49 results about "Skin puncture" patented technology

The invention relates to a hand-held microneedling device (1; 20) for local puncturing of a skin, comprising a housing (2); a drive device which is arranged in the housing (2) and is configured to provide a drive force; a skin puncturing device (6); a microneedling puncturing tool (8) which is formed on the skin puncturing device (6) and is connected to the drive device such that, during operation, the microneedling puncturing tool (8) can be moved back and forth at a repetition rate by means of the drive force; and a needle plate (9) which is formed on the microneedling puncturing tool (8) and on which a plurality of puncturing needles (10) are arranged distributed over a front-side application surface (11); wherein, during operation, the microneedling puncturing tool (8) can be moved back and forth, between a front working position and a rear working position which is retracted in comparison thereto, by means of the drive force at the repetition rate. Furthermore, a skin puncturing device (6) for a hand-held microneedling device and an article are provided.

1. The name of the design product: disinfection cotton swab folding device. 2. The use of the design product: the design is used for disinfection cotton swab folding device, breaking independent packaging disinfection cotton swab, discarding the waste part, so as to reduce the skin puncture infection rate caused by secondary pollution of disinfection cotton swab. 3. The design points of the design product: in shape. 4. The picture or photo that can best show the design points: perspective drawing.

A system for accessing one or more artery in a head and neck area of a patient includes an access sheath including a tubular shaft having a distal end and a proximal end and a sheath lumen extending therethrough, the distal end of the shaft configured for placement through a puncture in skin and an adjacent arterial wall of a superficial temporal artery of a subject and to extend retrogradely within a portion of the superficial temporal artery of the subject, the proximal end of the shaft including a first connection portion, an intermediate portion of the sheath located between the distal end of the shaft and the proximal end of the shaft, the intermediate portion forming a curve of the sheath lumen, a resilient access-extension tube having an extension lumen extending therethrough, the extension lumen having a distal end and a proximal end, the distal end of the extension lumen configured to hydraulically couple to the sheath lumen at the first connection portion, and sealable opening carried by the access-extension tube and spaced from the distal end of the extension lumen, the sealable opening configured to allow insertion of an elongate medical device into the extension lumen for advancement through the extension lumen when the access-extension tube is coupled to the access sheath, for passage through the extension tube and the sheath lumen, and into the superficial temporal artery of the subject.

A card cutting tool effectively solves the problems that when a card is cut at present, the card is prone to displacement and inclination, and the right angle is prone to pricking the skin. Comprising a bottom plate, a sliding way is fixed to the rear side of the bottom plate, a sliding strip is slidably connected to the sliding way, a limiting mechanism is arranged on the sliding strip, the sliding strip is rotationally connected with two front-back opposite swing rods, a pressing plate is fixed to the lower ends of the two swing rods, a lower cutter is fixed to the right end of the bottom plate, and an upper cutter capable of being matched with the lower cutter is arranged on the right side of the bottom plate and can move up and down. The rear end of the upper cutter and the rear end of the lower cutter are both in a fillet shape, a plurality of scale grooves distributed in the left-right direction are formed in the upper surface of the sliding way, and numerical values are arranged on one sides of the scale grooves. The cutting device is ingenious in structure, convenient to use, simple in structure, easy to popularize and use, capable of preventing the problems of shifting or cutting inclination due to the fact that hands touch cards needing to be cut by mistake, capable of improving the cutting effect and improving the hand feeling during use and capable of avoiding skin puncturing.

The application discloses an integrated automatic blood-squeezing peripheral blood glucose detection device, which comprises a host computer (1) and a detachably connected disposable sterile integrated core (2). The disposable sterile integrated core (2) comprises a microneedle assembly (4), an elastic squeezing structure (3) arranged around the microneedle assembly (4), a blood glucose detection test paper (6), a capillary blood guiding channel (5) and an electrode contact (7). When the microneedle assembly (4) completes skin puncture, the elastic squeezing structure (3) applies synchronous micro mechanical squeezing force to the tissue around the blood sampling site, so that blood seeps out and is automatically transported to the blood glucose detection test paper (6) through the capillary blood guiding channel (5). The blood glucose detection test paper (6) is internally integrated in the disposable sterile integrated core (2), and the electrode contact (7) is used for electrical connection with the host computer (1). The application realizes the integration of blood sampling, automatic blood squeezing, blood guiding and detection by using a pure mechanical structure, and does not need manual blood squeezing and manual sample adding. The application has the advantages of simple structure, low cost, simple operation, safety and sanitation, and is suitable for rapid blood glucose detection in family and hospital scenes.

The invention belongs to the technical field of medical instruments, and particularly relates to a multifunctional beauty needle which comprises a syringe and a needle head, the needle head is detachably connected to the syringe, and two containing grooves are further formed in the syringe; the limiting mechanism is installed in the containing groove and used for limiting the puncture length of the needle head; the injection mechanism is mounted in the injection cylinder and is used for pushing out the medicament in the injection cylinder; the liquid pumping mechanism is also arranged in the syringe and is used for pumping the medicament; the guide rod is connected to the syringe; and the positioning mechanism is arranged on the guide rod and is used for limiting the moving stroke of the injection mechanism. By designing the limiting mechanism and the positioning mechanism, the skin puncturing depth of the needle head and the medicament injection amount can be accurately controlled. Different beautifying preparations can be injected into corresponding layers of the skin to achieve the best effect, and risks caused by too deep or too shallow injection are avoided.

The application relates to a puncture point adjusting and pressing device, and belongs to the technical field of hemostasis pressing devices. In order to solve the problems that the prior art cannot accurately press two puncture points, the pressing force cannot be self-adaptively adjusted according to the change of the blood vessel pressure, and the setting of the anti-pressure sore and sweat releasing structure leads to poor hemostasis pressing effect, poor comfort of patients and low practicability, the application provides a puncture point adjusting and pressing device which comprises a fixing belt and a contact base which is integrally formed with the fixing belt, a pressing mechanism is arranged on the contact base, the contact base is pressed to press and hemostasis the puncture points; specifically, the pressing mechanism is composed of a skin puncture point pressing assembly and a blood vessel pressure sensing assembly, the pressure of the blood vessel can be changed to self-adaptively adjust the pressing force of the skin puncture point and the blood vessel puncture point, so that the blood in the blood vessel can be normally transmitted, and the comfort of the patient during pressing is improved.

The utility model provides a multipurpose blood sampling assembly which comprises an injector, a three-way valve, an inspection test tube inserting piece, a puncture blood sampling piece and an indwelling catheter blood sampling piece, a first connecting end of the three-way valve is detachably connected with a nipple of the injector, and a second connecting end of the three-way valve is detachably connected with the indwelling catheter blood sampling piece. The indwelling catheter blood sampling piece is detachably connected with the puncture blood sampling piece, the third connecting end of the three-way valve is detachably connected with the inspection test tube insertion piece, and the inspection test tube insertion piece is detachably connected with an external inspection test tube. According to the multipurpose blood sampling assembly, blood sampling through the indwelling catheter end can be achieved while blood sampling through a skin puncture blood vessel is achieved, communication between every two channels of the three-way valve is achieved by adjusting the three-way valve, and then corresponding front section blood collection and test blood collection and storage are achieved; the catheter is prevented from being repeatedly disassembled and connected in the blood sampling process, and the blood sampling convenience and safety are improved.

This invention belongs to the technical field of medical materials and discloses a core-shell microneedle patch with anti-inflammatory and cartilage-protective functions, its preparation method, and its application. Method: 1) Prepare psoralen-loaded nanoparticles Mi@PSO; 2) Prepare a shell solution by mixing methacryloyl hyaluronic acid, HPA, and a photoinitiator; prepare a core solution by mixing HA and Mi@PSO; add the shell solution to the needle cavity of a microneedle mold and perform ultraviolet cross-linking to form the shell layer; add the core solution to the interior of the shell layer to form the core layer; add a hyaluronic acid solution to the mold, dry to form a backing layer, and demold to obtain a core-shell microneedle patch with anti-inflammatory and cartilage-protective functions. The microneedle patch of this invention has a regular needle morphology, a clear core-shell layered structure, good mechanical properties and skin puncture ability, and stable continuous release behavior; achieving inflammation regulation and cartilage protection. The microneedle patch of this invention is used to prepare products for the local treatment of rheumatoid arthritis.

1. The name of the design product: interventional catheter. 2. The use of the design product: the design product is used for interventional vascular operation. Through the guidance of imaging equipment (such as DSA, CT or ultrasound), the specially designed catheter is accurately sent into the target blood vessel or lesion site through the skin puncture blood vessel channel. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.

The present application relates to a kind of soluble microneedle patch of semaglutide peptide and its preparation method and purposes.The soluble microneedle patch of semaglutide peptide includes drug-loaded needle tip layer and back plate layer;Wherein, the drug-loaded needle tip layer includes semaglutide and needle tip layer matrix material;With the total weight of the drug-loaded needle tip layer 100% as 100%, the weight percentage of semaglutide is 85%~99%, and the weight percentage of the needle tip layer matrix material is 1%~15%.The needle type of the soluble microneedle patch of semaglutide is excellent, and the mechanical strength and skin puncture performance are superior, and the safety is high, and drug release and penetration rate are fast, and drug penetration rate is high, with excellent drug utilization and bioavailability;Its preparation method is simple, and controllability is good, and it is suitable for large-scale production.In addition, the soluble microneedle patch of semaglutide is convenient and fast, and patient compliance is high, with wide clinical application prospect.

This utility model belongs to the field of medical auxiliary device technology, specifically an internal auxiliary traction device for endoscopic thyroid surgery. It includes two support arms and a limiting component. The rear ends of the two support arms are screwed together. The limiting component is located between the two support arms, with one end screwed to the middle of one support arm. The limiting component has multiple slots for fixing, and correspondingly, the other support arm has a locking slot that matches the slots. By engaging the locking slots in different slots on the limiting component, the two support arms maintain different opening angles. The outer side of the front end of each support arm has a contact portion for contacting the area requiring traction to expose the surgical field. The support arm also has a clearance opening to facilitate the movement of the limiting component and the folding of the device. The overall structure of this utility model is simple, foldable for easy storage, and does not require skin puncture, thus avoiding additional damage.

The present disclosure includes a microneedle array patch including a polymeric structure having an array of polymeric microneedles configured to puncture the skin of a subject and a pressure plate having an array of holes configured for collecting a biological fluid sample from each skin puncture site by the array of polymeric microneedles. In some instances, the array of holes is configured for insertion of the polymeric microneedles therethrough, such as where the polymeric microneedles are punctured into the skin of the subject, retracted from the skin back through the array of holes and pressure is applied to the pressure plate onto the skin surface to collect the biological fluid sample from each skin puncture site. Methods for using the microneedle array patch to collect a biological fluid sample (e.g., interstitial fluid) from a subject and kits having one or more of the patches are also described.

According to the preparation method of the chlorogenic acid-methotrexate soluble microneedle, chondroitin sulfate and a methyl vinyl ether-maleic anhydride copolymer are adopted as matrix materials, and the drug-loaded microneedle is prepared through a two-step centrifugation method. The length of a needle body of the prepared microneedle is about 500 microns, the microneedle has good mechanical strength and skin puncture performance, the microneedle can be basically dissolved within 2 hours, the average drug content of chlorogenic acid is 57.97 + / -1.76 mu g / tablet, and the average drug content of methotrexate is 56.32 + / -1.67 mu g / tablet. An in-vitro percutaneous penetration test shows that the 6-hour cumulative transdermal rate of chlorogenic acid reaches 93.96%, the 6-hour cumulative transdermal rate of methotrexate reaches 86.92%, which are respectively 22.1 times and 3.0 times that of a control solution group, so that the efficient percutaneous delivery of the medicine is realized. The microneedle is small in skin irritation, the skin barrier can be naturally repaired within 15 minutes after puncture, and a new administration approach is provided for treatment of skin diseases such as psoriasis.

The application discloses a kind of microneedles, the microneedle includes first component, second component and water, wherein, first component is organic acid, second component is amino acid and / or active peptide, wherein, the mass ratio of first component and second component is 0.2-2:1;The mass percentage of injectable water is 0.05-5%, and the elastic modulus of the microneedle is greater than 1Gpa.The microneedle of the application has good forming rate, high hardness of needle tip, high skin puncture rate, can effectively improve the transdermal efficacy of active ingredients such as cosmetic peptides, and the soluble microneedle can be suitable for various skin, mucosa infectious diseases and medical beauty skin care.

The present invention discloses a radiofrequency wave puncture needle. When the knife shell is aligned with the skin incision and gently pressed downward, the skin resistance pushes the knife shell to compress the elastic movable mechanism, causing the knife body to extend out of the knife shell, and making the second ends of the first electrode body and the second electrode body come into contact to generate a first control instruction. The controller controls the radiofrequency wave generator to emit radiofrequency waves through the knife body to ablate skin cells; when the knife body completely cuts through the skin and enters the body, the thrust generated by the compression deformation of the elastic movable mechanism causes the knife shell to move away from the first electrode body and the second electrode body, so that the second ends of the first electrode body and the second electrode body are separated to generate a second control instruction, and the controller controls the radiofrequency wave generator to stop emitting radiofrequency waves. Therefore, the present invention only needs to press on the skin with a small force to perform skin puncture, which can not only achieve precise puncture, but also avoid damaging tissues and blood vessels.

The utility model relates to medical instrument technical field especially is a puncture training device for intravenous anesthesia, the utility model discloses a high simulation arm model, blood vessel simulation mechanism and puncture simulation mechanism, the inside surface of simulation subcutaneous soft tissue cover is opened along its length direction and is passed through the passage that can supply blood vessel simulation mechanism to pass, blood vessel simulation mechanism includes the simulation blood vessel section below skin puncture piece in the passage, a pair of respectively detachable type is established in the both sides of simulation blood vessel section and is communicated with simulation blood vessel section's communication pipe, is established in one of communication pipe and is used to inject simulation blood in the liquid inlet of communication pipe and is established between two communication pipes and is used to realize the blood pump of simulation blood circulation between simulation blood vessel section and communication pipe, the device solves the problem that simulation blood vessel cannot be replaced after using the prior art device.

The invention provides an external fixation traction device for traumatic orthopedics, and belongs to the technical field of medical instruments. The device comprises at least two fixing rings, restraining grooves are formed in the fixing rings, a connecting rod is installed between the fixing rings and located in the restraining grooves, a needle base is fixedly connected to the outer side of the connecting rod, and a kirschner wire is slidably connected into the needle base; and the compression assembly is used for compressing and fixing skin tissues around the puncture position of the kirschner wire, and the compression assembly is connected with the kirschner wire. By arranging the compression assembly which can be additionally arranged at any position of the kirschner wire, auxiliary pressing and fixing can be carried out on the skin around the kirschner wire puncture part, by means of the design, the skin can be effectively prevented from being pulled by the kirschner wire in the walking process of a patient, the risks of inflammation and infection at the skin puncture part are remarkably reduced, and the patient can feel comfortable. The problem that the Kirschner wire pulls the skin when a patient walks and exercises due to the fact that the contact position of the Kirschner wire and the skin is not protected in place is practically solved.

This invention provides an acupuncture point embedding device, comprising: a housing; a first motor disposed within the housing; a swing assembly comprising: a second motor, an electric telescopic rod, and a hinge, the second motor being disposed at the drive end of the first motor and connected to the hinge via the electric telescopic rod; an inner cylinder, the upper part of which is rotatably connected to the hinge, an electromagnet being disposed on the inner cylinder and detachably connected to the hinge; a vertical drive assembly disposed within the inner cylinder, the vertical drive assembly comprising a needle tube and a pusher, the needle tube and the pusher being detachably connected, the vertical drive assembly being used to drive the needle tube and the pusher to move vertically respectively; and an electrically controlled turntable disposed on the vertical drive assembly, the electrically controlled turntable having multiple through holes for accommodating thread bodies, the electrically controlled turntable being disposed on the docking path of the needle tube and the pusher. Thus, after a single skin puncture, the needle tube can be precisely tilted in any direction, and multiple threads can be automatically and continuously embedded.

The invention discloses a soluble traditional Chinese medicine thumbtack needle based on sodium hyaluronate and a preparation method and application of the soluble traditional Chinese medicine thumbtack needle based on sodium hyaluronate. The soluble traditional Chinese medicine thumbtack needle mainly comprises sodium hyaluronate, and the molecular weight range of the sodium hyaluronate is 10 kDa to 500 kDa; the length of the needle body is 0.5-2 mm, and the diameter of the needle tip is smaller than 100 microns; the needle body is conical or pyramid-shaped, the needle body contains medicines or functional components, the needle body adopts an ultra-short length design of 0.5-2mm, the diameter of the needle tip is less than 100 microns, and the needle body is conical / pyramid-shaped to optimize a puncture angle, so that mechanical stimulation during skin puncture is remarkably reduced, painless or slight pain treatment experience is realized, and compared with a traditional metal acupuncture needle or thumbtack needle, the needle body has the advantages that the needle body is simple in structure and convenient to use. The device is simple in structure and convenient to use, the fear of a patient to acupuncture is greatly reduced, the device is particularly suitable for children, old people and people terrorist of acupuncture, comfort and compliance in the treatment process are fundamentally improved, operation of professional medical staff is not needed, and the patient can complete acupuncture point application according to an instruction book by himself / herself.

The present disclosure relates to a capillary blood collecting device which includes a fixing device including an accommodating cavity for accommodating a blood collection finger and a squeezing member for squeezing blood to a fingertip site. The capillary blood collecting device is configured to detachably accommodate at least one skin puncture part on a blood collection side of the finger, and the skin puncture part includes a blood lancet that may be driven to puncture the blood collection finger, such that a sufficient amount of capillary blood quickly flows out from the capillary blood converged at the fingertip under the action of blood lancet.

1. The name of the design product: blood sampling pen. 2. The use of the design product: skin puncture device, such as blood sampling for blood testing. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 1 perspective view. 5. Design 1 is designated as the basic design.

A five-bevel needle tube, comprising a multi-bevel tip provided with one first bevel, two second bevels, and two third bevels. The first bevel has a first inclination angle of 9°±2° relative to the central axis and a first rotation angle of 0°. The five-bevel needle tube is characterized in that: the two second bevels serve as main cutting surfaces extending from the base to the apex of the multi-bevel tip and are symmetrically arranged, intersecting at the apex to form a second edge line with a needle point; the second bevel has a second inclination angle of 12°±2° and a second rotation angle of 45°±5°; the two third bevels are located at the middle portion of the multi-bevel tip and are symmetrically arranged; each of the third bevels intersects with one second bevel to form a third edge line, with the third bevel positioned on the lateral side of the second bevel. The third bevel has a third inclination angle of 11°±2° and a third rotation angle of 70°±5°. The described solution improves upon existing five-bevel needle tips, minimizing pain sensation during skin puncture by the needle tip.

The present disclosure relates to a medical device for supporting a catheter during a vascular procedure. The medical device comprises a bottom surface in contact with patient's body surface and a top surface supporting the catheter. The top surface forms an inclined plane or a ramp with the top-bottom connection area / line facing an access site or a skin puncture point of the catheter. The top surface may further comprise a groove to stabilize and guide the catheter during the vascular procedure.

The embodiment of the invention provides a simulation acupuncture point stimulation auxiliary device, and relates to the field of acupuncture training. The simulation acupuncture point stimulation auxiliary device comprises an acupuncture tensioning assembly, a frame fixing assembly, a supporting arm assembly and a needle penetrating assembly, a human body template and a mold plate can imitate a human body, the mold plate can form different skin area forms according to a guide lamp part, and when the tensioning degree of an imitated skin acupuncture point penetrating part is adjusted, the human body can be simulated. Only the air pump part needs to be used for punching the interior of the imitation leather hole-penetrating part, and the imitation leather hole-penetrating part is extruded and shrunk; the rolling hole needle body is inserted into the imitation leather hole penetrating part, the insertion and extraction force of the hole penetrating needle body can be detected under the action of the force transmission part, the force sensing part and the magnetic conduction part, the needle feeding depth of an operator is obtained according to the obtained data and the contraction state of the imitation leather hole penetrating part, the needle feeding depth data is compared with pre-recorded needle feeding data, and the needle feeding depth of the operator is determined. Therefore, the operator can conveniently and reasonably adjust the operation method of the operator.

This invention relates to a combined patellar fracture fixation device, comprising a Kirschner wire with threads at both ends, a tail cap, and a two-hole steel plate. The threaded Kirschner wire has a sharp end and a flat end, with an unthreaded middle section. The tail cap has a central channel connecting both ends of the Kirschner wire, with the thinner end embedded in the patellar bone. The two-hole steel plate has different widths at both ends; the wider end has a hole that connects to the tail cap, while the narrower end has a hole through which a tension band cable can pass. The Kirschner wire, tail cap, and steel plate are combined to form a patellar fracture fixation device, used in pairs. Connecting the cable creates a tension band for fixation. This invention offers better stability than traditional Kirschner wire tension band technology, effectively reducing the likelihood of loosening and displacement of the traditional Kirschner wire, the risk of cable slippage leading to tension band failure, and reducing the risk of irritation to surrounding tissues and skin puncture by the tail of the traditional Kirschner wire. This facilitates early postoperative functional exercises for patients, promotes patellar fracture healing, and provides a new and more effective fixation device for patellar fractures.

1. The name of the design product: blood taking needle head. 2. The use of the design product: installed in the automatic pressing blood taking needle, as the needle head for skin puncture. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: design 2 perspective view. 5. Design 2 is designated as the basic design.

The utility model relates to the technical field of beauty bars, and discloses an adjustable microneedle beauty bar which comprises a handle and microneedle bar bodies, the microneedle bar bodies are rotatably arranged on the handle, each microneedle bar body is formed by combining a shell, a microneedle plate and an adjusting assembly for adjusting the length of a microneedle, a plurality of microneedle bodies are arranged on the microneedle plate in an array mode, and the microneedle bodies are arranged on the shell. The shell is provided with through holes matched with needle bodies of the micro-needles, the micro-needle plates are symmetrically arranged on the two sides of the adjusting assembly, the adjusting assembly comprises a rotating shaft rotationally arranged in the shell, a plurality of rotating plates are arranged on the rotating shaft at equal intervals in an array mode, and two connecting plates are symmetrically arranged on the rotating plates with the rotating shaft as the center; one end of the connecting plate is hinged to the rotating plate, the microneedle plate is provided with connecting pieces with the same number as the rotating plate, and the other end of the connecting plate is hinged to the connecting pieces. According to the device, the extending length of the microneedle can be adjusted, the device is suitable for different skin areas and problems, and meanwhile it is ensured that the skin puncturing depth is consistent every time.

The invention discloses an IR783 soluble microneedle patch as well as a preparation method and application thereof, according to the method, chondroitin sulfate and a methyl vinyl ether-maleic anhydride copolymer are adopted as matrix materials, and a drug-loaded microneedle is prepared through a two-step pouring method. The length of the prepared microneedle body is about 500 microns, the diameter of the base is about 281 microns, and the microneedle has good mechanical strength and skin puncture performance and can be completely dissolved within 2 hours. The average drug loading capacity of IR783 is increased along with increase of the preparation concentration, and when the preparation concentration is 4 mg / mL, the average drug loading capacity reaches 28.51 + / -0.8013 microgram / tablet. An in-vitro release rate test shows that the release rate of IR783 within 15 minutes reaches 88.39%. A photo-thermal property investigation result shows that under the irradiation of 808nm laser, the photo-thermal temperature of IR783-DMNs can reach 56.77 DEG C to the maximum within 120 seconds, and exceeds a 42 DEG C threshold value required by photo-thermal therapy. The microneedle is non-irritant to the skin, the skin can be naturally healed within 15 minutes after puncture, and a new administration mode is provided for photothermal therapy of skin cancer.

The low-pain skin puncture device comprises a tubular outer cylinder, an ejection assembly and a rotary gear shifting sleeve, the ejection assembly and the rotary gear shifting sleeve are axially arranged in the tubular outer cylinder, a refill sleeve of the ejection assembly is clamped and fixed to the tubular outer cylinder, a trigger pressing piece is pressed to release a cantilever, and a refill rod can be limited in the tubular outer cylinder and axially controlled to eject. A protruding block on an elastic piece of the rotary gear shifting sleeve and a groove in the inner wall of the tubular outer barrel are rotationally positioned, and a step limiting structure on the rotary gear shifting sleeve is matched with an adjusting protrusion on the pen refill rod to limit the ejection stroke of the pen refill rod. The structure is simpler, the number of parts is only two thirds of that of an existing product, the product stability is better, low-pain blood sampling is achieved, assembling is more facilitated, the material cost is reduced, and the labor cost is also reduced.