Mixed live bacillus drops of bifidobacterium and lactobacillaceau and its prepn

Abstract

The mixed live bacillus drops are prepared by separating and identifying one strain of bifidobacterium and one strain of lactobacillaceau from vagina vault of some young and healthy women and throughin vitro mutagenesis and culture, oxytolerant acclimation, adding dispersant and freeze drying. During the preparation, the strains are increased in PYG anaerobic bacillus culture medium to 10 to thepower 9 to 10 the power 11 / ml over density; the bacillus liquid is mixed with skimmed milk, cane sugar dispersant, glutin and glycerine excipient; the mixture is frozen in -80 deg.c for 30-60 min, freeze dried at -30 to 70 deg.c within 22-26 hr; and the two kinds of live bacillus powder are mixed and made into pills. The strains of the present invention is stable, no drug resistance and oxytolerant, and has the infection resisting effect, wide bacteriostasis spectrum and antineoplastic immunoregulating effect; and is suitable for industrial production.

Description

technical field [0001] The invention relates to a western medicine preparation, in particular to a bifidobacterium and lactobacillus mixed living bacteria drop for preventing and treating various specific and non-specific gynecological inflammations and gynecological tumors and a preparation method. Background technique [0002] The current theory of western medicine points out that the imbalance of vaginal micro-ecological environment is the main cause of various gynecological inflammations, and the occurrence of some gynecological tumors is also related to it. How to restore and maintain vaginal micro-ecological balance is a hot spot of current research. In the past, vaginal microecological preparations were single strains, and their effects were mostly limited to the treatment of bacterial vaginosis, and most of them were suppositories. During the production process, glycerin and other compressive agents had to be added at a higher temperature, which would increase the amo...

AI Technical Summary

Problems solved by technology

In the past, vaginal microecological preparations were single strains, and their effects were mostly limited to the treatment of bacterial vaginosis, and most of them were suppositories. During the production process, glycerin and other compressive agents needed to be added at a higher temperature, which would increase the amount of dead bacteria and affect the efficacy of the drug. effect