Precise array electrical stimulation method for simulating peripheral nerve injury

Abstract

The invention relates to a precise array electrical stimulation method for simulating peripheral nerve injury. The method comprises the following steps: 1, constructing a forearm geometric model; 2, constructing a forearm electrical stimulation model, and designing electrode array distribution through finite element calculation: adding needle-shaped electrodes at two tail ends of the three-dimensional forearm geometric model, constructing a forearm electrode array electrical stimulation geometric model, and setting the conductivity of the forearm geometric model according to the electrical attributes of each tissue of the forearm and the electrical attributes of the needle-shaped electrodes; current stimulation is applied to the needle-shaped electrode, a forearm electrical stimulation model is constructed, a Maxwell equation is solved through finite element calculation, and electric field distribution of peripheral nerves of forearm tissue is obtained; the forearm nerve current density is calculated and used for evaluating the stimulation nerve electric quantity; a nerve fiber excitation function is calculated, and electrode array distribution including the number of needle electrodes, the distance between two needles and the included angle between the two needles is determined.

Description

technical field [0001] The invention belongs to the field of electrical stimulation methods for peripheral nerve injury, and in particular relates to a method for precise array electrical stimulation for simulating peripheral nerve injury. Background technique [0002] There are about 42,000-74,000 patients with peripheral nerve injury in the United States every year. Peripheral nerve injury leads to sensory and motor dysfunction, which seriously affects the quality of life of patients. Electrical stimulation is currently one of the most effective treatments to promote the recovery of peripheral nerve function. Koo, J found that electrical stimulation can promote the growth of proximal axonal buds after peripheral nerve injury, thereby promoting early functional recovery after peripheral nerve injury. Willand et al. further explored the mechanism and found that electrical stimulation at 20 Hz for 1 hour can promote the depolarization of the cell body of the proximal injured...

AI Technical Summary

Problems solved by technology

However, this method has the following disadvantages: 1. Acupuncture needles need to be specially modified, and the cost of acupuncture treatment is increased, which limits its popularization and application; 2. Acupuncture needles penetrate into acupoints near nerve damage, and there is a possibility of secondary nerve stabbing; 3. , This method only increases the conductivity of local electroacupuncture, and peripheral nerve damage often causes large-scale nerve changes, and it is difficult to meet the treatment needs by only increasing the depth of electroacupuncture

However, this study uses implantable microarray electrodes, which require surgical implantation, which has disadvantages such as high cost and high risk.

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