Radioisotope generator and method of construction thereof

Abstract

An apparatus for producing a fluid containing a radioactive component, comprising a shielded chamber (5) having an opening for receiving an isotope container (6) containing a radioactive isotope (7); a chamber a chamber closure (18) for cooperating with and sealing the chamber opening; a first fluid port including a first hollow needle protruding from the chamber closure to the shielded in the chamber for fluid communication with the isotope chamber; a second fluid port including a second hollow needle protruding from the closed end of the chamber opposite the chamber closure to the shielded chamber in fluid communication with the isotope container; first and second compressible buffers (28, 29) mounted so as to at least partially surround the respective first and second hollow needles (12, 13) , each buffer member providing an outer surface in contact with the opposite end of the isotope container; and a spacer member of a predetermined thickness associated with one or each of the first and second compressible buffer members for Determine the positioning of the isotope container within the shielded chamber.

Description

technical field [0001] The present invention relates to technetium-99m ( 99m Tc) is a commonly used type of radioisotope generator and relates to a method of constituting the radioisotope generator. Background technique [0002] The diagnosis and / or treatment of disease in nuclear medicine is one of the main applications of short-lived radioisotopes. It has been confirmed that in nuclear medicine more than 90% of the diagnoses performed each year worldwide use 99m Tc as labeled radiopharmaceutical. Because radiopharmaceuticals have short half-lives, it is helpful to have on-site equipment to generate suitable radioisotopes. Therefore, the ratio of portable hospital size / clinical size has increased substantially in recent years 99m Use of the Tc generator. A portable radioisotope generator is used to obtain a shorter-lived daughter radioisotope, which is the product of radioactive decay of the longer-lived parent radioisotope, which is usually adsorbed on the bed of an i...

AI Technical Summary

Problems solved by technology

Although no information is provided about the structure of the generator, it is clear that a shield must be constructed around the ion exchange column, since it is essential that the channels in the shield be aligned precisely with the inlet and outlet of the ion exchange column

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