Production device of lactonase

A production device and technology of lactonase, which is applied in the field of lactonase, can solve problems such as not easy to stir evenly, time-consuming and laborious, and difficult to clean the warehouse, so as to achieve the effects of enhancing stability, ensuring sealing, and improving cleaning effect

Active Publication Date: 2022-05-27
JIAOZUO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a production device of lactonase, which solves the problem that the production device of lactonase in the market in the prior art is affected by the characteristics of lactonase, is easily adsorbed on the inner wall of the chamber, and is not easy to stir evenly. At the same time, it also brings difficulty to the subsequent cleaning of the warehouse body. The cleaning process is time-consuming and laborious, which seriously delays the work efficiency of personnel.

Method used

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  • Production device of lactonase
  • Production device of lactonase
  • Production device of lactonase

Examples

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no. 1 example

[0030] refer to Figure 1-10 , a production device of lactonase, comprising a warehouse body 1, one side of the warehouse body 1 is provided with a controller, the controller electrically controls each electrical component, the upper surface of the warehouse body 1 is provided with a top cover 2, and the top cover A motor 8 is provided at the top center position of One end is provided with a round block 14, and the bottom of the round block 14 is provided with several stirring parts 15. The stirring parts 15 can not only stir the inside of the silo body 1, but also clean it to ensure the cleaning performance inside the silo body 1. .

[0031]The stirring part 15 includes a plurality of sets of horizontal frames 1511, one side of the horizontal frame 1511 is fixedly connected with the bottom of the round block 14, the other side of the horizontal frame 1511 is provided with an electromagnet 1510, and the bottom of the electromagnet 1510 is provided with a support rod 1501. A ...

no. 2 example

[0045] Based on the production device for lactonase provided by the first embodiment, in actual use, there are often lumpy reactants adhered to the inner wall or bottom of the chamber body 1, which not only reduces the quality of the reaction, but also affects the subsequent reactions. At the same time, because most of the existing adjacent brushes have a certain gap, it is impossible to stir and clean the reactants between the brush gaps, and there is a large block adhesion at the bottom of the silo body 1. Since the height of the bottom circular plate 18 and the bottom of the silo body 1 is constant, the large brush 19 cannot break the adhering objects when cleaning them, and long-term use will also cause the large brush 19 to deform, further reducing the Cleaning effect, in order to solve the above problems, the production device of the lactonase also has the following process in actual use.

[0046] When in use, the reactant is added to the interior of the bin body 1 along...

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Abstract

The invention relates to the technical field of lactonase, in particular to a lactonase production device which comprises a bin body, a controller is arranged on one side of the bin body, a top cover is arranged on the upper surface of the bin body, a motor is arranged in the center of the top of the top cover, and one side of the top of the top cover communicates with a feeding pipe; a round pipe penetrating through the top cover is arranged at the bottom of the motor, and a round block is arranged at the end, away from the motor, of the round pipe. Meanwhile, high-frequency irregular up-and-down movement of the main fixing blocks and the auxiliary fixing blocks on the outer surfaces of the supporting rods can be achieved through cooperation of the main fixing blocks and the auxiliary fixing blocks on the outer surfaces of the multiple sets of supporting rods, springs and a bottom-layer circular plate, the cleaning effect on the inner wall of the bin body is improved, then high-frequency impact is conducted on the bottom-layer circular plate, and the service life of the bin body is prolonged. And the bottom of the bin body is vibrated and cleaned in cooperation with a large brush, the cleaning effect is guaranteed, and the cleaning performance is improved.

Description

technical field [0001] The present invention relates to the technical field of lactonase, in particular to a production device of lactonase. Background technique [0002] Lactonase is an intermediate for the synthesis of useful substances such as pharmaceuticals, and it is necessary to produce γ-lactone derivatives such as optically active pantolactone at low cost in large quantities. [0003] The existing production device uses recombinant technology to introduce mature lactonase DNA and signal peptide region DNA into the host to produce γ-lactone derivatives that can selectively asymmetrically hydrolyze racemic pantolactone and the like. Lactonase, which can obtain stable activity that natural lactonase lacks, and can also obtain transformants that maintain high enzymatic activity and stably maintain this activity, and can effectively and industrially advantage asymmetric synthesis of γ-lactone derivatives thing. [0004] Chinese invention patent CN2009100456615 provides...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12M1/02C12M1/36C12M1/00
CPCC12M21/14C12M27/02C12M41/40C12M41/48
Inventor 李存红李艳粉徐燕郑丙利
Owner JIAOZUO UNIV
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