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Pearl powder soft capsule

A pearl powder and soft capsule technology, which is applied in the directions of capsule delivery, medical raw materials derived from mollusks, metabolic diseases, etc., can solve the problems such as MCT that have not yet been seen, achieve easy preparation and pill pressing, improve fluidity, and reduce volume. Effect

Active Publication Date: 2005-10-19
FERGUSON WUHAN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But so far there is no record that MCT is used in the production of pearl powder soft capsules

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Pearl powder soft capsule, it is made up of pearl powder, caprylic glyceride and beeswax, and the share weight of each component is:

[0019] Pearl Powder (Zhejiang Zhuji Yuecui Pharmaceutical Co., Ltd.) 3000g

[0020] Soy salad oil 1518g

[0021] Glyceryl Caprylate 332g

[0022] Beeswax (Hebei Dongguang Pharmaceutical Packaging Material Factory) 47.5g.

[0023] The preparation method of above-mentioned pearl powder soft capsule comprises the following steps: 1). By weight: pearl powder 3000g, glyceryl caprylate 332g, soybean salad oil 1518g, beeswax 47.5g, choose pearl powder, glyceryl caprylate, Soybean salad oil, beeswax; 2). Take glyceryl caprylate, soybean salad oil, and beeswax, heat and melt to make an oil-wax mixture; 3). Add the oil-wax mixture to pearl powder, stir evenly, pass through a colloid mill or Homogenizer, then vacuum degassing; according to the existing soft capsule production process of transfer mode, 10,000 soft capsules are made, and the pearl...

Embodiment 2

[0025] Compound pearl powder soft capsule, which is composed of pearl powder, vitamin E, caprylic acid glyceride, soybean salad oil and beeswax, and the weight of each component is:

[0026] Pearl Powder (Zhejiang Zhuji Yuecui Pharmaceutical Co., Ltd.) 3000g

[0027] Vitamin E (BASF company) 200g

[0028] Soy salad oil 1204g

[0029] Glyceryl Caprylate 360g

[0030] Beeswax (Hebei Dongguang Pharmaceutical Packaging Material Factory) 36g.

[0031] The preparation method of above-mentioned compound pearl powder soft capsule comprises the following steps: 1). By weight: pearl powder 3000g, vitamin E 200g, glyceryl capricate 360g, soybean salad oil 1204g, beeswax 36g, choose pearl powder, vitamin E , soybean salad oil, caprylic capric acid glyceride, beeswax; 2). Take pearl powder, add vitamin E to make a mixture; 3). Take caprylic capric acid glyceride, soybean salad oil, beeswax, heat and melt, and make oil Wax mixture; 4). Add the oil-wax mixture into the mixture, stir even...

Embodiment 3

[0033] Compound pearl powder soft capsule, which is composed of pearl powder, vitamin E, corn oil, caprylic acid glyceride and beeswax, and the weight of each component is:

[0034] Pearl powder (Zhejiang Zhuji Yuecui Pharmaceutical Co., Ltd.) 3000g,

[0035] Vitamin E (BASF company) 500g,

[0036] Corn oil (commercially available, Wuhan Zhongchang Vegetable Oil Co., Ltd.) 625g,

[0037] Glyceryl Caprylate 471g,

[0038] Beeswax (Hebei Dongguang Pharmaceutical Packaging Material Factory) 19.4g.

[0039] The preparation method of above-mentioned compound pearl powder soft capsule comprises the following steps: 1). By weight: pearl powder 3000g, vitamin E 500g, corn oil 625g, caprylic acid glyceride 471g, beeswax 19.4g, choose pearl powder, vitamin E , corn oil, glyceryl caprylate, beeswax; 2). Take pearl powder, add vitamin E to make a mixture; 3). Take glyceryl caprylate, corn oil, beeswax, heat and melt to make a mixture of oil and wax ; 4). Add the oil-wax mixture into t...

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Abstract

The soft pearl powder capsule includes pearl powder and characterized glyceryl octyl caprate in the amount of 4-39 wt%. The addition of medium carbon chain glyceryl octyl caprate can lower the viscosity of the material and improve the flowability of material so as to facilitate the preparation of the soft capsule. The soft pearl powder capsule may have pearl powder content as high as 60 %, and this reduces the size of the soft capsule and is favorable to make best use of pearl powder.

Description

technical field [0001] The invention relates to a pearl powder soft capsule whose high dry solids are pearl powder. Background technique [0002] Soft capsule preparation workers all hope to make the capsule as small as possible, so that the user swallows as little as possible of substances irrelevant to the purpose of use, and makes swallowing, transportation, and storage more convenient. When the content of dry solids is high (such as pearl powder), the production often encounters difficulties due to the viscosity of the material. The solution is usually to crush the material to a sufficient fineness; screen the appropriate suspending agent to reduce the amount of suspending agent; discharge the air bubbles brought in during the preparation process; when the above methods are ineffective, the amount of diluent has to be increased , The composition is divided into more units, which increases the workload of production, increases the cost of production and production, and b...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/48A61K35/618A61P3/02A61P25/20A61P37/02
Inventor 梁庆钧刘健王宁
Owner FERGUSON WUHAN BIOTECH
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