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Chrysanthemum extract with contraceptive effect and plant contraceptive thereof

A chrysanthemum flower extract and extract technology are applied in the field of chrysanthemum flower extract and plant contraceptives, which can solve the problems of large side effects, female body side effects, inability to achieve contraceptive effect, etc., and achieve the effect of reducing endometrial thickness

Pending Publication Date: 2022-07-01
陈湘
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] At present, women in the world generally use contraceptives for contraception. Although there are many contraceptives that can be used, the current contraceptives all have relatively large side effects on women's bodies.
So far, the most commonly used contraceptives in Western medicine are oral estrogen, progesterone or a combination thereof. Most of them need to be taken every day for two weeks or even throughout the menstrual cycle. If you miss a dose, you may not be able to achieve the contraceptive effect, and side effects

Method used

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  • Chrysanthemum extract with contraceptive effect and plant contraceptive thereof
  • Chrysanthemum extract with contraceptive effect and plant contraceptive thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A chrysanthemum extract with contraceptive effect, the chrysanthemum extract is prepared by the following steps:

[0028] 1) Put chrysanthemum and pure water in an extraction tank according to the ratio of material to liquid of 30:1 ml / g, heat to boiling and then reduce the temperature to 80°C, keep slightly boiling for 2h, and then separate solid-liquid to obtain the crude extraction liquid;

[0029] 2) under the condition that the temperature is lower than 60 ℃, the extraction crude liquid is concentrated under reduced pressure to obtain the total chrysanthemum extract;

[0030] 3) The total extract is diluted with pure water, the macroporous resin is eluted for the first time to obtain the first eluate, the first eluate is concentrated to dryness, and the brown dry powder is obtained to obtain the extract 1; During the elution process, the concentration of the sample solution was 0.4 mg / mL, the macroporous resin was D101 macroporous adsorption resin, and the column w...

Embodiment 2

[0035] The plant contraceptive is prepared by dissolving the above chrysanthemum extract in physiological saline.

[0036] After drinking the above-mentioned plant contraceptives, within 1 day, the B-ultrasound found that the intima decreased from 11mm to 6mm.

[0037] like Figures 1 to 2 Shown: Endometrial cells were cultured in vitro, and the number of endometrial cells was significantly reduced after the addition of phytocontraceptives.

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Abstract

The invention discloses a chrysanthemum extract with contraceptive effect and a plant contraceptive thereof, and the method comprises the following steps: placing chrysanthemum and pure water in an extraction tank, heating to boiling, reducing the temperature to 75-85 DEG C, keeping slight boiling for 1-3 hours, and then carrying out solid-liquid separation to obtain an extraction crude liquid; concentrating under reduced pressure to obtain a total chrysanthemum extract; eluting the total chrysanthemum extract twice through macroporous resin to obtain a chrysanthemum extract; the plant contraceptive contains the chrysanthemum extract. After the chrysanthemum extract extracted by the invention is used for any day after menstruation is clean and before ovulation, the intimal thickness can be obviously reduced, and an effective contraception effect is achieved. The plant contraceptive disclosed by the invention only needs to be used for one day and cannot be missed; the beverage can be drunk after being dissolved in water, and is simple and convenient.

Description

technical field [0001] The invention relates to the technical field of contraceptives, in particular to a chrysanthemum extract with contraceptive effect and a plant contraceptive thereof. Background technique [0002] At present, women in the world generally use contraceptives for contraception. Although there are many contraceptives available, the current contraceptives all have major side effects on the female body. So far, the most commonly used contraceptives in Western medicine are oral preparations of estrogen, progesterone or their combination, most of which need to be taken for two weeks or even every day for the entire menstrual cycle. Side effects are greater. SUMMARY OF THE INVENTION [0003] The purpose of the present invention is to overcome the deficiencies of the prior art, and to provide a chrysanthemum extract with contraceptive effect and a plant contraceptive thereof. [0004] In order to achieve the above object, the present invention designs a chrys...

Claims

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Application Information

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IPC IPC(8): A61K36/287A61P15/18
CPCA61K36/287A61K9/0095A61P15/18A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2236/55
Inventor 邓斌温意曹丽娜罗建光
Owner 陈湘
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