Composition for hair and/or scalp
A composition and hair technology, applied in hair care, drug combination, skin diseases, etc., can solve problems such as lack, unclear effect, and unknown activity of hair repair oil medicine
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Embodiment 1
[0031] The hair on the back of male C3H mice (7 weeks old) in the telogen phase was carefully removed, and then the mice with no back injuries were divided into groups of 7 mice for the experiment. In the control group, each mouse was only given polyethylene glycol 1000 (PEG1000) as a matrix; in the evaluation group, 10% oxidized coenzyme Q was applied to the shaved part 10 or 10% reduced coenzyme Q 10 (reduced coenzyme Q 10 : Oxidized coenzyme Q 10=95:5), once a day, 14 times in total. After dosing, the back of each mouse was evaluated according to the following scores to evaluate the hair restoration activity of the compound.
[0032] Fraction:
[0033] 1: the skin turns pink;
[0034] 2: Less than 30% of the shaved area turns gray;
[0035] 3: Less than 60% of the shaved areas become gray, or hair growth is observed in less than 30% of the shaved areas;
[0036] 4: 60% or more of the shaved areas turned gray, or hair growth was observed in less than 60% of the shaved...
Embodiment 2
[0044] The activity of preventing hair loss was evaluated in 4-week-old male hairless rats in the anagen phase. Using the same sample as in Example 1, 5 hairless rats in every group, each sample was applied to the back of each rat, once a day, for 12 days in total, and the hair loss state was observed after stopping the application. The hair removal status was evaluated according to the following scores.
[0045] Fraction:
[0046] 1: No depilation was observed;
[0047] 2: Hair shortening in 30% or less of the treated area;
[0048] 3: Shortening of hair in 60% or less of the applied area, and hair loss observed in 30% or less of the applied area;
[0049] 4: Shortening of hair in 60% or more of the applied areas, and hair loss observed in 30% or more of the applied areas;
[0050] 5: Hair loss is observed in 60% or more of the applied area
[0051] The results on the 71st day after the end of the application are shown in Table 2.
[0052] Table 2
[0053] B...
preparation Embodiment 1
[0057] Coenzyme Q containing 10 hair tonic (hairtonic).
[0058] Olive oil 5.0% by weight
[0059] Isopropyl myristate 2.0% by weight
[0060] Isopropylmethylphenol 0.1% by weight
[0061] Ethanol 55.0% by weight
[0062] Glycerin 5.0% by weight
[0063] Methylparaben 0.1% by weight
[0064] coenzyme Q 10 (Reduced form: 95% 1.0% by weight
[0065] weight; oxidized form: 5% by weight)
[0066] Purified water 100.0% by weight
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