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Method for preparing artificial head bones made from composite material and for modifying surface

A composite material, skull technology, applied in medical science, prosthesis, etc., to achieve the effect of high biological activity and good osseointegration

Inactive Publication Date: 2005-01-12
WUHAN UNIV OF TECH
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Problems solved by technology

[0005] At present, there is no literature report that the composite material of polymethyl methacrylate and bio-inorganic fiber and hydroxyapatite micropowder or β-tricalcium phosphate micropowder is used for skull repair, and the surface of the material is modified to improve the surface hardness of the material. bioactivity and osseointegration

Method used

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  • Method for preparing artificial head bones made from composite material and for modifying surface
  • Method for preparing artificial head bones made from composite material and for modifying surface
  • Method for preparing artificial head bones made from composite material and for modifying surface

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Embodiment 1

[0028] 1. Preparation of composite artificial skull

[0029] The preparation method is to carry out bulk polymerization of methyl methacrylate (MMA) and polymethyl methacrylate (PMMA) at a ratio of 5:3 (mass ratio), without adding other initiators. The composite board is made of multi-layer composite technology, and a layer of biological glass fiber (or carbon fiber) is laid on each layer inside, and a layer of methyl methacrylate and polymethyl methacrylate bulk polymer is applied to make biological carbon fiber or glass fiber And MMA and PMMA homogeneous body; the upper and lower surfaces are coated with hydroxyapatite (HA) and MMA and PMMA composite, the method is to coat hydroxyapatite on the surface of methyl methacrylate and polymethyl methacrylate bulk polymer Stone (or β-tricalcium phosphate); put the composite board into an oven, control the temperature at 55-65°C, and keep it warm for 3 hours to make it preliminarily polymerized. Then use hot molding technology to p...

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Abstract

An artificial skull with high surficial bioactivity is prepared from methyl polymethacrylate, biological carbon (or glass) fibres and hydroxy apatite (or beta-tricalcium phosphate) micropowder through laminating or hot pressing, and immersing in simulative body fluid.

Description

technical field [0001] The invention relates to the preparation and surface modification method of a composite material artificial skull for repairing human skull defects. Background technique [0002] Due to traffic and industrial accidents and brain diseases, the number of patients who need cranioplasty is increasing year by year. In my country, there are more than 500,000 patients with skull injuries every year. It is urgent to study an ideal skull replacement material. [0003] The materials that have been used in the repair of skull defects are mainly metal materials and polymer materials. Among them, the metal material, because the patient's head is sensitive to the external temperature difference, makes the patient feel uncomfortable, and the long-term temperature difference change will damage the brain tissue. Polymethyl methacrylate and other polymer materials that have been widely used have the characteristics of good biocompatibility and convenient molding and pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/44
Inventor 阎玉华陈晓明李世普万涛朱晏军贺建华江昕李建华
Owner WUHAN UNIV OF TECH
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