Application of surazil lactone in preparation of tumor immune drug, tumor immune drug and composition
An immunological composition and immunological drug technology, applied in the field of tumor immunological drugs and compositions, can solve the problems of small effect and the like
Pending Publication Date: 2022-08-09
SHANXI UNIV OF CHINESE MEDICINE
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- Abstract
- Description
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Problems solved by technology
However, not all of the drugs capable of activating immune cells disclosed in the prior art have the effect of promoting the secretion of γ-interferon, or the effect is relatively small, and their application in tumor immunotherapy has certain limitations.
Method used
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Embodiment 1
[0042] The embodiment of the present invention provides a tumor immune medicine, the active ingredient of which is suzilactone.
Embodiment 2
[0044]The embodiment of the present invention provides a tumor immune composition, the active components of which are suzilide and kaempferol in a molar ratio of 1:1.
Embodiment 3
[0046] The embodiment of the present invention provides a tumor immune composition, the active components of which are suzilide and kaempferol in a molar ratio of 2:3.
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The invention belongs to the technical field of natural product anti-tumor, and particularly relates to application of surazil lactone in preparation of a tumor immune drug, the tumor immune drug and a composition. Researches find that the surazil lactone can effectively promote immune cells to secrete gamma-interferon, has the effects of improving the vitality of the immune cells and reducing the vitality of tumor cells, and can be used for preparing tumor immune drugs. In addition, the suzillactone, the kaempferol and the quercetin also have a synergistic effect, and can be used for preparing tumor immune drugs in a combined manner.
Description
technical field [0001] The invention belongs to the technical field of natural product anti-tumor, and particularly relates to the application of suzilactone in the preparation of tumor immune drugs, as well as tumor immune drugs and compositions. Background technique [0002] Cancer originates from malignant lesions of epithelial tissue, which is a complex multi-factor and multi-step process. The causes of cancer are closely related to smoking, infection, occupational exposure, environmental pollution, unreasonable diet, and genetic factors. During the course of the disease, the spread of cancer cells can damage cells outside the diseased site and eventually lead to the death of the patient. [0003] Cancer treatments include surgery, chemotherapy, radiation therapy, and immunotherapy. Surgical treatment is suitable for early or earlier solid tumors, but cannot eradicate all cancer cells if they have spread and metastasized; chemotherapy drugs are mostly non-specific, caus...
Claims
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IPC IPC(8): A61K31/365A61P35/00A61P15/14A61P37/04A61K31/352
CPCA61K31/365A61K31/352A61P35/00A61P15/14A61P37/04A61K2300/00
Inventor 李青山刘海鑫侯莉莉
Owner SHANXI UNIV OF CHINESE MEDICINE