White titanium-free film coating material as well as preparation method and preparation application thereof

Abstract

The invention provides a white titanium-free film coating material as well as a preparation method and preparation application thereof, and the white titanium-free film coating material comprises the following raw materials in percentage by weight: 32-38% of food-grade calcium carbonate, 17-23% of hydroxypropyl methyl cellulose, 12-18% of maltodextrin, 12-18% of talcum powder, 7-13% of polyvinyl alcohol and 2-8% of polyethylene glycol. The white titanium-free film coating material is applied to medicine or food solid preparations. A white titanium-free film coating material is formed by mixing raw materials such as food-grade calcium carbonate, hydroxypropyl methyl cellulose, maltodextrin, talcum powder, polyvinyl alcohol and polyethylene glycol, a coating material containing second-class cancerogens such as titanium dioxide is replaced, various standards are met, and life health of people is guaranteed; by adjusting the weight percentage of each raw material, namely adopting 35% by weight of food-grade calcium carbonate, the final product has the same good covering rate as that brought by titanium dioxide, and also has good film-forming property and stability.

Description

【Technical field】 [0001] The present invention relates to a film coating material, particularly to a white titanium-free film coating material, a preparation method of a white titanium-free film coating material, a white titanium-free film coating material preparation application. 【Background】 [0002] In the production of pharmaceuticals and food solid preparations, in order to make them more stable, effective, convenient, cover up bitter and bad odors, and achieve sustained release, enteric-soluble and other purposes, it is necessary to wrap a suitable material on its surface, this process is called coating. The material wrapped up is called the coating material. [0003] Among them, film coating is widely used in tablets, pills, granules, capsules and other dosage forms because of its advantages such as no significant increase in tablet weight, easy operation, and does not affect disintegration time, while still having a good protective and stabilizing effect. [0004] Film co...

AI Technical Summary

Problems solved by technology

[0006] This regulation will be implemented on September 9, 2021, which limits the application of titanium dioxide in the pharmaceutical and food fields. At present, most European drug and food importers have required suppliers to provide tablet coatings that do not contain titanium dioxide.

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