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Preparation containing compound gentamicin procaine

A technology of gentamicin and procaine, which is applied in the field of dosage forms for the treatment of stomach diseases, can solve the problems of unsatisfactory medication needs and single dosage forms, and achieve the effects of rich drug varieties, high compliance, and convenient taking and carrying

Inactive Publication Date: 2005-12-28
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prescription of the medicine is reasonable and the curative effect is remarkable, but the dosage form is single, which is far from meeting people's medication needs.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Take gentamicin sulfate 10 million units, procaine hydrochloride 50 grams, vitamin B 12 0.01 g pulverized / ultrafinely pulverized into fine powder for later use; another appropriate amount of excipients was mixed with the above fine powder, packed into capsules to obtain 1000 capsules of compound gentamicin and procaine.

Embodiment 2

[0023] Get 100 million units of gentamicin sulfate and 500 grams of procaine hydrochloride to pulverize / superfinely pulverize into fine powder for subsequent use; vitamin B 12 0.3 g is dissolved in appropriate amount of ethanol for later use; the above-mentioned fine powder and appropriate amount of auxiliary materials and the above-mentioned vitamin B 12 The ethanol solution was mixed evenly, granulated, dried, and packed into capsules to obtain 1000 capsules of compound gentamicin and procaine.

Embodiment 3

[0025] Get 20 million units of gentamicin sulfate and 100 grams of procaine hydrochloride to pulverize / superfinely pulverize into fine powder for subsequent use; vitamin B 12 0.02 g is dissolved in appropriate amount of ethanol for later use; the above-mentioned fine powder and appropriate amount of auxiliary materials and the above-mentioned vitamin B 12 The ethanol solution was mixed, made into pellets, and packed into capsules to obtain 1000 capsules of compound gentamicin and procaine.

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PUM

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Abstract

A compound gentoomycin procaine in the form of slow-release tablet, release-controlled tablet, dispersing tablet, chewing tablet, micropills, dropping pills, capsule or softgel for treating gastrosis is prepared.

Description

technical field [0001] The invention relates to a dosage form containing compound gentamicin and procaine for treating stomach diseases. Background technique [0002] Stomach disease is common disease and frequently-occurring disease, brings a lot of misery to the patient, has a strong impact on people's health. Compound gentamicin procaine preparation consists of gentamicin sulfate, procaine hydrochloride, vitamin B 12 and appropriate amount of auxiliary materials, among which gentamicin sulfate has antibacterial effect on various Gram-negative bacteria, Gram-positive bacteria and Helicobacter pylori, procaine hydrochloride has the effect of local anesthesia, vitamin B 12 It is an essential substance for the formation of normal epithelial cells in the digestive tract. The combination of the three can play the role of antibacterial, pain relief and promoting gastric mucosal repair. The currently used dosage forms are compound gentamicin and procaine granules, which have be...

Claims

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Application Information

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IPC IPC(8): A61K31/7036
Inventor 毛友昌毛晓敏
Owner 毛友昌
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