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Anti-allergic injection composition as well as preparation method and application thereof

A technology for injection and composition, which is applied in the field of anti-allergic injection composition and its preparation, can solve the problems of small clinical selection range for injection, long-term safety remains to be observed, short clinical use time, etc., and achieves significant therapeutic effect. , Enhance natural killer cell function, long-lasting anti-allergic effect

Inactive Publication Date: 2022-04-26
宁波市中医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, anti-allergic drugs are mainly for external use and oral administration, and the clinical selection range for injection is limited. Most of them are chlorpheniramine maleate injection, promethazine hydrochloride injection, and hormones. The inhibitory effect is obvious, and long-term application of hormones has certain adverse reactions, such as central obesity, full moon face, buffalo back, inducing or aggravating infection or spreading potential lesions in the body
The scope of clinical use is limited. In recent years, biologics injections such as dupilumab have shown significant curative effects, but are expensive, and the clinical use time is short. Long-term safety remains to be seen.

Method used

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  • Anti-allergic injection composition as well as preparation method and application thereof
  • Anti-allergic injection composition as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The chlorpheniramine maleate injection of 5 parts by weight, the vitamin B12 injection of 10 parts by weight, the lidocaine hydrochloride injection of 60 parts by weight and the BCG polysaccharide nucleic acid injection of 20 parts by weight are compatible and mixed at normal temperature Obtain the composition for injection.

Embodiment 2

[0024] 19 parts by weight of chlorpheniramine maleate injection, 1 part by weight of vitamin B12 injection, 40 parts by weight of lidocaine hydrochloride injection and 40 parts by weight of BCG polysaccharide nucleic acid injection are compatible and mixed at normal temperature Obtain the composition for injection.

Embodiment 3

[0026] 25 parts by weight of chlorpheniramine maleate injection, 2 parts by weight of vitamin B12 injection, 50 parts by weight of lidocaine hydrochloride injection and 24 parts by weight of BCG polysaccharide nucleic acid injection are compatible and mixed at normal temperature Obtain the composition for injection.

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PUM

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Abstract

The invention discloses an anti-allergic composition for injection as well as a preparation method and application thereof, and is characterized in that the anti-allergic composition for injection is prepared from the following components in parts by weight: 5-25 parts of chlorpheniramine maleate injection, 1-10 parts of vitamin B12 injection, 40-60 parts of lidocaine hydrochloride injection and 20-40 parts of bacillus calmette guerin polysaccharide nucleic acid injection. The preparation method comprises the following steps: taking a 5ml sterile syringe, respectively sucking the chlorpheniramine maleate injection, the vitamin B12 injection, the lidocaine hydrochloride injection and the BCG polysaccharide nucleic acid injection according to the components, and uniformly mixing to prepare the required anti-allergic injection composition. The traditional Chinese medicine composition has the advantages that acupuncture point injection anti-allergic treatment is carried out through compatibility of various medicines, the treatment is remarkable in a long-term clinical test, and few adverse reactions occur.

Description

technical field [0001] The invention relates to the technical field of injection compositions, in particular to an anti-allergic injection composition and its preparation method and application. Background technique [0002] With the development of science, the change of environment and the change of people's lifestyle, allergic diseases are on the rise year by year. According to the World Allergy Organization (WAO) statistics, the total incidence of allergic diseases in the world is as high as 22%. The World Health Organization (WHO) clearly pointed out: "Allergic diseases have become a global disease affecting human health in the 21st century." [0003] In medicine, an allergic reaction is defined as a special pathological immune response, which manifests itself in the appearance of a certain tissue or organ after the body receives a certain allergen through various channels such as inhalation, ingestion, injection or contact. Even a strong systemic reaction can cause var...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K9/08A61P17/00A61P37/08A61K31/167A61K31/4402A61K31/714
CPCA61K31/4402A61K31/714A61K31/167A61K31/715A61K9/08A61K9/0019A61P37/08A61P17/00A61K2300/00
Inventor 陈宁刚张恋鲁晏武叶静静胡致恺叶姝徐豪亮钱伟王慧
Owner 宁波市中医院