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Micro-column gel card, sample adding mechanism and method

A micro-column gel card and gel column technology, which is applied in the field of medical devices, can solve problems such as slow detection speed, and achieve the effects of ensuring consistency, increasing the number of columns, and improving detection efficiency

Pending Publication Date: 2022-04-08
深圳市爱康生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The current micro-column gel cards generally have 6 or 8 columns, which are limited by the number of holes, and the detection speed is relatively slow when used with automatic instruments. Therefore, it is urgent to improve the micro-column gel cards. The detection efficiency of batch experiments does not affect the accuracy of detection results

Method used

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  • Micro-column gel card, sample adding mechanism and method
  • Micro-column gel card, sample adding mechanism and method
  • Micro-column gel card, sample adding mechanism and method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Such as Figure 1 to Figure 3 As shown, a micro-column gel card includes a fixed plate and some columns 3 arranged and fixed by the fixed plate, the plurality of columns are respectively fixed on both sides of the fixed plate, and the tubes on both sides of the fixed plate The columns are arranged in a dislocation manner, and any one of the tube columns 3 includes a sample loading chamber 301, a reaction chamber 302 and a gel column 303, the gel column 303 is used to load gel reagents, and the sample loading chamber 301 is arranged in the Above the gel column 303, the reaction chamber 302 is connected between the sample loading chamber 301 and the gel column 303, and the central axes of the sample loading chamber 301 and the gel column 303 do not coincide.

[0047] There is a certain dislocation relationship between the columns distributed on both sides of the fixed plate, and any two adjacent columns do not overlap, so as to ensure that the microcolumn gel card is used...

Embodiment 2

[0049] Such as figure 2 and Figure 4 As shown, in one embodiment, the number of columns on both sides of the fixed plate is equal and eight, forming a double-row sixteen-hole micro-column gel card. The columns on both sides of the fixed plate present a centrally symmetrical form, and the gel column The vertical projection of the sample chamber is internally tangent, and any two gel columns are parallel to each other and the front projections do not overlap. The column on the side of the fixed plate is set as the first column group ( Figure 4 The one in the upper row is the first pipe string group), and the pipe string on the other side is the second pipe string group ( Figure 4 Shown in the lower row is the first string group), such as Figure 4 As shown, the eight strings of the first string group are set to be H1~H8 respectively, and the eight strings of the second string group are set to be M1~M8 respectively, and the centers of any two adjacent strings distances are...

Embodiment 3

[0068] In this embodiment, the sample loading mechanism 5 has degrees of freedom of movement in X, Y, and Z directions, and the sample loading mechanism 5 includes four sample loading devices (such as Figure 6 The corresponding schematic diagram is shown, it should be noted that, Figure 6 It is a schematic diagram of the principle drawn to illustrate the technical effect of this embodiment, and does not represent the actual structural relationship), which are respectively the first sampling device 501, the second sampling device 502, the third sampling device 503 and the fourth sampling device 504, the distance between any two adjacent sampling devices is twice the center-to-center distance of adjacent columns, which is 2d, and the sampling mechanism should condense the double-row sixteen-hole microcolumn The method of adding samples to the plastic card is as follows: Figure 8 Shown:

[0069] S8: the sample loading mechanism moves to the top of the microcolumn gel card; ...

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Abstract

The invention discloses a microcolumn gel card and a sample adding mechanism and method.The microcolumn gel card comprises a fixing plate and a plurality of tubular columns arranged and fixed through the fixing plate, the tubular columns are fixed to the two sides of the fixing plate respectively, the tubular columns located on the two sides of the fixing plate are arranged in a staggered mode, and any tubular column comprises a sample adding cavity, a reaction cavity and a gel column; the gel column is used for loading a gel reagent, the central axis of the sample adding cavity and the central axis of the gel column do not coincide, the tubular columns are designed in a double-row staggered mode, compared with a single-row microcolumn gel card of the same type, the number of the tubular columns is increased through the design of the double-row tubular columns so that the detection efficiency can be multiplied, meanwhile, the staggered design of the double-row tubular columns can ensure that adjacent tubular columns do not overlap, and the detection accuracy is improved. And in addition, the eccentric design between the sample adding cavity and the gel column is adopted, so that the debugging of the sample adding position is facilitated.

Description

technical field [0001] The invention relates to the field of medical equipment, in particular to a microcolumn gel card, a sample loading mechanism and a method. Background technique [0002] Blood type detection technology has a history of more than 100 years, from the original slide method, paper method, test tube method and other classic methods, gradually developed to microtiter plate method, solid phase method, magnetized red blood cell method, and the gel that came out in 1990 Type detection method. [0003] The micro-column gel method is the recommended method for international safe blood transfusion inspection. The micro-column gel card is the core of the micro-column gel method. It is mainly used for blood type testing before surgery, blood transfusion, and neonatal hemolytic disease screening before pregnancy. The current new card detection method has replaced the traditional blood detection method and has become a new, more convenient, more stable and more accura...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N35/00G01N33/80
CPCB01L3/5023B01L2300/069B01L3/50857B01L2200/0631B01L2200/16B01L2400/0409B01L3/5021B01L3/5025B01L3/5085
Inventor 张传国赖鹏飞蔡晓祥王学琴郑凯
Owner 深圳市爱康生物科技股份有限公司
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