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Computation method and system for CT (Computed Tomography) angiography parameters

A technique of angiography and calculation method, applied in the field of medical diagnosis, to achieve the effect of reducing health hazards and allergy risks, reducing dependence, and using less dosage

Pending Publication Date: 2022-05-10
SHANGHAI PUTUO DISTRICT PEOPLES HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, there is no such method as described in this application that can quickly, accurately and automatically determine the delay time of CT angiography scanning and the amount of contrast agent used to obtain high-quality images, reduce the amount of contrast agent used, improve the utilization rate of contrast agent, and reduce the effect of CT angiography. Dependency on operator experience approach

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  • Computation method and system for CT (Computed Tomography) angiography parameters
  • Computation method and system for CT (Computed Tomography) angiography parameters
  • Computation method and system for CT (Computed Tomography) angiography parameters

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Embodiment 1

[0129] The inventors of the present application found in the clinical trials based on the low-dose method CT angiography technology that: when a sufficient amount of contrast agent (for example: 350mgI / ml specification contrast agent, inject 15-20ml contrast agent+normal saline 20 with the same flow rate, ~30ml) for the pre-test of contrast agent bolus injection, when the ROI in the blood vessel at the monitoring level is ideally located, the time-density curve (TDC) obtained will show a better linearity ( Figure 1-2 ), that is, the growth rate of the CT value measured at each sampling point after the slow growth period and before the peak value is basically stable with the decrease rate of each point before the peak value drops to the slow decline period, and the rising and falling curves are basically a linear function distribution, the average growth rate and average decline rate ( image 3 ). Combined with this finding, according to the analysis of the pharmacokinetic ch...

Embodiment 2

[0261] The computing system of CT angiography parameter of the present invention comprises:

[0262] The point collection unit is used to collect the peak point, at least one point on the ascending section, and at least one point on the descending section from the TDC curve of the bolus injection pre-test, and obtain the CT value and time corresponding to each point;

[0263] The calculation unit is used to collect the parameters according to the point collection unit, based on the theory: for a formal scan, if the contrast agent is continuously injected at the same flow rate as the bolus pre-test, the concentration of the contrast agent at a certain position in the blood vessel will appear The average rise rate and fall rate of CT value consistent with the low-dose test were calculated to obtain the delay time and contrast agent dosage required for the formal scan.

[0264] In a preferred example, the calculation system of the CT angiography parameters is also provided with a...

Embodiment 3

[0274] CT scanning system of the present invention comprises:

[0275] CT scan equipment, for obtaining CT scan images;

[0276] CT contrast agent, used to improve the visibility of CT scan images of target blood vessels;

[0277] The processor is used to execute the calculation method of the CT angiography parameters of the present invention, the calculation method includes: the time density curve of the region of interest obtained according to the pre-test of the contrast agent bolus injection, based on the theory: for the formal scan, as with If the contrast agent is continuously injected at the same flow rate as the bolus pre-test, the concentration of the contrast agent at a certain position in the blood vessel will show the same rising and falling rates of CT values ​​as in the small dose test, through the rise and fall of the time-density curve Calculate the rising rate and falling rate of CT value at the segmental sampling point, and combine the CT value and time of t...

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Abstract

The invention relates to a method and a system for calculating CT angiography parameters. The method comprises the following steps: according to a time density curve of a region of interest obtained by a contrast agent mass injection pre-test, on the basis of a theory: for formal scanning, if a contrast agent is continuously injected at the same flow speed as the mass injection pre-test, the concentration of the contrast agent at a certain position of a blood vessel can present a CT value rise rate and a CT value drop rate which are consistent with those in a small-dose test; the rising rate and the falling rate of the CT value are calculated at the rising section and the falling section of the time density curve, and by combining the CT value and the time of the sampling point and the CT value and the time of the peak point, the delay time and the contrast agent dosage required by keeping the CT value above the expected CT value within the formal scanning time of the region of interest are calculated. The system comprises a point acquisition unit and a calculation unit. The method can realize controllable image quality and expected scanning opportunity, can be widely used, realizes computer automation, is convenient to operate, and is safe and efficient in single-vessel or multi-vessel time-phase CT angiography.

Description

technical field [0001] The invention relates to the technical field of medical diagnosis, in particular to a calculation method and system for CT angiography parameters. Background technique [0002] CT angiography (CTA, CT angiography) has always been an important inspection method for diagnosing vascular diseases and has been widely used for many years. When the main body of the contrast agent bolus flows along the blood flow and passes through the area of ​​the blood vessel under examination, exposure scanning is performed to obtain a tomographic image of the target blood vessel filled with contrast agent, and then three-dimensional post-processing is performed to provide medical images and post-processing images of the blood vessels under examination. The current threshold method and low-dose CT angiography technology have been used for many years, and there are many sets of contrast agent schemes suitable for different angiographic CT angiography in the human body to me...

Claims

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Application Information

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IPC IPC(8): A61B6/03A61B6/00
CPCA61B6/032A61B6/481A61B6/504A61B6/488A61B6/5211A61B6/5294
Inventor 孙凯
Owner SHANGHAI PUTUO DISTRICT PEOPLES HOSPITAL