Suppository for treating gynecological inflammation and its preparation method

A Fuyanping suppository and preparation technology, which is applied in suppository delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve problems such as inconvenient use of powders, irritation of inflammatory mucosa, increased contact between drugs and medication sites, etc. Achieve the effect of guaranteeing medication needs, non-irritating, and high compliance

Inactive Publication Date: 2005-01-05
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The original powders, capsules, and effervescent tablets have good curative effects in treating women’s vaginitis, cervicitis, and vulvitis caused by damp-heat accumulation, but the powders have the disadvantage of being inconvenient to use; the hard capsule shell dissolves slowly; efferve...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The nine medicines are tested separately for use; crush Sophora flavescens, bitter wood and Fructus Cnidii into coarse powder, use 80% ethanol as a solvent, soak for 48 hours, slowly percolate, collect percolate, recycle ethanol, concentrate to Appropriate amount, spray-dried, and collected dry cream powder for later use; dried alum, boric acid, berberine hydrochloride, nacre powder, borneol, and menthol were respectively pulverized into fine powders, and mixed with the above dry cream powder for later use; another semi-synthetic fatty acid lipid Appropriate amount, heat and melt, the temperature drops to about 50°C, add the above-mentioned medicinal powder, stir well, pour into the suppository mold, take it out after solidification, and pack it.

Embodiment 2

[0035] The nine medicines are tested respectively for later use; Cnidium is crushed into coarse powder, percolated with 85% ethanol, Sophora flavescens is percolated with 50% ethanol, the liquid is collected, combined, and the ethanol is recovered for later use; Bitterwood is heated with 80% ethanol Extract twice, each time for 2 hours, filter the extract, recover ethanol, combine with the above extracts such as Fructus Cnidii, concentrate to an appropriate amount, dry under reduced pressure, and pulverize into dry cream powder for later use; dry alum, boric acid, berberine hydrochloride , nacre powder, borneol, and menthol were crushed into fine powders, and mixed with the above-mentioned dry paste powder for later use; another appropriate amount of semi-synthetic fatty acid fat was taken, heated and melted, and the temperature dropped to about 50°C, added the above-mentioned medicinal powder, and fully stirred, Pour into the suppository mold, take it out after solidification,...

Embodiment 3

[0037] Nine medicinals are tested to be qualified respectively for later use; Fructus Cnidii is crushed into a coarse powder, and 80% ethanol is used as a solvent, and after soaking for 48 hours, slowly percolated, the percolation liquid is collected, ethanol is recovered, concentrated to an appropriate amount for later use; the dregs of the medicine are mixed with Decoct bitter wood and kulan with water twice, 2 hours each time, combine the decoction, filter, concentrate to an appropriate amount, mix with the above-mentioned cnidium alcohol extract, dry under reduced pressure, and crush into dry cream powder for later use; dry alum , boric acid, berberine hydrochloride, nacre powder, borneol, and menthol were crushed into fine powders, and mixed with the above-mentioned dry cream powder for later use; another appropriate amount of semi-synthetic fatty acid fat was taken, heated and melted, and the temperature dropped to about 50°C, and added The above-mentioned medicinal powde...

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PUM

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Abstract

An improved Chinese medicine 'Fuyanping suppository' for treating vaginitis and vulvitis with higher curative effect and safety and no stimulation is disclosed.

Description

technical field [0001] The invention relates to the technical field of manufacturing Chinese patent medicine suppositories, in particular to Fuyanping suppositories and a preparation method thereof. Background technique [0002] Suppository is a commonly used traditional Chinese medicine form. According to the relevant drug laws and regulations of our country, changing the dosage form is regarded as a new drug research. The original dosage form Fuyanping powder and Fuyanping capsule (external use) have been included in the drug standard of the Ministry of Health of the People's Republic of China "Prescriptions of Traditional Chinese Medicine" In volumes 17 and 18, Fuyanping effervescent tablets are new drugs. Women's vaginitis, cervicitis, and vulvitis are common and frequently-occurring diseases of women. The original powders, capsules, and effervescent tablets have good curative effects in treating women’s vaginitis, cervicitis, and vulvitis caused...

Claims

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Application Information

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IPC IPC(8): A61K9/02A61P15/02
Inventor 毛友昌毛晓敏
Owner 毛友昌
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