Sandalwood extract, sandalwood traditional Chinese medicine formula granules and preparation method thereof

A technology of extract and sandalwood, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. Guaranteed efficacy and good consistency

Active Publication Date: 2022-07-08
GUANGDONG YIFANG PHARMA
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The preparation method retains other heat-sensitive components in sandalwood, and can effectively save medicinal resources. The prepared sandalwood extract can be used to prepare sandalwood traditional Chinese medicine formula granules, which can ensure the content of volatile oil and ointment yield of sandalwood traditional Chinese medicine formula granules. The consistency of the standard decoction solves the problem that the existing sandalwood formula granules do not comply with the regulations

Method used

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  • Sandalwood extract, sandalwood traditional Chinese medicine formula granules and preparation method thereof
  • Sandalwood extract, sandalwood traditional Chinese medicine formula granules and preparation method thereof
  • Sandalwood extract, sandalwood traditional Chinese medicine formula granules and preparation method thereof

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preparation example Construction

[0058] The invention provides a preparation method of sandalwood extract, comprising the following steps:

[0059] Pretreatment: take sandalwood, pulverize it, pass through a 24-mesh sieve to 100-mesh sieve, and prepare decoction pieces of sandalwood;

[0060] Distillation extraction: by weight, take 10% to 50% of decoction pieces of sandalwood, add water, conduct steam distillation, and collect sandalwood volatile oil, aromatic water, distilled water solution and medicinal residues;

[0061] Decocting and extracting: take medicinal residues and the remaining sandalwood pieces, mix, add water to the obtained mixture for decocting, filter, and combine the decocting liquid with the distilled aqueous solution to prepare a sandalwood extract;

[0062] Concentration: the sandalwood extract is mixed with auxiliary material A, and concentrated to prepare sandalwood dry extract powder;

[0063] Inclusion and drying: mix aromatic water with β-cyclodextrin to prepare β-cyclodextrin sol...

Embodiment 1

[0133] The present embodiment provides a kind of sandalwood extract and its traditional Chinese medicine formula granules, and the preparation method is as follows:

[0134] (1) Take sandalwood medicinal materials, remove impurities, shred them first with a shredder equipped with a 1.5cm aperture screen, and then use a shredder equipped with a 1.0cm aperture screen to coarsely crush to obtain "coarse sandalwood particles". Take the coarse particles of sandalwood, pulverize them with a high-speed pulverizer, and pass through a 24-mesh sieve to obtain "Sandalwood Decoction Pieces".

[0135] (2) take an appropriate amount of sandalwood decoction pieces, take 10% of the batch of sandalwood decoction pieces, add 3 times the weight of water, carry out steam distillation for 3h, collect the distillate, the distilled water solution and the medicinal residue; let the distillate stand for 3h to carry out The layers were separated to obtain volatile oil and aromatic water.

[0136] (3) ...

Embodiment 2

[0146] The present embodiment provides a sandalwood extract and its traditional Chinese medicine granules. The difference between the preparation method of the present embodiment and the embodiment 1 is that in step (1), a 50-mesh sieve is passed.

[0147] The remaining step conditions of the preparation method of this example are the same as those of Example 1.

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Abstract

The invention relates to sandalwood extract, sandalwood traditional Chinese medicine formula granules and a preparation method thereof. The preparation method comprises the steps of pretreatment, distillation extraction, decoction extraction, concentration, inclusion and drying, and mixing to prepare the sandalwood extract. Wherein the specification of the sandalwood decoction pieces and the proportion of the sandalwood decoction pieces for distillation extraction are specifically limited. The sandalwood extract prepared by the method can be used for preparing sandalwood traditional Chinese medicine formula granules, the consistency of the volatile oil content and the paste yield of the sandalwood traditional Chinese medicine formula granules and standard decoction is ensured, and other heat-sensitive components in sandalwood are retained, so that the medicine effect is better ensured, aroma components in medicine residues are retained, and the curative effect is better. Medicinal resources are effectively saved, the prepared sandalwood traditional Chinese medicine formula granules can be well kept consistent with traditional sandalwood decoction piece water decoction, and the problem that existing sandalwood formula granules do not conform to laws and regulations is solved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine pharmacy, in particular to a sandalwood extract, sandalwood traditional Chinese medicine granules and a preparation method thereof. Background technique [0002] Sandalwood is the dry heartwood of the trunk of Santalum album L., a plant belonging to the family Sandalaceae. It has the functions of warming the air, appetizing and relieving pain. certificate. Clinically, sandalwood is mostly used in pound slices or sawed into small pieces, and then cut into small pieces and then decoction in decoction. Studies have shown that the medicinal components of sandalwood invigorating qi are volatile oil components, and the traditional decocting method is prone to the situation that the volatile oil components escape due to the long decoction time, so that the effect of sandalwood in “qi” cannot be fully exerted. In addition, decoction is time-consuming and labor-intensive, and the dec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61K9/16A61K47/69A61P1/00A61P1/08A61P9/10A61K135/00
CPCA61K36/185A61K47/6951A61K9/1652A61P9/10A61P1/00A61P1/08A61K2236/331A61K2236/51Y02A50/30
Inventor 崔婷孙冬梅徐杰邓桂海张志鹏李焐仪张正邓韬莫秋怡
Owner GUANGDONG YIFANG PHARMA
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