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Medicine for treating diabetic nephropathy and its preparing method

A technology for diabetic nephropathy and drugs, applied in the field of drugs for the treatment of diabetic nephropathy, can solve problems such as poor pertinence and unsatisfactory curative effect, and achieve the effects of improving mental state, protecting renal function, and reducing the specific viscosity of whole blood

Inactive Publication Date: 2004-12-29
张晴龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine advocates comprehensive measures such as controlling blood sugar, lowering blood pressure, eating a low-protein diet, and using aldose reductase inhibitors, but they can only improve the early stage of DN. No significant effect
The Chinese patent medicines used for DN mainly include Shenfukang Capsules, Shenyanfufu Tablets, etc. However, due to the lack of specificity, the curative effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Weigh 650g of astragalus, 200g of cornus officinalis, 420g of rehmannia glutinosa, 400g of wine rhubarb, 450g of kudzu root, 320g of Alisma, 550g of salvia miltiorrhiza, combine the above seven flavors together, add 10 times the amount of 90% ethanol, heat and reflux extraction twice, 3 hours each time, Combine the alcohol extracts, recover the ethanol under reduced pressure until there is no alcohol smell, let it stand overnight, filter, concentrate the filtrate under reduced pressure to a relative density of 1.20 (60°C), and dry it in vacuum to obtain the alcohol extract concentrate. Separately weigh 500g of motherwort, 300g of peach kernel, 400g of heterophylla, 440g of medlar and the medicinal residue after alcohol extraction, add 8 times the amount of water, heat and decoct 3 times, each time for 1 hour, filter the medicinal liquid, and combine the medicinal liquid , high-speed centrifugation (12000r / min), the centrifugate is ultrafiltered with an ultrafiltration me...

Embodiment 2

[0020] Weigh 500g of astragalus, 350g of cornus officinalis, 400g of rehmannia glutinosa, 450g of wine rhubarb, 500g of kudzu root, 360g of Alisma, 600g of salvia miltiorrhiza and the above Qiwei, add 8 times the amount of 80% ethanol, heat and reflux extraction 3 times, each time for 1.5 hours, combine For the alcohol extract, recover the ethanol under reduced pressure until there is no alcohol smell, leave it overnight, filter, concentrate the filtrate under reduced pressure to a relative density of 1.25 (60°C), and dry it in vacuum to obtain the alcohol extract concentrate, and the residue after alcohol extraction is ready for use. Separately weigh 400g of motherwort, 300g of peach kernels, 600g of heterophylla, 400g of medlar and alcohol-extracted medicinal residues, add 12 times the amount of water, heat and decoct twice, each time for 2 hours, filter the medicinal solution, and combine twice The liquid medicine is centrifuged at a high speed (15000r / min), and the centrifu...

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Abstract

A Chinese medicine for treating diabetes and nephrosis is prepared from 11 Chinese-medicinal materials including astragalus root, red sage root, peach kernel, wolfberry fruit, etc. Its preparing process is also disclosed. Its advantages are high curative effect and no untoward effect.

Description

Technical field [0001] The invention relates to a medicine for treating diabetic nephropathy, in particular to a Chinese patent medicine prepared from Chinese herbal medicine, and also relates to a preparation method of the medicine. Background technique [0002] Diabetic nephropathy (Diabetic Nephropathy, DN) is a common and refractory complication of diabetes, and it is one of the main causes of death in diabetic patients. According to reports, diabetic nephropathy accounts for 40% of all newly diagnosed end-stage renal diseases, and uremia deaths due to diabetic nephropathy account for about 32% of diabetic patients. Since there is currently no effective method to prevent the occurrence and development of diabetic nephropathy, once the disease occurs, its condition is often irreversible and develops progressively until renal failure. Currently, there is no effective treatment for DN. Western medicine advocates comprehensive measures such as controlling blood sugar, lowe...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61P3/10A61P13/12
Inventor 张晴龙
Owner 张晴龙
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