Medicine releasing control method for implanting type medical equipment

Abstract

The present invention provides a method of preparing inorganic and organic composite coating to control medicine release on the surface of implanted medical equipment. The inorganic material is silicon sol or titanium sol and the organic material is polymer with excellent biocompatibility and filming performance. The present invention combines the excellent performance of inorganic material and polymer and is superior to available inorganic and organic coating and is suitable for long-period controlled release of medicine sensitive to outer heat, light and other conditions.

Description

field of invention

[0001] The invention belongs to the technical field of medical devices, in particular to a method for controlling drug release applied to implantable medical devices, in particular to a method for controlling drug release by using an organic / inorganic composite coating. Background technique

[0002] In the current surgical operation or interventional treatment methods, it is often necessary to implant some special medical devices in the patient's body for treatment, such as heart valves, valve rings, stents in blood vessels and digestive tracts, and the like. These implantable medical devices made of metal or polymer materials are being used to treat more and more diseases. However, these implants may also cause the following side effects in the human body, including: increasing the possibility of postoperative infection; triggering foreign body reactions, causing inflammation or local fibrosis; triggering wound healing reactions to cause local tissue hype...