The invention relates to a soundproof door framework, and in particular relates to a detachable soundproof door framework. The detachable soundproof door framework is composed of a support framework, a fixed sealed module, a detachable seal module and a lock body with a plug pin, wherein the support framework is welded by square steel or angle steel to form a rectangular framework, and the inner side of the support framework is welded on the edge frame of the door framework; the outer side of the support framework extends into a building wall of a door opening; the fixed sealed module is composed of a concave curve surface panel, a fixed module end surface panel and a fixed module arc panel and is welded integrally with the support framework; the detachable sealed module is composed of an inner side plate, a convex curve surface plate, a detachable module end surface panel and a detachable module arc panel and welded integrally; and the detachable sealed module is locked tightly with the door framework after being inserted into the fixed sealed module, and a test wire cable can be installed into the round opening of the detachable soundproof door framework, thereby reaching the aims that structure is compact, detaching is convenient, appearance is beautiful, and sealing soundproofness are achieved. The detachable soundproof door framework provided by the invention can be widely applied to engine laboratories and other acoustic testing rooms which need to replace testing wire cables.