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Pharmaceutical composition for treating diabetic xerophthalmia

A technology for diabetic and dry eye syndrome, applied in the field of diabetes treatment, can solve the problems of artificial tears to treat the symptoms but not the root cause, and achieve the effect of improving symptoms

Pending Publication Date: 2022-07-29
银川市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, western medicine treatment is mainly to strictly control blood sugar and use artificial tears to relieve the symptoms of dry eye syndrome. However, artificial tears can only treat the symptoms but not the root cause, and need to be used every day. Once stopped, the symptoms of dry eye syndrome will reappear

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  • Pharmaceutical composition for treating diabetic xerophthalmia
  • Pharmaceutical composition for treating diabetic xerophthalmia
  • Pharmaceutical composition for treating diabetic xerophthalmia

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Embodiment Construction

[0012] The scheme of the present invention will be described in detail below in conjunction with the pharmacology of the drug.

[0013] King medicine: Coptis chinensis, chrysanthemum, mint, tribulus.

[0014] Rhizoma Coptidis purifies fire, detoxifies and dries dampness, clears stagnant heat in the stomach, and clears the fire of red eyes, swelling and pain. Modern pharmacological studies have confirmed that berberine in Coptis chinensis has a hypoglycemic effect better than metformin, and has a certain improvement effect on diabetic complications (cardiovascular, kidney, nerve damage). It can reduce the levels of serum CRP, IL-6 and TNF-α in type 2 diabetic rats, and has a strong inhibitory effect on acute inflammation and tissue metabolism. Many studies have shown that berberine in Coptis Rhizoma can resist oxidation, scavenge free radicals, and improve oxidation. Stress and the activity of cholinesterase, thereby preventing the process of cell dysfunction and apoptosis. Be...

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Abstract

The pharmaceutical composition for treating diabetic xerophthalmia comprises coptis chinensis, chrysanthemum, mint and tribulus terrestris. Chinese angelica, white peony root and nux prinsepiae; the invention also discloses a preparation method of the traditional Chinese medicine. Coptis chinensis, chrysanthemum, mint and tribulus terrestris are used as monarch drugs, and coptis chinensis and chrysanthemum remove stagnated fire of liver and stomach and clear heat of head and eyes; mint and tribulus terrestris clear liver and improve eyesight. Chinese angelica, white peony root and nux prinsepiae are used as ministerial drugs to nourish liver and benefit yin, activate blood and nourish blood to improve eyesight, and tonify eye orifices, Chinese wolfberry and dandelion are used as adjuvant drugs, Chinese wolfberry can tonify liver and kidney, replenish vital essence to improve eyesight, and dandelion can clear heat and subdue swelling. The medicines are combined to achieve the effects of clearing heat, drying dampness, activating and nourishing blood, replenishing vital essence and improving eyesight. After one or more courses of treatment, the symptom of xerophthalmia of a patient can be obviously improved, and the effect lasts for more than 2 months.

Description

technical field [0001] The present invention relates to the technical field of diabetes treatment, in particular to a pharmaceutical composition for treating diabetic dry eye. Background technique [0002] T2DM can cause a decrease in tear secretion and changes in tear film composition, resulting in a series of pathological changes such as decreased tear film stability, increased risk of inflammation, peripheral corneal neuropathy, and damage to meibomian gland function, resulting in the occurrence of dry eye. Diabetic dry eye syndrome is one of the chronic complications of diabetes, and its clinical manifestations are mostly dry eyes, foreign body sensation, burning sensation, itching sensation, photophobia, and blurred vision. When people have diabetes, the clinical manifestations of dry eye are more severe than those with dry eye alone, and blood sugar is more difficult to control. According to statistics, the incidence of diabetic dry eye is increasing year by year, wit...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P3/10A61P27/02
CPCA61K36/718A61K36/287A61K36/534A61K36/185A61K36/232A61K36/71A61K36/65A61K36/73A61K36/815A61K36/288A61P3/10A61P27/02A61K2300/00
Inventor 党毓起颜青董慧杰张敏赵智龙孙小惠汪燕燕党翔宋丽田强董朝侠杨青张琳婷于盛卫
Owner 银川市中医医院