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A low-dose benzene occupational exposure assessment method and system

A low-dose, occupational technology, applied in the field of occupational health and occupational disease control, can solve the problems of inability to quantitatively evaluate the occupational exposure of benzene, and achieve the effect of convenient collection and short time consumption

Active Publication Date: 2022-06-24
天津渤化讯创科技有限公司 +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The present invention proposes a low-dose benzene occupational exposure assessment method and system, which solves the problem of being unable to quantitatively assess benzene occupational exposure

Method used

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  • A low-dose benzene occupational exposure assessment method and system
  • A low-dose benzene occupational exposure assessment method and system
  • A low-dose benzene occupational exposure assessment method and system

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0106] Embodiment 1. Internal exposure assessment based on PBPK model simulation results:

[0107] This embodiment is based on the above-mentioned first scenario, and the evaluation process includes:

[0108] S1: Shoe factories and basketball factories mostly use benzene-containing adhesives and treatment agents as chemical raw materials. In addition to benzene, the raw materials usually contain benzene-based compounds such as toluene and xylene. The benzene content was determined by solvent desorption-gas chromatography-mass spectrometry specified in GBZ / T 300.59-2017.

[0109] S2: Between 2017 and 2018, benzene exposure assessments were conducted on 38 benzene-exposed workers in a shoe factory in Shandong, China, and 60 benzene-exposed workers in a basketball factory. Select it as the key risk management object. The adhesives and treatment agents used for it were identified as volatile organic compounds with a benzene content (volume fraction) of more than 1%.

[0110] S3...

Embodiment 2

[0135] Example 2. Internal exposure assessment based on biological monitoring results:

[0136] This embodiment is based on the above-mentioned third scenario, and the method for obtaining the functional relationship by using other data in the steps uses the method content of the second scenario; the evaluation process described in this embodiment specifically includes:

[0137] S1: Determine the benzene content according to the material situation.

[0138] S2: According to the actual exposure assessment needs and the benzene content determined by S1, determine the benzene operation and key risk management objects, and identify the exposure routes including inhalation and percutaneous absorption;

[0139] S3: Identify the traced exposure biomarkers as phenylmercaptouric acid (S-PMA) and trans-trans-mucofuroic acid (tt-MA) in urine.

[0140] S4: The exposure route considers percutaneous absorption, and biological samples can be collected and measured: Based on the functional r...

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Abstract

The invention proposes a low-dose benzene occupational exposure assessment method and system; including determining benzene content; determining benzene operations and key risk management objects; determining contact biomarkers for low-dose benzene exposure tracking; and performing exposure assessment according to scenarios. The invention solves the problem of being unable to quantitatively evaluate low-dose occupational exposure to benzene, helps scientifically analyze the degree of benzene occupational hazards, and provides a basis for clarifying key control points and key control groups of benzene occupational disease hazards.

Description

technical field [0001] The invention belongs to the field of occupational health and occupational disease control, and particularly relates to a low-dose benzene occupational exposure assessment method and system. Background technique [0002] Benzene is a clear carcinogen and is classified as a Class I carcinogen. In domestic occupational health technical services and enterprise occupational health management, there are still many deficiencies in the assessment of benzene occupational exposure, especially low-dose benzene occupational exposure, which is embodied in the following problems: [0003] (1) At present, there is no clear basis for identifying benzene as an occupational disease hazard factor existing in the workplace, and under which circumstances it is necessary to conduct occupational disease hazard factor detection, occupational health inspection and occupational health management according to benzene operation; [0004] (2) Various industries that widely use b...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G16H50/30G16H50/70G01N33/50
CPCG16H50/30G16H50/70G01N33/50G01N2800/7028G01N2800/42G01N2800/50G01N2520/00
Inventor 李敏嫣黄德寅张倩陆婷婷王志东殷伊琳
Owner 天津渤化讯创科技有限公司
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