the hard chassis 20 is a tapered face. The needle-shaped knife 13 comprises stopper projections 22, and a front end face 22a thereof is a slope face which can be fitted to the tapered face. Thereby the projecting length of the needle-shaped knife 13 is regulated, and a communicating way 24 is installed between the adjacent stopper projections 22, 22.

The invention relates to a blood vessel holder which comprises a holder body; the holder body is cylindrical; an elastic clamping piece is fixedly connected to the outer side wall of the holder body;and a clamping opening capable of clamping a blood vessel is formed by the holder body and the elastic clamping piece. The blood vessel holder can well clamp a bridge blood vessel, and is easy to control and small in damage to the blood vessel.

The invention discloses an emergency hemostasis method and an emergency hemostasis device for vascular surgery. The method is mainly realized by the following methods: determining a blood vessel that needs hemostasis, puncturing a blood vessel wall of the blood vessel from a bleeding site, sending an inflatable balloon matching a diameter of the blood vessel into the blood vessel, and blocking a blood flow channel inside the blood vessel through the inflatable balloon, so as to achieve a purpose of blood vessel hemostasis; withdrawing gas from the inflatable balloon and withdrawing the inflatable balloon from the blood vessel after surgery. The invention further discloses an emergency hemostasis device suitable for the emergency hemostasis method. The emergency hemostasis device comprises a pressing structure, a positioning structure, an air compression structure, an outer sleeve, a balloon gas injection pipe and an inflation balloon. The method and device can complete two actions of needle tip recovery and balloon inflation at the same time; are simple to operate, convenient and quick to use, have good hemostasis effect, and have little damage to blood vessels, are particularly suitable for patients whose blood vessels are fragile and cannot be stopped by clamping and compression methods such as vascular clamps, and are also particularly suitable for hemostasis in emergencies that occur during surgery.

An advanced polymeric, surgical clip is provided for clamping a blood vessel between two legs. A hook section of the clip comprises two sharpened forward edges for penetrating connective tissue adjacent a vessel before closing the surgical about a blood vessel. The upper leg of the surgical clip may comprise an oblique flank for disposing over the one or more edge of the hook section, the lower surface of the oblique flank defining a channel in which a tip of the hook section travels.

An advanced polymeric, surgical clip is provided for clamping a blood vessel between two legs. A hook section of the clip comprises two sharpened forward edges for penetrating connective tissue adjacent a vessel before closing the surgical about a blood vessel. The upper leg of the surgical dip may comprise an oblique flank for disposing over the one or more edge of the hook section, the lower surface of the oblique flank defining a channel in which a tip of the hook section travels.

To provide suction forceps for endoscopic surgery which are capable of quickly aspirating a fluid such as blood or another body fluid without requiring reinsertion of a dedicated aspiration tube even when there is leakage of blood or another body fluid during surgery, and consequently, also make it possible to prevent the duration of surgery from lengthening. Thus, suction forceps for endoscopic surgery are provided which are equipped with: a hollow section formed in a body section; a gripping part which manages tissue during surgery, and is formed at the tip end of the body section on one side thereof; and a suction port which is formed so as to be connected to the hollow section, and aspirates body fluid that has leaked from the tissue or blood that was effused during the surgery.

The invention provides a recyclable vascular interlayer plugging device. The recyclable vascular interlayer plugging device comprises a bare stent and a flow blocking film. The bare stent comprises a stent body and a recovery body; the support body comprises a support body section, a first turnover section and a second turnover section, wherein the first turnover section and the second turnover section are connected to the two ends of the support body section respectively, the recovery body is connected to one end of the support body section, and the first turnover section and the second turnover section both face the outer side of the support body section and overturn towards the recovery body; the flow blocking film covers the stent main body section, the first turnover section and the second turnover section; the first turnover section and the second turnover section are supported on the blood vessel wall in the circumferential direction and located on the two sides of a crevasse of the blood vessel interlayer respectively to block the crevasse, and the recovery body is used for recycling the recyclable blood vessel interlayer blocking device. The recyclable vascular interlayer plugging device provided by the invention can block blood flow of a true cavity and a false cavity and promote thrombosis of the false cavity, is particularly suitable for plugging a far-end crevasse of a vascular interlayer, and is wide in application range; and moreover, the device can be recycled and taken out, so that in-vivo implants and complications are reduced.