The invention provides a bone plate for human skull defect repair and a preparing method and a using method of the bone plate. Compared with a titanium alloy net plate as the first choice for skull repair currently and clinically, the heat conductivity coefficient of the polyether-ether-ketone high polymer material bone plate is low, and the phenomenon of the encephalic discomfort generated by thesensitivity to temperature change after a patient adopts the titanium alloy net plate for repair is avoided. According to a skull defect part CT scanning picture of the patient, after the shape and the size of the defect part are determined, by individually designing processing and preparing, embedded installation and fixation are adopted by an operation, the preoperative cutting and shaping process of the repair of the titanium alloy net plate is replaced, it is avoided that the scalp is injured accidentally since the cutting edge of the titanium net plate is sharp, postoperatively, the outward leakage of cerebrospinal fluid and even a complication of infection caused when the sharp titanium net plate scratches the scalp are thoroughly removed, an artifact existing under an image by theadoption of the titanium alloy net plate for repair is also removed, and the influence of the artifact on later diagnosis and judgment of the state of illness clinically is effectively avoided.