Differential mobility spectrometry and continuous sample injection ion trap mass spectrometry combined device and analysis method

Abstract

The invention discloses a differential mobility spectrometry and continuous sample injection ion trap mass spectrometry combined device and an analysis method thereof. The differential migration spectrum and the continuous sample injection ion trap mass spectrum are connected in series through a proper interface, and the differential migration spectrogram and the mass spectrogram of a detected sample are obtained in sequence under the same ionization source. Rapid screening of ions can be achieved by fixing the compensation voltage through the differential mobility spectrometry, it can be avoided that non-target ions enter an ion trap to cause coulomb effect and reduce mass spectrum sensitivity in a single-ion mode, and high-sensitivity monitoring of target substances is achieved. In a scanning mode, through dual qualitative analysis of the compensation voltage and the mass-to-charge ratio of a tested substance, the accuracy of sample analysis is greatly improved, and the application range of an instrument is expanded.

Description

technical field [0001] The invention relates to a combined device of differential mobility spectrometry and continuous sampling ion trap mass spectrometry and an analysis method thereof. The present patent discusses the composition, structure and usage of the device. The differential mobility spectrometer and ion trap mass spectrometer are connected in series through a specific interface, and the compensation voltage and mass-to-charge ratio of the substance are simultaneously characterized. Through the ion screening function of differential mobility spectrometry, the accuracy of the analysis and the sensitivity of the ion trap mass spectrometer are greatly improved. the scope of use of the instrument. Background technique [0002] Mass spectrometry is widely used in chemical analysis because of its high sensitivity, high selectivity, and ability to analyze most compounds. Among them, ion trap mass spectrometry is currently a research hotspot in the field of mass spectromet...

AI Technical Summary

Problems solved by technology

However, the device is highly specialized and is not suitable for untrained non-professionals, which limits its ability to be promoted on a large scale

[0005] Aiming at the problem that the above-mentioned device is highly specialized and unable to be popularized on a large scale, the present invention proposes a differential mobility spectrometry and ion trap mass spectrometry device and its analysis method. The device can work in two modes and has a high Detection Sensitivity and Qualitative Accuracy

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