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'Mikang' gels of Chinese traditional medicine for curing inflammation of cervical erosion etc. and preparation method

A technology of cervical erosion and gel, which is applied in the field of medicine and can solve the problems of short action time and slow drug effect

Inactive Publication Date: 2005-01-12
SHENYANG PHARMA UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, most of the drugs for treating cervicitis such as cervical erosion are suppositories, but this dosage form exerts the drug effect relatively slowly and the drug will become liquid and flow out of the vagina after melting, and the action time is short.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0011] The preparation method of traditional Chinese medicine Mikang gel is as follows:

[0012] (1) Disperse carbomer in water at a ratio of 1 g: 10-100 ml and place it overnight for later use.

[0013] (2) Dissolve 2 to 10 grams of Sophora flavescens extract in water, then add 0.01 to 1 gram of EDTA-2Na, and set aside.

[0014] (3) Take 1-10 grams of Fructus Cnidii extract, add 0.01-10 grams of Tween-80, grind well, then add absolute ethanol, disperse and grind well, finally add propylene glycol, grind well, set aside.

[0015] (4) Add the prepared Fructus Cnidii Extract (3) into 10-100 grams of dispersed carbomer (1) and grind evenly, then add the prepared Sophora flavescens extract (2) into it and continue grinding Evenly, add appropriate amount of water, that is.

[0016] The preparation method of Fructus Cnidii extract: put Fructus Cnidii medicinal material in the extraction container, soak for 10 minutes with 1% (w / v) sodium hydroxide aqueous solution of 10 times the ...

Embodiment

[0019] 1 traditional Chinese medicine Mikang gel

[0020] Prescription: Fructus Cnidii Extract 150g

[0021] Sophora flavescens extract 300g

[0022] Carbomer 125g

[0023] Make 1000 gels

[0024] Preparation method: Prepare the prescription amount of extract and auxiliary materials according to the preparation method of gel, and obtain it.

[0025] 2 Traditional Chinese Medicine Mikang Capsules

[0026] Prescription: Fructus Cnidii Extract 200g

[0027] Sophora flavescens extract 300g

[0028] Mannitol 300g

[0029] Pack 1000 capsules

[0030] Preparation method: mix the prescribed amount of extract and supporting agent mannitol, and put them into capsules.

[0031] 3 Traditional Chinese Medicine Mikang Tablets

[0032] Prescription: Fructus Cnidii Extract 200g

[0033] Sophora flavescens extract 100g

[0034] Mannitol 300g

[0035] Made into 1000 pieces

[0036] Pr...

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PUM

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Abstract

A Chinese medicine in the form of gel, ointment, or suppository for treating cervical erosion, cervicities, and vaginitis is prepared from flavescent sophora root, cnidium fruit and pharmacologically acceptable matrix through extracting, dissolving, mixing with carbomer solution or said matrix, dispersing, and regulating pH=2-12.

Description

Technical field: [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine Mikang gel for treating cervicitis such as cervical erosion, a composition thereof and a preparation method thereof. Background technique: [0002] Cervicitis is currently the most common gynecological disease, in which cervical erosion is the main manifestation. The cervical erosion lesion is located in the columnar epithelium of the endocervical endometrium, and it is difficult for general pharmaceutical preparations to act on it. According to the epidemiological survey results of 15 provinces, autonomous regions, and municipalities organized by the Ministry of Health in 2000, cervicitis, mainly manifested by cervical erosion, ranks first in gynecological diseases in my country, and the incidence rate is 28.9% of married women. . There are few drugs for treating cervicitis such as cervical erosion. Until 2000, the drugs approved by the state fo...

Claims

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Application Information

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IPC IPC(8): A61K9/00A61P15/00A61P15/02
Inventor 张国刚田宏徐绥绪
Owner SHENYANG PHARMA UNIVERSITY
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