Fast dispersing dosage forms free of gelatin
A fast and decentralized technology, applied in pill delivery, medical preparations of non-active ingredients, drug delivery, etc., can solve the problems of non-disclosure
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Embodiment 2
[0115] Perfectagel MPT is hydroxypropyl distarch phosphate, which is commercially available from AVebe U.K., Ltd.
[0116] components
amount (g)
weight%
Paselli MD 10
10
10
3
3
87
87
[0117] Paselli MD 10 is an enzyme modified starch which is commercially available from Avebe U.K., Ltd.
[0118] Stir the water with an electric mixer with a handle and stir in the starch and mannitol. The starch does not require heating. The solution was stirred for 1.5 hours to equilibrate.
[0119] The dosage form disperses smoothly and quickly in the mouth and has a sweet taste.
Embodiment 4
[0122] Avebe MD20 is an enzyme modified starch which is commercially available from Avebe U.K., Ltd.
[0123]The dosage forms prepared in Examples 1-4 all disintegrated rapidly in the mouth in less than 10 seconds.
Embodiment 5
[0125] Study on Viscosity Curves of Various Modified Starches
[0126] components
[0127] Ingredients
[0128] No significant change in viscosity was observed over the 22 hour period. This is a highly desired property in the preparation of FDDF's. This property improves the potency of the product and reduces losses due to waste.
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