Small interference RNA molecule (SiRNA) capable of effectively killing and wounding tumour cell pointed at PLK1 mRNA, its mixture and use
Patent Information
- Authority / Receiving Office
- CN · China
- Current Assignee / Owner
- 杭州新瑞佳生物医药技术开发有限公司
- Publication Date
- 2005-08-10
- Estimated Expiration
- Not applicable · inactive patent
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Abstract
Description
technical field
[0001] The invention relates to the field of nucleic acid technology, in particular to a small interfering ribonucleic acid molecule (SiRNA) targeting PLK1 mRNA for effectively killing tumor cells, a mixture thereof and applications thereof. Background technique
[0002] Malignant tumor is a major disease that endangers human life and health, but so far there is still no effective treatment for it. Scientists have long been trying to develop new drugs that can effectively treat malignant tumors. Contents of the invention
[0003] The technical problem to be solved by the present invention is to provide a small interfering ribonucleic acid molecule (SiRNA) targeting PLK1 mRNA that can effectively kill tumor cells as an active ingredient of an antitumor drug. For this reason, the present invention adopts the following technical solutions: it is a double-stranded RNA molecule and its nucleotide sequence has at...