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Microwave ablation and carbonization component regulation and control method based on tissue temperature real-time feedback

A microwave ablation, real-time feedback technology, applied in microwave surgical instruments, surgical instrument parts, medical science and other directions, can solve problems such as hindering antenna heat conduction, bleeding, high fever, etc., to reduce carbonized components, improve quality of life, and expand effective range effect

Pending Publication Date: 2022-03-25
NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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Problems solved by technology

These carbonized components will hinder the heat conduction of the antenna, thereby limiting the area of ​​​​the solidification zone
In addition, in the process of microwave ablation of some organs such as the spleen, the extrusion and avulsion of the carbonized tissue on the surrounding tissue during the needle withdrawal process will cause bleeding, and the carbonized components will also cause side effects such as systemic inflammatory reactions and high fever.

Method used

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  • Microwave ablation and carbonization component regulation and control method based on tissue temperature real-time feedback
  • Microwave ablation and carbonization component regulation and control method based on tissue temperature real-time feedback
  • Microwave ablation and carbonization component regulation and control method based on tissue temperature real-time feedback

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Embodiment Construction

[0024] Such as figure 1 As shown, a microwave ablation carbonization composition control method based on real-time feedback of tissue temperature includes the following steps:

[0025] S1. Analyze the endothermic rate of the tissue sample by differential scanning calorimetry to obtain a DSC endothermic rate curve;

[0026] S2. According to the endothermic rate curve, obtain the temperature T corresponding to the maximum endothermic rate 1 , the T 1 and tissue carbonization temperature T 2 In comparison, set an appropriate upper temperature threshold T 3 and the lower threshold temperature T 4 ;

[0027] S3. Build a microwave ablation and real-time temperature monitoring system, set the ablation power P and time t, and obtain the temperature T at the energy radiation point of the ablation needle in real time;

[0028] S4. If T≥T 3 , pause the ablation, and record the ablation time t 1 , if T≤T 4 , continue to ablate, superimpose and record the ablation time t 1 , unti...

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Abstract

The invention discloses a microwave ablation and carbonization component regulation and control method based on tissue temperature real-time feedback, which comprises the following steps: S1, analyzing the heat absorption rate of a tissue sample through differential scanning calorimetry to obtain a DSC heat absorption rate curve; s2, acquiring a temperature T1 corresponding to the maximum heat absorption rate according to the heat absorption rate curve, comparing T1 with a tissue carbonization temperature T2, and setting a proper upper limit temperature threshold T3 and a proper lower limit temperature threshold T4; s3, a microwave ablation and real-time temperature monitoring system is built, ablation power P and time t are set, and the temperature T at the energy radiation point of the ablation needle is obtained in real time; s4, if T is larger than or equal to T3, ablating is paused, the ablating time t1 is recorded, if T is smaller than or equal to T4, ablating continues, the ablating time t1 is recorded in an overlapped mode, and ablating is ended until t1 is equal to t. According to the invention, an ablation area is closer to a sphere and is closer to a treatment target pursued by a clinician.

Description

technical field [0001] The invention relates to the technical field of microwave ablation therapy, in particular to a method for controlling carbonized components of microwave ablation based on real-time tissue temperature feedback. Background technique [0002] During microwave ablation, direct energy deposition within a limited range of action can lead to excessively high temperature in the tissue center around the microwave antenna, resulting in highly dry carbonized tissue. These carbonized components will hinder the heat conduction of the antenna, thereby limiting the area of ​​the solidification zone. In addition, during the microwave ablation of some organs such as the spleen, the extrusion and avulsion of the carbonized tissue on the surrounding tissue during the needle extraction process will cause bleeding, and the carbonized components will also cause side effects such as systemic inflammation and high fever. Contents of the invention [0003] The technical pro...

Claims

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Application Information

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IPC IPC(8): A61B18/18A61B18/00
CPCA61B18/1815A61B2018/00791A61B2018/00696A61B2018/00642A61B2018/00577
Inventor 钱志余晋晓飞冯宇钱露朱柔君吴鑫李梦雪李军乐
Owner NANJING UNIV OF AERONAUTICS & ASTRONAUTICS
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