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Prepn. method of freezing-drying powder injection for anticancer made of Chinese herb medicines

A technology of freeze-dried powder injection and traditional Chinese medicine, which is applied in the field of preparation of anti-cancer traditional Chinese medicine freeze-dried powder injection, which can solve the problems of refractory treatment, damage to normal tissue cells, and failure to fundamentally prevent the regeneration and reproduction of cancer cells.

Inactive Publication Date: 2006-01-25
张正生
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although surgery can remove the primary focus, it cannot fundamentally prevent the regeneration and reproduction of cancer cells, which is the root cause of cancer recurrence and metastasis in the future. Although radiotherapy and chemotherapy can kill cancer cells, it also makes a large number of cancer cells. The normal tissue cells in the body are damaged, which induces gastrointestinal reactions, bone marrow suppression, and liver, kidney, and heart function damage, making the patient's body weaker and difficult to accept further treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Mice S 180 tumor growth inhibitory effect

[0030] Experimental animals: healthy mice, weighing 16-20g, male and female. (Provided by Beijing University of Traditional Chinese Medicine)

[0031] Tumor strain: mouse S 180 (Provided by Beijing University of Traditional Chinese Medicine)

[0032] Experimental drug: normal saline (provided by the laboratory of Beijing Qianluchun Technology Co., Ltd.)

[0033] Commercially available Kangai injection (purchased by Beijing Baitasi Pharmaceutical Wholesale Company, produced by Changbaishan Pharmaceutical Co., Ltd.)

[0034] Freeze-dried powder injection of the present invention (provided by the laboratory of Beijing Qianluchun Science and Technology Co., Ltd.)

[0035] Experimental method: Take the inoculated passage mouse S 180 , add saline to the homogenizer to make mouse S 180 Tumor homogenate was diluted with normal saline 1:3, and then 0.2ml was injected into the subcutaneous area of ​​the left armpit of mice, weigh...

Embodiment 2

[0039] Comparison of Inhibition of Liver Tumors in Rats

[0040] Experimental animals: 30 rats, 150g-180g, male or female, were divided into 3 groups, 10 rats in each group, used for the blank group and the experimental groups of the two preparations respectively.

[0041] Experimental drug: normal saline (provided by the laboratory of Beijing Ganluchun Technology Co., Ltd.) commercially available Kangai injection (purchased by Beijing Baitasi Pharmaceutical Wholesale Company, produced by Changbaishan Pharmaceutical Co., Ltd.)

[0042] Freeze-dried powder injection of the present invention (provided by the laboratory of Beijing Qianluchun Science and Technology Co., Ltd.)

[0043] Experimental method: Take rats for intrahepatic inoculation of W256. Seven days after the inoculation, they were anesthetized by intraperitoneal injection of pentobarbital sodium at a dose of 35 mg / kg, fixed, exposed the liver by laparotomy, and measured the maximum diameter of the tumor surface on t...

Embodiment 3

[0050] Physical, chemical and biological factors can all induce cancer, but 80%-90% of the causes of human cancer are believed to be caused by environmental chemicals.

[0051] Inhibitory effects of two preparations on diethylnitrosamine (DENA)-induced liver cancer in rats

[0052] Experimental animals: 30 rats, about 120 g, male or female, were divided into 3 groups, 10 rats in each group, used for the blank group and the experimental groups of the two preparations respectively.

[0053] Experimental drug: normal saline (provided by the laboratory of Beijing Ganluchun Technology Co., Ltd.) commercially available Kangai injection (purchased by Beijing Baitasi Pharmaceutical Wholesale Company, produced by Changbaishan Pharmaceutical Co., Ltd.)

[0054] Freeze-dried powder injection of the present invention (provided by the laboratory of Beijing Qianluchun Science and Technology Co., Ltd.)

[0055] Experimental method: Rats were fed with drinking water containing diethylnitrosa...

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Abstract

An anticancer Chinese medicine in the form of freeze-dried powder injection is prepared from ginseng, astragalus root and flavescent sophora root through extracting, respectively, proportional mixing and freezy drying.

Description

Technical field [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and in particular relates to a preparation method of anticancer traditional Chinese medicine freeze-dried powder injection. Background technique [0002] Cancer is a kind of disease that seriously threatens human life and health. According to the latest statistical data, about 1 million cancer patients are newly discovered in my country every year, and cancer kills about 6 million people every year in the world, and puts 10 million people on the brink of death. With the deteriorating environment of human beings, The incidence of cancer is increasing year by year. The World Health Organization predicts that cancer will become the "first killer" of human beings in the 21st century. The current modern medical treatment of cancer is mainly surgical treatment combined with radiotherapy and chemotherapy. Although surgery can remove the primary focus, it cannot fundamentally preven...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/48A61K36/481A61K36/258A61K9/19A61P35/00
Inventor 张正生
Owner 张正生