Preparation method of traditional Chinese medicine superfine powder decoction piece

Abstract

The invention discloses a preparation method of traditional Chinese medicine superfine powder decoction piece. The preparation method comprises the following steps: S1, cleaning and selecting: selecting traditional Chinese medicinal materials to be treated, removing mildewed products, non-medicinal parts and other impurities in the traditional Chinese medicinal materials, washing the traditional Chinese medicinal materials with water until the natural color of the traditional Chinese medicinal materials is seen, and airing moisture on the surfaces of the traditional Chinese medicinal materials; S2, coarse crushing: crushing the cleaned and selected traditional Chinese medicinal materials into medicinal material particles of 1.5-3mm by using a universal crusher; S3, crushing: adding 0.1-10 times (w / w) of water into the medicinal material particles obtained in the step 2, soaking to obtain a medicinal material particle suspension, and crushing the medicinal material particle suspension into uniform medicinal material slurry by adopting a colloid mill; S4, wall breaking: pumping the medicinal material pulp obtained in the step 3 into a heat preservation tank with a stirring function, starting stirring, raising the temperature of a jacket to 35-55 DEG C, and adding cellulase for enzymolysis wall breaking to obtain wall-broken medicinal material pulp;additives such as an anti-caking agent and a drying agent are not added in the preparation process, an organic solvent is not used, and the used cellulase is non-toxic and harmless protein, so that potential safety hazards cannot be brought to the product quality.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine processing, in particular to a preparation method of superfine powder decoction pieces of traditional Chinese medicine. Background technique [0002] The biologically active ingredients and effective ingredients in Chinese medicinal materials are the material basis for their prevention and treatment of diseases, but the operation process, absorption, metabolism, distribution and excretion of drugs by biological organisms are very complicated, and the pharmacological effects produced by traditional Chinese medicine preparations are still related to Its physical state is closely related, and changing the unit size of the drug powder is an effective method to change its physical state, so if the particle size of the drug powder can be reduced to the micron level or even to the nanometer level, then the The physical state of the drug will change significantly, which is mainly mani...

AI Technical Summary

Problems solved by technology

[0004] At present, the preparation methods of ultrafine powder decoction pieces of traditional Chinese medicine mainly include vibrating mill pulverization, mechanical pulverization, jet pulverization, etc., because the cell wall structure of Chinese medicinal plants is hard and strong, and the conventional pulverization method can make the pulverized drug powder particle size not greater than 45 μm, but This method has a limited effect on the fragmentation of the cell wall, so that the dissolution of effective substances in the cell is not ideal

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