Preparation containing compound gentamicin procaine

A technology of gentamicin and procaine, which is applied in the field of dosage forms for the treatment of stomach diseases, can solve the problems of unsatisfactory medication needs and single dosage forms, and achieve the effects of rich drug varieties, high compliance, and convenient taking and carrying

Inactive Publication Date: 2005-12-28
毛友昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prescription of the medicine is reasonable and the curative effect is remarkable

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0020] Example 1:

[0021] Take 10 million units of gentamicin sulfate, 50 grams of procaine hydrochloride, vitamin B 12 0.01 g is crushed / ultrafinely crushed into fine powder for use; another appropriate amount of auxiliary materials is taken and fully mixed with the above-mentioned fine powder, and then packed into capsules to obtain 1000 capsules of compound gentamycin procaine.

Example Embodiment

[0022] Example 2:

[0023] Take 100 million units of gentamicin sulfate and 500 g of procaine hydrochloride and pulverize / ultrafinely pulverize them into fine powder for later use; vitamin B 12 0.3 g is dissolved in appropriate amount of ethanol for later use; the above-mentioned fine powder and appropriate amount of excipients and the above-mentioned vitamin B 12 The ethanol solution was mixed, granulated, dried, and encapsulated to obtain 1,000 compound gentamicin procaine capsules.

Example Embodiment

[0024] Example 3:

[0025] Take 20 million units of gentamicin sulfate and 100 g of procaine hydrochloride and pulverize / ultrafinely pulverize them into fine powder for later use; vitamin B 12 0.02 g is dissolved in an appropriate amount of ethanol for use; the above-mentioned fine powder and appropriate amount of auxiliary materials and the above-mentioned vitamin B 12 The ethanol solution was mixed to make pellets and encapsulated to obtain 1000 capsules of compound gentamicin procaine.

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PUM

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Abstract

A compound gentoomycin procaine in the form of slow-release tablet, release-controlled tablet, dispersing tablet, chewing tablet, micropills, dropping pills, capsule or softgel for treating gastrosis is prepared.

Description

technical field [0001] The invention relates to a dosage form containing compound gentamicin and procaine for treating stomach diseases. Background technique [0002] Stomach disease is common disease and frequently-occurring disease, brings a lot of misery to the patient, has a strong impact on people's health. Compound gentamicin procaine preparation consists of gentamicin sulfate, procaine hydrochloride, vitamin B 12 and appropriate amount of auxiliary materials, among which gentamicin sulfate has antibacterial effect on various Gram-negative bacteria, Gram-positive bacteria and Helicobacter pylori, procaine hydrochloride has the effect of local anesthesia, vitamin B 12 It is an essential substance for the formation of normal epithelial cells in the digestive tract. The combination of the three can play the role of antibacterial, pain relief and promoting gastric mucosal repair. The currently used dosage forms are compound gentamicin and procaine granules, which have be...

Claims

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Application Information

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IPC IPC(8): A61K31/7036
Inventor 毛友昌毛晓敏
Owner 毛友昌
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