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Pharmaceutical composition for treating cow mastitis and preparation

A composition and technology of mastitis, which are applied in the field of traditional Chinese medicine composition for treating cow mastitis and its preparation, can solve problems such as instructions for the treatment of cow mastitis, inflammation deterioration, and cow death during the milking period, and achieve reduction Adverse reactions of the body, cost saving, mild drug effect

Active Publication Date: 2022-03-04
LIAONING INST OF SCI & TECH +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the treatment of mastitis in lactating cows is not described
In addition, if the antibiotics are not selected properly during treatment, it will lead to worsening inflammation, mammary gland organic lesions, and even death of cows

Method used

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  • Pharmaceutical composition for treating cow mastitis and preparation
  • Pharmaceutical composition for treating cow mastitis and preparation
  • Pharmaceutical composition for treating cow mastitis and preparation

Examples

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Comparison scheme
Effect test

preparation example Construction

[0070] The pharmaceutical composition of the present invention can be prepared by conventional preparation methods of traditional Chinese medicine. For example, the preparation method of decoction includes: putting the above-mentioned raw materials of Chinese medicine (for example, in the form of decoction pieces) into a decoction container, and adding water to the decoction container until the raw materials of Chinese medicine are submerged, so that the medicine can completely absorb the water, and then decocted. Boiling, decocting for a predetermined time, filtering to prepare the medicinal composition as a decoction.

[0071] In an exemplary embodiment of the present invention, in the step of decocting for a predetermined time, the decoction container may be boiled on high heat and then decocted on low heat for 30 minutes.

[0072] The decoction for treating cow mastitis of the present invention can be obtained, for example, by the following method: put the raw material of ...

Embodiment 1

[0078] Embodiment 1: decoction treatment milk cow recessive mastitis

[0079] Chinese medicine raw materials: Bupleurum 10g, Scutellaria baicalensis 10g, Qingpi 20g, Chishao 10g, Wangbuliuxing 10g, Anemarrhena 10g, Astragalus 10g, Rehmannia 10g, Salvia miltiorrhiza 10g.

[0080] Preparation method: add to the decoction container, then add water until the above-mentioned traditional Chinese medicine raw materials are covered, soak for 30-60 minutes, turn on high heat and boil, then soak for 20 minutes, cool and filter to obtain decoction and medicinal residues, the decoction can be used for cows to drink.

[0081] Treatment and Treatment Effect Judgment

[0082] The criterion for judging the therapeutic effect is to use the California testing method (CMT method for short) to judge the course of dairy cow mastitis, negative (t) (somatic cell content in milk is less than 400,000 cell ml -1 ), doubtful (n), weakly positive (1), positive (2) and strongly positive (3). Each cow ...

Embodiment 2

[0083] Embodiment 2: powder treatment milk cow recessive mastitis

[0084] Chinese medicine raw materials: Bupleurum 30g, Scutellaria baicalensis 30g, Qingpi 30g, Chishao 10g, Wangbuliuxing 10g, Anemarrhena 30g, Astragalus 20g, Rehmannia 20g, Salvia miltiorrhiza 20g, Guizhi 1g, Asarum 1g, Fangfeng 1g, Duckweed 1g , 1g light tempeh, 1g mung bean, 1g Smilax, 1g myrrh, 1g holly and 1g Puhuang.

[0085] Preparation method: After being processed by the Chinese medicine raw material processing method described in the present invention, the Chinese medicine raw material is pulverized to 300 mesh, mixed, and set aside.

[0086] Treatment and Treatment Effect Judgment

[0087] Every cow takes a powder (about 220 grams / part) every day, and it is fed for 5 days. Go through the CMT method. The test results showed that after 3 days of treatment in the 10 cows treated, the number of somatic cells in the milk produced by 7 cows decreased to 400,000 cell ml -1 Next, observe the milk qua...

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Abstract

The invention provides a pharmaceutical composition and a preparation for treating cow mastitis. The pharmaceutical composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-40 parts of radix bupleuri, 10-40 parts of scutellaria baicalensis, 10-40 parts of pericarpium citri reticulatae viride, 10-50 parts of radix paeoniae rubra, 10-40 parts of cowherb seed, 10-40 parts of rhizoma anemarrhenae, 10-80 parts of astragalus membranaceus, 10-80 parts of radix rehmanniae and 10-40 parts of salvia miltiorrhiza. The pharmaceutical composition disclosed by the invention has the functions of soothing liver and regulating qi, promoting lactation and diminishing inflammation and the like, and can realize the effect of treating various types of cow mastitis. In addition, the feed is not suitable for cows in the gestation period, and has no obvious toxic and side effects on cows in other periods. In addition, the medicinal composition disclosed by the invention can be prepared into decoction or powder, and the cow mastitis can be well treated.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and more specifically, the invention relates to a traditional Chinese medicine composition for treating cow mastitis and a preparation method thereof. Background technique [0002] Cow mastitis is a common multiple disease worldwide, which is closely related to the feeding and environment of cows. Typically, the annual incidence of mastitis in dairy cows is 20% to 50% (Cynthia M. Kahn, ScottLine group [M]. China Agricultural Press, 2015). According to the statistics of the American Cow Mastitis Conference, the loss caused by cow mastitis accounts for about 1 / 3 of the total output value of the dairy industry, and the economic loss in the United States is about 2 billion US dollars every year. Cow mastitis is divided into dominant mastitis and recessive mastitis. Overt mastitis, mostly manifested as blockage and expansion of mammary ducts due to various reasons, plasma cells ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61K36/9068A61K9/08A61K9/14A61K9/48A61K9/20A61P15/14A61P31/04
CPCA61K36/233A61K36/539A61K36/752A61K36/71A61K36/65A61K36/36A61K36/8964A61K36/481A61K36/804A61K36/537A61K36/54A61K36/538A61K36/268A61K36/9068A61K36/238A61K36/232A61K36/605A61K36/88A61K36/48A61K36/90A61K36/896A61K36/236A61K36/258A61K36/486A61K36/328A61K36/185A61K9/0095A61K9/14A61K9/48A61K9/20A61K9/0056A61P15/14A61P31/04A61K2300/00
Inventor 王振宇王志学
Owner LIAONING INST OF SCI & TECH
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