Piezoelectrically driven microspray method and apparatus for atomizing administration

A piezoelectric drive and drug delivery technology, applied in the direction of nebulizer for treatment, can solve the problems of drug waste, atmospheric ozone layer destruction, unfavorable drug delivery, etc., and achieve the effect of reducing side effects and improving utilization rate

Inactive Publication Date: 2002-07-24
TSINGHUA UNIV
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Problems solved by technology

For the existing quantitative and constant pressure aerosol device, due to the influence of factors such as ambient temperature and propellant concentration, the propellant cannot be completely vaporized, and the atomization of the liquid medicine is not complete; in addition, the adiabatic expansion of the propellant will cool the mist. Therefore, the diameter of the atomized particles of the current quantitative and constant pressure aerosol device is relatively large, generally 20-50 μm, such large fog particles are difficult to reach the lungs, which is not conducive to the lungs Inhalation administration (Sperry; Charles R. Inhalation device. United States Patent, 4852561, 1989-08-01)
Quantitative constant pressure aerosol device generally has a relatively high speed of mist particles, and the speed of mist particles is easier

Method used

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  • Piezoelectrically driven microspray method and apparatus for atomizing administration
  • Piezoelectrically driven microspray method and apparatus for atomizing administration
  • Piezoelectrically driven microspray method and apparatus for atomizing administration

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[0014] According to application requirements and related research results, the present invention is based on the basic principle of piezoelectric driven inkjet printers, and uses MEMS (Micro Mechanical Electronic System) technology to develop such figure 2 , 3 , 4 shows the piezoelectric drive type atomized drug delivery array micro spray device. figure 2 In the device shown, the elastic cavity mold is composed of left and right elastic cavity molds, where 8 represents the left elastic cavity mold silicon chip, 9 represents the circular piezoelectric ceramic chip, 10 represents the right elastic cavity mold silicon chip, and 11 Represents the round micro nozzle hole processed in the right elastic cavity mold silicon chip 10, 12 is the elastic mold cavity formed by the left elastic cavity mold silicon chip 8 and the right elastic cavity mold silicon chip 10, 13 is the liquid supply tube, and 14 is the electrode lead . Depending on whether the micro-aerosol delivery site is the or...

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Abstract

A method and apparatus for atomizing medicine before it is applied to human body is disclosed. Said apparatus is composed of elastic cavity with micro spray holes, piezoelectric ceramic and liquid feeding tube. Under the action of electric signals, the vibration of said elastic cavity is generated to generate pressure waves, which can extrude liquid medicine out from said spray holes, so atomizing it. Its advantages are no destroy to environment, high size uniform of atomized particles, and high utilization rate of medicine.

Description

technical field [0001] The invention belongs to a method and a device for injecting medicine into a human body after atomization, in particular to a piezoelectric-driven micro-spraying method and a device for atomizing medicine. Background technique [0002] figure 1 It is an existing medical quantitative and constant pressure aerosol device (Genova; Perry A. Metered dose inhaler agitator. United States Patent, 6116234, 2000-09-12), comprising a pressure-resistant container 1, content 2, sleeve 3, Quantitative control valve 4, spray rod 5, atomizing nozzle 6, elastic material 7. The pressure-resistant container 1 is pre-filled with content 2, and the content 2 includes liquid medicine, additives and liquid propellants with high pressure (higher than atmospheric pressure). The pressure vessel 1 can move up and down in the sleeve 3 . When applying, use your hands downward (such as figure 1 (shown by the middle arrow) press the pressure-resistant container 1, the spray rod ...

Claims

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Application Information

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IPC IPC(8): A61M11/00
Inventor 周兆英刘长庚王晓浩叶雄英王国辉袁松梅
Owner TSINGHUA UNIV
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