Therapeutic agent of peripheral blood flow disorder

A peripheral blood and disorder technology, applied in the field of cell preparations of pluripotent stem cells, can solve the problem of using Muse cells, etc., and achieve the effect of improving or restoring blood flow disorder and excellent safety.
CN113195054APending Publication Date: 2021-07-30KYOTO PREFECTURAL PUBLIC UNIV CORP

Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
KYOTO PREFECTURAL PUBLIC UNIV CORP
Publication Date
2021-07-30

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Abstract

Provided is a cell preparation for treating a peripheral blood flow disorder, the cell preparation including pluripotent stem cells (Muse cells) which are SSEA-3 positive and derived from mesenchymal tissues of a living body or cultured mesenchymal cells. The peripheral blood flow disorder is preferably a peripheral arterial disease, and more preferably, chronic arterial obstruction of the limbs.
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Description

technical field

[0001] The present invention relates to cell preparations in regenerative medicine. More specifically, the present invention relates to a cell preparation containing pluripotent stem cells effective for angiogenesis therapy of peripheral blood flow disorders such as peripheral arterial disease. Background technique

[0002] The proportion of the elderly population aged 65 and over is growing much faster than expected.

[0003] On the other hand, with the Westernization of eating habits and changes in lifestyles centered on a mobile society, new concepts of lifestyle-related diseases such as metabolic syndrome have emerged, and the disease structure of society has undergone tremendous changes. In particular, arteriosclerotic diseases and ischemic heart disease are increasing, and at the same time, peripheral arterial disease (PAD: peripheral arterial disease) is also increasing.

[0004] PAD mainly refers to chronic arterial occlusive disease of the extremit...

Claims

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