Piezoelectrically driven microspray method and apparatus for atomizing administration

Abstract

A method and apparatus for atomizing medicine before it is applied to human body is disclosed. Said apparatus is composed of elastic cavity with micro spray holes, piezoelectric ceramic and liquid feeding tube. Under the action of electric signals, the vibration of said elastic cavity is generated to generate pressure waves, which can extrude liquid medicine out from said spray holes, so atomizing it. Its advantages are no destroy to environment, high size uniform of atomized particles, and high utilization rate of medicine.

Description

technical field [0001] The invention belongs to a method and a device for injecting medicine into a human body after atomization, in particular to a piezoelectric-driven micro-spraying method and a device for atomizing medicine. Background technique [0002] figure 1 It is an existing medical quantitative and constant pressure aerosol device (Genova; Perry A. Metered dose inhaler agitator. United States Patent, 6116234, 2000-09-12), comprising a pressure-resistant container 1, content 2, sleeve 3, Quantitative control valve 4, spray rod 5, atomizing nozzle 6, elastic material 7. The pressure-resistant container 1 is pre-filled with content 2, and the content 2 includes liquid medicine, additives and liquid propellants with high pressure (higher than atmospheric pressure). The pressure vessel 1 can move up and down in the sleeve 3 . When applying, use your hands downward (such as figure 1 (shown by the middle arrow) press the pressure-resistant container 1, the spray rod ...

AI Technical Summary

Problems solved by technology

For the existing quantitative and constant pressure aerosol device, due to the influence of factors such as ambient temperature and propellant concentration, the propellant cannot be completely vaporized, and the atomization of the liquid medicine is not complete; in addition, the adiabatic expansion of the propellant will cool the mist. Therefore, the diameter of the atomized particles of the current quantitative and constant pressure aerosol device is relatively large, generally 20-50 μm, such large fog particles are difficult to reach the lungs, which is not conducive to the lungs Inhalation administration (Sperry; Charles R. Inhalation device. United States Patent, 4852561, 1989-08-01)

Quantitative constant pressure aerosol device generally has a relatively high speed of mist particles, and the speed of mist particles is easier to hit the mouth, it is difficult to reach the lungs, and it is not conducive to lung inhalation and drug administration.

In addition, the diameter distribution of atomized particles of the current quantitative and constant pressure aerosol device is not concentrated enough, so that the drug dose utilization rate of atomized drug administration is low, which not only causes a lot of waste of drugs, but also because the particle size distribution is relatively dispersed, the drug particles cannot be used. Reaching the correct drug absorption site, but also brings some side effects

[0004] The propellant in the early quantitative constant pressure aerosol device is Freon, which has good physical and chemical properties and has been used as an ideal propellant, but Freon is the main cause of the destruction of the atmospheric ozone layer

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