EPS composite acid for improving skin microbial barrier and preparation method of EPS composite acid

A technology for improving skin and microorganisms, which is applied in skin care preparations, pharmaceutical formulas, cosmetic preparations, etc. It can solve the problems of limited curative effect of photoaging skin, difficult control of exfoliation depth, and limited penetration depth, etc., to enhance skin barrier function Stable, good water retention and water retention ability, and the effect of maintaining the flora profile

Pending Publication Date: 2022-07-08
绽妍生物科技有限公司
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, mono-acid is used to repair the skin barrier, especially for the repair of the skin microbial barrier, and the single-acid peel has only the chemical and physical properties of one acid, and there are various defects and deficiencies, such as the peeling depth is not easy to control, After treatment, the skin is dry and irritated
Fruit acid skin peeling has uneven penetration, easy to over-penetrate, and must be neutralized by lye; salicylic acid skin peeling has limited penetration depth due to lipophilicity, and has limited curative effect on severe photoaging skin. prone to salicylic acid poisoning

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • EPS composite acid for improving skin microbial barrier and preparation method of EPS composite acid
  • EPS composite acid for improving skin microbial barrier and preparation method of EPS composite acid
  • EPS composite acid for improving skin microbial barrier and preparation method of EPS composite acid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 12 parts of lactobacillus exopolysaccharide extract, 10 parts of salicylic acid, 8 parts of octanoyl salicylic acid, 2 parts of citric acid, 3 parts of lactic acid, and mandelic acid 2 parts, 5 parts of glycolic acid, 3 parts of aldose acid, 2 parts of compound amino acid, 10 parts of dispersion liquid, 8 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 1:2:8 , histidine, D-methionine and hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26.

Embodiment 2

[0026] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 25 parts of lactic acid bacteria exopolysaccharide extract, 20 parts of salicylic acid, 12 parts of octanoyl salicylic acid, 8 parts of citric acid, 6 parts of lactic acid, and mandelic acid 7 parts, 10 parts of glycolic acid, 8 parts of aldose acid, 5 parts of compound amino acid, 40 parts of dispersion liquid, 25 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 3:5:8 , histidine, D-methionine and hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26.

Embodiment 3

[0028] An EPS composite acid for improving skin microbial barrier comprises the following raw materials in parts by weight: 20 parts of lactic acid bacteria exopolysaccharide extract, 15 parts of salicylic acid, 10 parts of octanoyl salicylic acid, 6 parts of citric acid, 4 parts of lactic acid, and mandelic acid 5 parts, 8 parts of glycolic acid, 5 parts of aldose acid, 3 parts of compound amino acid, 25 parts of dispersion liquid, 15 parts of emulsifier, the compound amino acid is composed of L-threonine with a mass ratio of 2:3:8 , histidine, D-methionine, hydroxyproline; the dispersion liquid is polycyanoacrylate n-butyl ester, and the emulsifier is PPG-26-butanol polyether-26;

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention provides EPS composite acid for improving skin microbial barrier and a preparation method thereof, and the EPS composite acid is prepared from the following raw materials in parts by weight: 12-25 parts of lactobacillus extracellular polysaccharide extract, 10-20 parts of salicylic acid, 8-12 parts of capryloyl salicylic acid, 2-8 parts of citric acid, 3-6 parts of lactic acid, 2-7 parts of mandelic acid, 5-10 parts of glycolic acid, 3-8 parts of aldose disaccharic acid, 2-5 parts of composite amino acid, 10-40 parts of dispersion liquid and 8-25 parts of emulsifier. Through mixing, scientific proportioning and synergistic effect of the compound acids, the skin barrier function can be recovered, the percutaneous moisture loss can be improved, the proportion of the compound amino acids can be adjusted, the skin can be protected, and the damage to the skin barrier can be reduced.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an EPS composite acid for improving skin microbial barrier and a preparation method thereof. Background technique [0002] The skin barrier is mainly composed of stratum corneum, structural lipids and skin lipid film, which protects various tissues and organs in the body from harmful external invasion and maintains the stability of the body's internal environment. Also included is the skin microbial barrier, which consists of the normal flora that colonizes the skin and mucosal surfaces. They can act as a barrier by competing with pathogens for binding epithelial cells and nutrients, or by secreting certain killing and bacteriostatic substances. The abnormal structure and function of the skin barrier are related to the etiology and pathological process of various skin diseases. Maintaining and repairing the skin barrier is of great significance to prevent bacterial invasion, r...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/368A61K8/365A61K8/44A61K8/49A61Q19/00
CPCA61K8/73A61K8/368A61K8/365A61K8/44A61K8/4946A61K8/4913A61Q19/00A61K2800/592A61K2800/5922A61K2800/85A61K2800/82Y02A50/30
Inventor 舒凌祖月榕
Owner 绽妍生物科技有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products