11results about How to "Ensure sterility" patented technology

The invention discloses a clindamycin phosphate vaginal gel preparation device and method, and belongs to the technical field of pharmacy. The method comprises the steps that after clindamycin phosphate vaginal gel is prepared by a preparation tank, the clindamycin phosphate vaginal gel is filled into a vacuum defoaming tank through a feeding opening in the bottom of the vacuum defoaming tank, and a packaging tank is conveyed to a rotary positioning mechanism through a conveying mechanism; and the filling mechanism is used for filling the clindamycin phosphate vaginal gel stored in the vacuum defoaming tank into the packaging tank on the rotary positioning mechanism. The invention aims to solve the problems that the existing clindamycin phosphate vaginal gel is complex in preparation process and difficult to carry out constant temperature control, the preparation and filling process needs to be transferred for multiple times, the viscosity of the gel can change along with time, temperature or storage conditions, the uniformity of the gel and the use experience of a patient are influenced, and the gel is difficult to be used. And the filled finished product gel is very easy to have a large number of bubbles, so that a more transparent and uniform gel product can be obtained, and the physical property and the use comfort of the gel are improved.

The utility model discloses an isolator based on a separated hydrogen peroxide evaporation conveying system, and relates to the technical field of pharmacy. Comprising a vaporized hydrogen peroxide generator, a conveying pipeline, a static pressure cabin and an operation cabin, the static pressure cabin and the operation cabin are arranged in an isolator box body, the vaporized hydrogen peroxide generator is communicated with the static pressure cabin through the conveying pipeline, and the static pressure cabin is communicated with the operation cabin through a circulating filter. The vaporized hydrogen peroxide generator comprises a storage and weighing system, a hydrogen peroxide evaporation system and a high-efficiency filter which are communicated in sequence, the storage and weighing system is used for storing and metering liquid hydrogen peroxide, and the hydrogen peroxide evaporation system is used for heating and vaporizing the liquid hydrogen peroxide; feeding into the static pressure cabin through a high-efficiency filter and a conveying pipeline; by designing the separated hydrogen peroxide evaporation conveying system, the equipment size and sanitation dead angles are reduced, and the pollution risk of a hydrogen peroxide evaporation device to a clean area is reduced.

The invention provides a slow-release injection containing levosalbutamol and a preparation process thereof, the injection combines a ginkgo leaf extract, a resveratrol extract, vitamin B6, vitamin C, tea polyphenol and other auxiliary components, and through specific preparation steps, the injection can be prepared into the slow-release injection containing levosalbutamol. Comprising the following steps: preparing raw materials, mixing and dissolving, preparing a slow-release carrier, adjusting pH, filtering, filling, sterilizing and the like, thereby obtaining the injection with the slow-release effect. Wherein the ginkgo biloba extract and the resveratrol extract are obtained through specific extraction and purification steps, and the activity and purity of the ginkgo biloba extract and the resveratrol extract are ensured. Polylactic acid-glycolide (PLGA) is used as a sustained-release carrier material and is combined with the active component to form a stable sustained-release system. Every 20 ml of the injection contains 0.2-1 mg of levosalbutamol, and the injection is suitable for a treatment scene where the drug concentration needs to be maintained for a long time. The injection is simple and controllable in preparation process, the obtained product is good in stability and remarkable in slow release effect, and a new choice is provided for treatment of respiratory tract obstructive diseases.

This utility model relates to the field of plastic packaging technology and discloses a secondary-sealing packaging box, comprising: a box body, the box body having a receiving cavity for accommodating syringes, filter needles, injection needles, and vials; the opening of the box body has a primary sealing area and a secondary sealing area, the primary sealing area corresponding to the area within the receiving cavity for accommodating syringes, filter needles, and injection needles, and the secondary sealing area corresponding to the area within the receiving cavity for accommodating vials; the primary sealing area and the secondary sealing area are independent of each other, allowing the sealing film to first cover and seal the primary sealing area, while the secondary sealing area remains open and is resealed by the sealing film after the vials are inserted. This utility model forwards the most cumbersome instrument sorting and assembly process to the instrument supplier, requiring the pharmaceutical factory to only perform the secondary sealing step, effectively solving the problem of the need for additional assembly work by pharmaceutical factories.

The utility model relates to the technical field of cell culture, and specifically discloses an online sterile filtering device for cell culture medium, which comprises: a liquid preparation mechanism; a filtering mechanism, which comprises a first filter and a second filter, the first filter is connected to the liquid preparation mechanism through a first pipeline, the first filter is connected to the second filter through a second pipeline, the second filter is externally connected to a third pipeline, and the first filter and the second filter are provided with filter cores; the third pipeline is connected to a first reactor; a functional mechanism, which comprises a steam pipeline connected to the first pipeline; and a control mechanism connected to the liquid preparation mechanism, the first filter, the second filter and the steam pipeline. The utility model realizes complete sterility of the second filter, and overcomes the defects of pollution hazards and incomplete cleaning in the online filtering of the cell culture medium in the prior art.

The invention discloses a medical disposable self-adhesive dressing and a manufacturing method thereof, which relates to the technical field of medical self-adhesive dressings, and comprises a self-adhesive dressing base layer, wherein a drug injection module and a drug storage module are installed inside the self-adhesive dressing base layer, wherein the drug injection module comprises a medical silicone injection layer installed inside the self-adhesive dressing base layer, wherein a medical silicone injection protective layer is installed at the bottom of the medical silicone injection layer, wherein a connecting cover is installed at the bottom of the self-adhesive dressing base layer, wherein a movable cover is installed at one side of the connecting cover, and wherein a peeling label is installed at one end of the movable cover. The present invention is provided with a drug injection module, wherein the drug injection module comprises a self-adhesive dressing base layer, a medical silicone injection layer, a medical silicone injection protective layer, a connecting cover, a movable cover, a peeling label and a re-adhesive coating, and wherein the built-in medical silicone injection layer allows drugs to be directly and accurately injected into the medical disposable self-adhesive dressing, thereby solving the problems of inconvenient drug administration and high infection risk during wound care for patients.

This invention relates to the field of medical device technology, and particularly to a centrifuge adapted for the preparation of centrifuge tubes for clinical cell mitochondrial extraction. The centrifuge includes: a centrifuge body, a centrifuge lid hinged to one side of the centrifuge body, a platelet detection device fixedly disposed on the side of the centrifuge lid away from the centrifuge body, and a liquid aspiration device rotatably disposed on the side of the centrifuge lid near the centrifuge body. A lid locking mechanism is fixedly disposed on the side of the centrifuge body near the centrifuge lid, and a locking hook is fixedly disposed on the side of the centrifuge lid near the centrifuge body, the locking hook matching the lid locking mechanism. This invention avoids the variability caused by human operation during multiple supernatant extractions, reduces the possibility of contamination from human operation, ensures the sterility and component stability of the extraction process, and greatly improves the efficiency and success rate of mitochondrial extraction.

The invention discloses female antibacterial liquid containing a lucid ganoderma extract and a preparation method of the female antibacterial liquid. The female antibacterial liquid is prepared from the following raw materials in percentage by weight: 0.134% of parachlorometaxylenol, 1.1% of a radix sophorae flavescentis extract, 20% of a malt extract, 5% of the lucid ganoderma extract, 42% of a grape fruit extract, 24.52% of olive oil, 5% of simmondsia chinensis seed oil, 0.45% of zedoary turmeric oil, 1.5% of eucalyptus oil and 0.3% of borneol. The ganoderma lucidum extract is extracted by adopting a water extraction and alcohol precipitation method, and the content of ganoderma lucidum polysaccharide is not less than 20%; the grape fruit extract is extracted by adopting a supercritical carbon dioxide extraction technology; the sophora flavescens extract is extracted by adopting an ethanol extraction method, and the matrine content is not less than 0.5%. The invention has the advantages that: the anti-bacterial and nourishing effects are integrated, the anti-bacterial effect is improved and the nourishing and protecting effects of the product are enhanced by carefully selecting a plurality of natural plant extracts and optimizing the proportion, and the anti-bacterial and nourishing mask is suitable for being used on sensitive skin; meanwhile, the stability and the use experience of the product are ensured by the fine preparation process, and the overall stability and the safety of the product are improved.

The invention discloses a beauty injection with an anti-aging function and a preparation method thereof, and relates to the technical field of beauty injections. Comprising the following components in percentage by mass: 5-15% of a collagen accelerant, 5-15% of a humectant, 5-15% of an anti-inflammatory agent, 5-15% of a whitening agent, 5-15% of an antioxidant and the balance of a solvent, and the total mass of the collagen accelerant, the humectant, the anti-inflammatory agent, the whitening agent, the antioxidant and the solvent is 100%. 10-20% of a humectant; 7-18% of an anti-inflammatory agent; 3-12% of a whitening agent; 8-15% of an antioxidant; the collagen accelerant, the humectant, the anti-inflammatory agent, the whitening agent and the antioxidant specifically comprise N-acetyl-D-glucose, hyaluronic acid, peptide, oligopeptide-1, tadpole collagen, hyaluronic acid, a blue algae extract, a fructus cannabis extract, arbutin, vitamin C, coenzyme Q10, tea polyphenol and moringa seed oil. The stability and permeability of the active ingredients are improved, and the effectiveness and absorptivity of the medicine are enhanced.

The utility model provides a sterile sampler. The sterile sampler comprises a sampling tube, a placing cavity is formed in the sampling pipe, a lower top cover is arranged at the top end of the placing cavity, an assembling part is arranged at the bottom of the lower top cover, and the lower top cover is detachably connected with the sampling pipe through the assembling part; an upper top cover is further arranged on the lower top cover, placing holes are correspondingly formed in the upper top cover and the lower top cover in a penetrating mode, and the sampling assembly penetrates through the two sets of placing holes to be arranged in the placing cavity; a closing assembly is also arranged between the upper top cover and the lower top cover and is in contact with the sampling assembly. According to the sterile sampler, through the arrangement of the upper top cover, the lower top cover and the closing assembly, the sampling head and a placement cavity in the sampling pipe are effectively isolated from the external environment, pollution of external microorganisms is prevented, and the risk of sample pollution is reduced through the isolation design; meanwhile, the contact between the closing assembly and the sampling assembly further enhances the isolation effect, and the practicability and convenience of the sampler are improved.

The utility model provides a kind of self-cleaning pathological tissue material taking platform, including equipment component, equipment component is provided with water scraping subassembly, auxiliary assembly is provided on water scraping subassembly, linkage assembly is provided below auxiliary assembly, equipment component includes base, the upper end of base is fixedly connected with operation table plate, the left and right two inner walls of operation table plate are symmetrically fixedly connected with multiple water outlets, the upper end right side of operation table plate is provided with water basin groove, water scraping subassembly includes strip groove being opened in the right inner wall of operation table plate, operation table plate is stably supported by the base in equipment component, left and right symmetrical water outlet and water basin groove form efficient cleaning system, can promptly discharge the waste liquid generated in the process of material taking, guarantee that operation table is dry and clean, maintain good working environment, and water scraping subassembly electric push rod drives water scraping strip plate to move, spring connection's triangular scraper is closely attached operation table plate, can quickly remove table area water, tissue debris and other sundries, significantly improve cleaning efficiency, reduce manual cleaning workload.