Application of common turnip in resisting sleep deprivation injury
A technology of sleep deprivation and coriander root, which is applied in the application, medical preparations containing active ingredients, and the function of food ingredients, etc., can solve the problem of anti-sleep deprivation damage of coriander root extract, and achieve anti-sleep deprivation stress damage, Prevention and mitigation of sleep deprivation damage, effects of sleep deprivation stress damage
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Embodiment 1
[0036] Embodiment 1: the preparation of radish root water extract
[0037] The coriander root that the present invention adopts is planted in the eucalyptus in the east of the Qinghai-Tibet Plateau, with an average altitude of 4493.4m.
[0038] Cut coriander root into 3-5mm slices and air-dry in the shade for 2 weeks. According to the mass-volume ratio of coriander root and water as 1:8, heat to 100°C for reflux extraction for 2.5 hours, membrane filtration, and take the supernatant; repeat the extraction of the dregs once according to the above process to obtain the supernatant; The supernatants were combined and concentrated under reduced pressure until the solid content was 0.15 g / mL to obtain the root water extract, which was stored at -80°C for further experiments.
experiment example 1
[0039] Experimental example 1: Verification of anti-sleep deprivation injury of coriander root water extract
[0040] 1. Grouping of mice and their feeding conditions
[0041] The experiment was carried out after C57BL / 6J mice (22-25g) adapted to the experimental environment for one week. The animals were randomly divided into 6 groups (n=10): blank group (routine sleep), model group (SD), low-dose Diangen root group (1.0g / kg.bw.), middle-dose Diangen root group (2.0g / kg.bw. kg.bw.), coriander root high dose group (3.0g / kg.bw.), positive group (caffeine 10mg / kg.bw.). Dosage group is based on "Sichuan Provincial Tibetan Medicine Standards (2020)" (Sichuan Provincial Food and Drug Administration) in the conversion of the recommended dose (6g / d) for mice: the low dose of coriander root (equivalent to human 10 times the intake).
[0042] All experimental animal procedures were approved by the Ethics Committee of the Experimental Animal Center of Jiangnan University (application...
Embodiment 2
[0066] The composition of the present embodiment anti-sleep deprivation injury comprises 70 parts by weight of Radix Coriander root water extract, 30 parts by weight of Lycium barbarum water extract. The preparation method of coriander root water extract and wolfberry water extract is the same as in Example 1.
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