Myocarditis treating medicine

A technology of myocarditis and medicine, which is applied in the field of traditional Chinese medicine Radix Radix Radix Astragali as a medicine for treating myocarditis, which can solve the problems of large side effects, poor effect and unsatisfactory effects of antiviral drugs, and achieve obvious protective effect

Inactive Publication Date: 2003-01-08
首都儿科研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effect of energy mixture is not good, and the side effects of antiviral drugs are relatively unsatisfactory, and some of them have been discontinued. The number of approved traditional Chinese medicines in China is very small, and the curative effect is not satisfactory, and the drugs for children are still blank.

Method used

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Examples

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Embodiment

[0015] This example is a specific method for preparing total saponins. Specific process:

[0016] The rhizome of Radix Radix Radix Radix Radix Radix Radix Radix Radix Radixe is crushed, weighed 800 grams, cold soaked with methanol three times, 2000 milliliters each time, filtered, and combined methanol filtrate. Recover methanol by distillation under reduced pressure to obtain the extract. The extract was diluted with 500 ml of water and degreased three times with ether, 200 ml each time. The aqueous portion was extracted three times with 500 ml of saturated n-butanol. The n-butanol extract was evaporated to dryness under reduced pressure to obtain 8.2 g of total saponins (light yellow powder), with an extraction rate of about 1%. Then the total saponins are formulated into oral liquid or injection.

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Abstract

The medicine for curing myocarditis is characterized by that it is an oral liquor or intravenous injection made up by using total saponin extracted from Chinese medicinal materials sweetvetch root and sterile physiological saline or phosphoric acid buffer solution through a certain preparation process. It possesses the obvious effect for resisting myocarditis virus and inhibiting pathopoiesis of Coxsackie B3 virus cell, as compared with virazole it possesses obvious protection action for myocarditis, and has no any toxic side effects.

Description

technical field [0001] The invention relates to a medicine for treating myocarditis, more specifically, the extract of the traditional Chinese medicine Radix Astragali as a medicine for treating myocarditis. Background technique [0002] Viral myocarditis is one of the diseases that cause high mortality in newborns and children. Most patients develop a chronic myocarditis process that eventually leads to cardiomyopathy. Even in developed countries with advanced medical care, the five-year survival rate of patients with cardiomyopathy is very low. The main reason for this process is that the early onset of myocarditis is easy to be ignored, and after the occurrence of cardiomyopathy in the protracted period of chronic myocarditis, there is a lack of survival. Effective drug treatment has caused no substantial progress in the treatment of myocarditis for many years, and has become one of the diseases that seriously endanger the physical and mental health of children and adole...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7042A61P9/00A61P29/00A61P31/00A61P31/12
Inventor 崔小岱蒋岩马连华张宝元鲁杰张霆
Owner 首都儿科研究所
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