Composition and granule for improving myelosuppression after chemotherapy and preparation method

A composition, the technology of epimedium, is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., and can solve the problem of expensive treatment

Active Publication Date: 2022-06-07
东莞市中医院
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] Aiming at the problem of high cost of treatment in the prior art for improving myelosuppression after chemotherapy, and the traditional Chinese medicine

Method used

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  • Composition and granule for improving myelosuppression after chemotherapy and preparation method
  • Composition and granule for improving myelosuppression after chemotherapy and preparation method
  • Composition and granule for improving myelosuppression after chemotherapy and preparation method

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Embodiment 1

[0030] A composition comprising 10 parts of Dodder, 10 parts of Epimedium, 10 parts of Ligustrum lucidum, 10 parts of Lycium barbarum, 20 parts of Astragalus, 10 parts of Atractylodes Rhizoma, and 15 parts of Sophora japonica. The above seven flavors were soaked in water for 30 minutes, decocted twice, the first decocted for 2 hours, the second decocted for 1 hour, combined the decoction, filtered, concentrated the filtrate, added an appropriate amount of dextrin and mixed well, dried and pulverized , add an appropriate amount of ethanol to make wet granules, dry, granulate, and make 1000g of granules, that is.

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Abstract

The invention provides a composition and granules for improving myelosuppression after chemotherapy and a preparation method, and relates to the field of traditional Chinese medicine, the composition comprises semen cuscutae, herba epimedii, glossy privet fruit, fructus lycii, radix astragali, rhizoma atractylodis macrocephalae and caulis spatholobi. The preparation method of the composition is simple, the effects of all the medicines can be fully exerted through compounding of the seven medicines, all the components interact and have a synergistic effect, osteogenic differentiation of bone marrow mesenchymal stem cells can be effectively promoted, hematopoiesis can be promoted, the hematopoietic microenvironment can be effectively improved, and therefore myelosuppression after chemotherapy can be improved.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a composition, granules and preparation method for improving bone marrow suppression after chemotherapy. Background technique [0002] Post-chemotherapy myelosuppression usually refers to the decline of bone marrow hematopoietic function, the decline of the activity of blood cell precursors in the bone marrow, and the reduction of peripheral blood three-lineage cells, especially the reduction of granulocytes. Myelosuppression delays the progress of chemotherapy, and may lead to serious complications and endanger life. The study of myelosuppression after chemotherapy has received extensive attention. At present, rhG-CSF (short-acting whitening agent for short) or PEG-rhG-CSF (long-acting whitening agent for short) is mostly used in clinic to treat myelosuppression after chemotherapy. Short-acting whitening agent or long-acting whitening agent have adverse reactions suc...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61K9/16A61P7/00A61P7/06
CPCA61K36/39A61K36/43A61K36/296A61K36/638A61K36/815A61K36/481A61K36/284A61K36/486A61K9/1652A61P7/00A61P7/06A61K2236/331A61K2236/39A61K2300/00Y02A50/30
Inventor 不公告发明人
Owner 东莞市中医院
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