Ambroxol injection and preparation method thereof
A technology for injections and ambroxol, which is applied in the field of ambroxol injections and its preparation, can solve problems affecting drug quality, poor stability, and difficulties, and achieve the effects of ensuring drug quality, strong buffer capacity, and ensuring sterility
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Embodiment 1
[0028]
[0029] Weigh disodium hydrogen phosphate and citric acid, add appropriate amount of water for injection to dissolve; add ambroxol hydrochloride, stir to dissolve; add sodium chloride to dissolve. Add 0.3% (W / V) activated carbon, stir for 20 minutes, and filter. Filled with nitrogen and sealed in 2ml brown glass ampoule. Sterilize and test for leaks (121°C, 15 minutes), and check for visible foreign matter, and the product is ready.
Embodiment 2
[0031]
[0032] Weigh disodium hydrogen phosphate and citric acid, add appropriate amount of water for injection to dissolve; add ambroxol hydrochloride, stir to dissolve; add sodium chloride to dissolve. Add 0.3% (W / V) activated carbon, stir for 20 minutes, and filter. Filled with nitrogen and sealed in 2ml brown glass ampoule. Sterilize and test for leaks (121°C, 15 minutes), and check for visible foreign matter, and the product is ready.
Embodiment 3
[0034]
[0035]Weigh disodium hydrogen phosphate and citric acid, add appropriate amount of water for injection to dissolve; add ambroxol hydrochloride, stir to dissolve; add sodium chloride to dissolve. Add 0.3% (W / V) activated carbon, stir for 20 minutes, and filter. Filled with nitrogen and sealed in 2ml brown glass ampoule. Sterilize and test for leaks (121°C, 15 minutes), and check for visible foreign matter, and the product is ready.
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