15 results about "Hearing Impaired Persons" patented technology

Provided herein are compositions that include at least two different nucleic acid vectors, where each of the at least two different vectors includes a coding sequence that encodes a different portion of an otoferlin protein, and the use of these compositions to treat hearing loss in a subject.

This invention provides drugs and methods for preventing or reversing hearing loss. [Solution] A composition comprising at least two different nucleic acid vectors, each of which comprises a coding sequence encoding a different portion of the otoferrin protein, and the use of these compositions for treating hearing loss in a subject are provided herein. This disclosure is based on the discovery that a composition comprising at least two different nucleic acid vectors, each of which comprises a coding sequence encoding a different portion of the otoferrin protein, can be used to generate a sequence encoding an active otoferrin protein (e.g., full-length otoferrin protein) in mammalian cells, thereby enabling the treatment of asymptomatic sensorineural hearing loss in a subject in need.

Provided herein are compositions that include at least two different nucleic acid vectors, where each of the at least two different vectors includes a coding sequence that encodes a different portion of an otoferlin protein, and the use of these compositions to treat hearing loss in a subject.

A hearing aid comprises an input transducer configured to convert sound around a user to at least one electrical input signal representing the sound; an output transducer for providing an audible signal based on the at least one electrical input signal; transceiver circuitry configured to establish a wireless audio communication link with a secondary device; and a processor configured to operate the hearing aid in a system mode or a device mode. The hearing aid is configured to initiate establishment of the wireless audio communication link in dependence of a mode control signal. A non-wearable device comprising transceiver circuitry configured for establishing a wireless audio communication link with a hearing aid comprises a processor configured to receive and process at least one electrical input signal from a hearing aid to at least partially compensate for hearing impairment of a user; a power supply interface. The non-wearable device is integrated with another device having a specific other function.

A system and method for diagnosing hearing impairments in individuals, particularly school-aged children, using voice sample analysis and data from electronic questionnaires. The system utilizes a deep neural network to process extracted acoustic features from voice recordings and correlate them with hearing performance data, generating a predicted audiogram. The system includes a microphone, signal acquisition and processing blocks, a neural network-based analysis engine, and a result interpretation interface.

According to an embodiment, a device for script extraction and subtitle transmission synchronized with live performing art content is provided. When a viewer views verbal performing arts such as plays or musicals, the device projects commentary subtitles synchronized in real time with performance content in a preferred language in front of eyes by using a display device including AR smart subtitle glasses, in order to eliminate a language barrier due to nationality or an auditory barrier caused by hearing impairment or hearing loss and enable viewing of the performing arts, so that the subtitles can be viewed in synchronization with the performance.

The application relates to the field of hearing aids, in particular to a hearing aid sound compensation method, which comprises a system architecture module, the system architecture module is internally provided with an implementation module, an innovation module and a processing module, and the implementation module, the innovation module and the processing module are mutually electrically connected; the implementation module is internally provided with a data acquisition module, a sound compensation model module, a digital signal processing module and a sound output module, hearing data of a user is acquired, a targeted sound compensation model is constructed, and a digital signal processing technology is adopted to realize accurate compensation on a sound signal output by the hearing aid. Experimental results show that the method has obvious advantages in improving the auditory perception quality of the user, provides a more intelligent and personalized hearing solution for the hearing impaired, and can effectively increase the hand-on performance and self-updating performance of the user through individual training and a self-updating module, so that the user can conveniently use the hearing aid.

A pair of bone conduction hearing aid eyeglasses comprises a eyeglass mechanism, wherein at middle portions of both rear sides of the eyeglass mechanism are fixedly connected connection mechanisms, at sides of the connection mechanisms are fixedly connected bone conduction eyeglass leg mechanisms, outside rear-central portions of the bone conduction eyeglass leg mechanisms are sleeved rubber rings, at rear end portions of the bone conduction eyeglass leg mechanisms are fixedly provided connecting buckles, rear end portions of the connecting buckles are fixedly installed at front end portions of an anti-falling mechanism. By arranging bone conduction assemblies within the bone conduction leg mechanisms, patients with hearing impairments and myopia can achieve vision and hearing correction; connecting buckles are connected to automatically retractable anti-falling mechanism, so as to prevent the bone conduction hearing aid eyeglasses from failing off during vigorous movements, thus avoiding potential damage to the bone conduction hearing aid eyeglasses.

This invention relates to the field of air conduction hearing aids, specifically a method for identifying the type of hearing impairment using an air conduction hearing aid. The method includes an identification module, an isolation module, a button module, an adjustment module, and a power control module. The identification module includes an audio cycling module and an audio locking module. The isolation module includes a storage module, a protection module, and a locking module. The button module includes a power button, an adjustment button, and an audio adjustment switch. The air conduction hearing aid is adjusted to fit the user and then worn. Multiple audio frequencies are played in a loop, allowing the user to select the appropriate audio. The selected audio is then switched off to prevent accidental activation and ensure continued usability. Furthermore, the method automatically reselects the audio frequency based on changes in external audio, making it suitable for different environments and users.

Acquired hearing loss due to chemotherapy or noise exposure is a major health problem, and Cisplatin chemotherapy often causes permanent hearing loss in cancer patients. However, there are no FDA-approved drugs for the treatment or prevention of Cisplatin- or noise-induced hearing loss. In one aspect, use of Niclosamide, Ingenol, and Elesclomol as an active agent to treat a hearing impairment and to prevent a hearing impairment, and methods of treating and / or preventing hearing impairments or disorders using the compositions are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

The application relates to the technical field of English learning machines, in particular to an English hearing impairment auxiliary training device. The device comprises a body and a prompting device, the inside of the body is fixedly connected with a touch screen, the inside of the body is fixedly connected with two loudspeakers, the prompting device is arranged on one side of the body, the prompting device comprises a base plate arranged on one side of the body, the inside of the base plate is rotationally connected with a rotating block, the inside of the upper end of the rotating block is inserted with a protective cover, the inside of the protective cover is inserted with two lamp strips, the inside of the two lamp strips is respectively provided with red and green lamp beads, through multi-modal function integration and structured design, in the aspect of information transmission, the device takes the built-in loudspeaker of the body as the basis of hearing, the red and green double-color lamp strips in the protective cover are matched to convert abstract English accent, bass and other speech differences into intuitive visual signals, and the corresponding frequency tactile vibration output by the vibration motor connected with the fixing frame is combined to form a hearing, vision and tactile triple information transmission mechanism.

In the course of this invention, the inventors have demonstrated that intracellular ATP and mitochondrial membrane potential in cells isolated from hearing-impaired patients with BCAP31 gene mutations are significantly lower than in normal individuals. This finding indicates that hearing-impaired patients with BCAP31 gene mutations have significantly impaired mitochondrial function. Furthermore, increased susceptibility to cisplatin-induced cytotoxicity has also been demonstrated. On the other hand, treatment of lymphoid cell lines from these hearing-impaired patients with stem cell-derived isolated mitochondria has been shown to increase intracellular mitochondrial activity and reduce cisplatin-induced cytotoxicity. Moreover, it has been demonstrated that when stem cell-derived isolated mitochondria are applied to lymphocyte cell lines from hearing-impaired patients with ferredoxin reductase (FDXR) gene mutations, and to fibroblasts from hearing-impaired patients with mitochondrial gene mutations (m.A1555G), intracellular mitochondrial function is also restored. Therefore, the mitochondria according to the present invention can effectively alleviate or treat hereditary hearing loss.

The application provides a sound signal processing method based on an acoustic model, which is used for an air conduction hearing aid. The method comprises the following steps: simulating and copying available sound signals in an environment sound signal of the hearing aid, and the number of the available sound signals is at least two; performing differential filtering processing on the available sound signals based on an existing acoustic model to form different pure tone signals; and performing differential processing on the pure tone signals according to categories, and integrating and outputting the processed pure tone signals. Through analysis on the available sound signals in the environment, a related acoustic model combination can be matched, the remaining signals in the available sound signals are processed by masking through the acoustic model, different pure tone signals of different sound types can be obtained, the differential amplification of each pure tone signal is performed according to the degree of hearing impairment of a hearing-impaired patient and then the pure tone signal is output, the ratio of a specific sound to the remaining sounds can be increased, and the resolution of the specific sound is effectively improved.

Acquired hearing loss due to chemotherapy or noise exposure is a major health problem and cisplatin chemotherapy often results in permanent hearing loss in cancer patients. However, there are no FDA-approved drugs for the treatment or prevention of cisplatin- or noise-induced hearing loss. In one aspect, the use of niclosamide, murolic acid, and ilesidomine as active agents to treat and prevent hearing impairment, and methods of using the compositions to treat and / or prevent hearing impairment or disorders are disclosed. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to limit the present application.

The utility model relates to the technical field of hearing aid, specifically relates to an ear hanging type hearing aid, including main part assembly and the microphone assembly of setting in the both ends of main part assembly, the microphone assembly is indirectly connected in main part assembly through connection assembly and ear hanging assembly in proper order, at least one connection between main part assembly, ear hanging assembly, connection assembly and microphone assembly is detachable connection. The utility model sets up the connection between the main part assembly, ear hanging assembly, connection assembly and microphone assembly of ear hanging type hearing aid as detachable connection to be able to dismantle and replace one or more components when needing, for example, replace the microphone assembly of different power to adapt to the crowd of different hearing impairment degree, for example, replace the ear hanging assembly of different shape to adapt to the ear back structure of different human body.