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Calcium tablet special for women in lactation period and preparation method of calcium tablet

A technology for breastfeeding and women, which is applied in the field of special calcium tablets for breastfeeding women and its preparation, which can solve the problems of unreachable, negligible effect, calcium supplementation, etc.

Pending Publication Date: 2022-03-04
华子昂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These calcium supplement products are only designed from the perspective of calcium absorption, and none of them supplement calcium according to the physiological characteristics and molecular mechanism of postpartum women, and cannot fundamentally solve the calcium deficiency problem of postpartum women
The most suitable drug prescription was not screened from the molecular mechanism of postpartum osteoporosis, which lacked scientificity and effectiveness
[0005] In addition, the national food safety standard "Standards for the Use of Food Nutritional Fortifiers" (GB 14880—2012) stipulates that the amount of calcium added to beverages is 160 mg / kg - 1350 mg / kg. At present, the daily consumption of liquid foods related to calcium preparations in China About 100mL, the maximum amount of calcium added according to laws and regulations is only 135 mg, which is far below the daily calcium intake requirement of 1200-1500mg / day for postpartum women, and the effect of calcium supplementation on postpartum women is negligible. This problem also exists with kind food

Method used

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  • Calcium tablet special for women in lactation period and preparation method of calcium tablet
  • Calcium tablet special for women in lactation period and preparation method of calcium tablet
  • Calcium tablet special for women in lactation period and preparation method of calcium tablet

Examples

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Effect test

Embodiment 1

[0013] A special calcium tablet for breast-feeding women and its preparation method, the specific steps are as follows: S1 the following raw materials: 5 parts of yam, 2 parts of raspberry, 3 parts of Yizhi kernel, 2 parts of gorgon, 5 parts of red bean, and 5 parts of lily Finely pulverized and fully mixed; S2 stirring and leaching, the specific parameters are: 0.1M phosphate solution (pH7.0), liquid-solid ratio 5, extraction temperature 90°C, extraction time 0.5 hours, extraction times 2 times, microwave-assisted extraction Technology accelerates the dissolution, extraction uses a tubular centrifuge to obtain the supernatant, and the rotation speed is 16000 rpm to take the supernatant; after S3 supernatant is concentrated in vacuum, it is fully mixed with calcium carbonate micropowder containing 400mg of calcium; S4 is carried out according to the standard granulation process Granulation, aseptic processing, and preparation of calcium tablets for lactating women according to ...

Embodiment 2

[0015] A special calcium tablet for breast-feeding women and its preparation method, the specific steps are as follows: S1 the following raw materials: 30 parts of yam, 20 parts of raspberry, 20 parts of Yizhiren, 15 parts of gorgon, 40 parts of red bean and 30 parts of lily Mix after micro-grinding; S2 stirring extraction, the specific parameters are: 0.2M phosphate solution (pH7.0), liquid-solid ratio 12, extraction temperature boiling extraction, extraction time 2 hours, extraction times 1 time, using microwave-assisted extraction technology Accelerated dissolution, extraction using a tubular centrifuge to obtain the supernatant, the speed is 16000rpm to take the supernatant; S3 supernatant is concentrated in vacuum, mixed with calcium chloride containing 600mg calcium and calcium phosphate micropowder containing 200mg calcium; S4 press The standard granulation process is used for granulation, aseptic treatment, and the calcium tablets for lactating women are prepared accord...

Embodiment 3

[0017] A special calcium tablet for breast-feeding women and its preparation method, the specific steps are as follows: S1 the following raw materials: 10 parts of yam, 10 parts of raspberry, 10 parts of Yizhi kernel, 11 parts of Gorgon fruit, 10 parts of red bean and 10 parts of lily Mixing after micro-grinding; S2 stirring and extraction, the specific parameters are: pure water extraction, liquid-solid ratio 5, extraction temperature 90°C, extraction time 1 hour, extraction times 2 times, using microwave-assisted extraction technology to accelerate dissolution, extraction using tube type Centrifuge to obtain the supernatant, and take the supernatant at a speed of 16,000 rpm; S3 supernatant is concentrated in vacuum, and fully mixed with calcium carbonate containing 400 mg calcium and calcium phosphate micropowder containing 100 mg calcium; S4 is made according to the standard granulation process Calcium tablets for breastfeeding women were prepared according to the standard t...

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Abstract

Core gene targets of lactating female calcium deficiency are determined by life big data, a medicinal and edible plant formula for lactating female calcium supplement is obtained by screening by network pharmacological big data, and the medicinal and edible plant formula is prepared from the following raw materials in parts by weight: 5-30 parts of Chinese yam, 2-20 parts of raspberry, 3-20 parts of fructus alpiniae oxyphyllae, 2-15 parts of gordon euryale seed, 5-40 parts of phaseolus calcaratus and 5-30 parts of lily. The preparation method comprises the following steps: S1, carrying out superfine grinding on the Chinese yam, the raspberry, the fructus alpiniae oxyphyllae, the gordon euryale seed, the phaseolus calcaratus and the lily, carrying out wall breaking, and then extracting functional components; s2, centrifugally separating the extracting solution and taking supernatant; s3, concentrating the supernate, and mixing with the calcium raw material superfine powder; and S4, granulating, carrying out sterile treatment, and preparing the special calcium tablet for the women in the lactation period by a tabletting standard process. The calcium tablet is designed according to life big data, is prepared from medicinal and edible plant raw materials, and is simple in method.

Description

technical field [0001] The invention relates to a special calcium tablet for lactating women and a preparation method thereof. Background technique [0002] The substances needed for the growth of the fetus and newborn are provided by the mother, among which minerals such as calcium need to be provided by the mother. If calcium cannot be supplemented in time after delivery, it will not only affect the calcium content of milk and affect the development of newborns, but also easily lead to complications such as postpartum osteoporosis. [0003] At present, the most commonly used method of postpartum calcium supplementation is to take calcium supplement products. However, the current calcium supplement products are simply adding exogenous calcium (or adding vitamin D), and they are all calcium supplements for calcium supplementation. Source calcium and ignore other necessary conditions for calcium absorption, resulting in calcium absorption far below the daily requirement of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9062A61K9/20A61P3/14A61P15/00A61P19/10A61K33/06
CPCA61K33/06A61K36/8945A61K36/73A61K36/9062A61K36/62A61K36/48A61K36/8967A61K9/20A61P3/14A61P15/00A61P19/10A61K2236/331A61K2236/39A61K2300/00
Inventor 华子昂刘宝全朱美瑛孙宁竹添王姣万君兴
Owner 华子昂
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