Dragon's blood vaginal effervescent tablet and its preparing method

A technology for effervescent tablets and blood jellyfish, which is applied in medical formulas, medical preparations containing active ingredients, drug delivery, etc. It can solve problems such as inaccurate dosage and drug waste, and achieve advanced technology, improved accuracy, and enhanced curative effect Effect

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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a bloody vaginal effervescent tablet preparation with convenient use and accurate dosage and a preparation method thereof, so as to solve the problem of treating gynecological diseases under the prior art, such as cervical erosion, uterine fibroids, adnexal cysts, dysfunctional uterine bleeding, Menorrhagia, gynecological inflammation such as pelvic inflammatory disease, adnexitis, etc. There is no suitable vaginal medication, and difficulties such as inaccurate dosage and drug waste

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] prescription:

[0060] Dried blood 200g

[0061] Lactose 78g

[0062] Citric acid 150g

[0063] Sodium bicarbonate 100g

[0064] Magnesium Stearate 12g

[0065] Micronized silica gel 10g

[0066] A total of 1000 pieces were made

[0067] Preparation:

[0068] First, the above-mentioned materials were crushed through a 100-mesh sieve, and the dried blood, lactose, citric acid, sodium bicarbonate, magnesium stearate, and micropowdered silica gel were fully mixed and evenly controlled, and the humidity of the environment was controlled below 45%. The tablet pressing method is pressed into Xuejie vaginal effervescent tablet.

Embodiment 2

[0070] prescription:

[0071] Dried blood 150g

[0072] Tartaric acid 220g

[0073] Sodium bicarbonate 140g

[0074] Cross-linked sodium carboxymethyl starch 16.5g

[0075] Talc powder 7.5g

[0076] Proper amount of absolute ethanol solution

[0077] A total of 1000 pieces were made

[0078] Preparation:

[0079] First, crush the above-mentioned materials through a 100-mesh sieve, fully mix the dried blood, tartaric acid, sodium bicarbonate, and cross-linked carboxymethyl starch sodium, add an appropriate amount of ethanol to make a soft material, and granulate with a 16-mesh sieve , after drying at 60°C for 1.5 to 2.5 hours, sieve the granules with a 16-mesh sieve, add lubricant talcum powder, mix well, and press to make Xuejie vaginal effervescent tablets.

Embodiment 3

[0081] prescription:

[0082] Dried blood 200g

[0083] Microcrystalline Cellulose 110g

[0084] 60g pregelatinized starch

[0085] Citric acid 120g

[0086] Sodium bicarbonate 90g

[0087] Sodium carbonate 10g

[0088] Magnesium Lauryl Sulfate 5g

[0089] Starch slurry 5g (calculated as starch)

[0090] A total of 1000 pieces were made

[0091] Preparation:

[0092] First, crush the above-mentioned materials through a 100-mesh sieve, fully mix the dried blood, part of the microcrystalline cellulose, pregelatinized starch, and citric acid, and then add an appropriate amount of starch slurry to make soft materials into 20-mesh sieves for granulation. After drying at 60°C for 2 to 4 hours, granulate with a 16-mesh sieve and set aside; take another sodium bicarbonate, sodium carbonate, and the remaining microcrystalline cellulose, mix them evenly, and prepare granules with the previous method; mix the two granules, and add After the magnesium lauryl sulfate is mixed even...

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PUM

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Abstract

The present invention relates to a kind of viginal effervescent dragoní»s blood tablet, which is prepared with dragoní»s blood in effective dosage as main medicine, acid and alkali disintegrating agent and other supplementary material, and through tabletting directly or after pelletizing or coating. The effervescent dragoní»s blood tablet has acid and alkali disintegrating agent capable of generating CO2 gas after reacting with water, and thus can foam and disintegrate inside vagina for dragoní»s blood to disperse fast inside vagina. It is used in treating pelvic inflammatory disease, uterine appendages cyst, cervicitis, vaginitis, hysteromyoma and other womení»s diseases.

Description

technical field [0001] The present invention relates to a novel pharmaceutical preparation, in particular to a bloody vaginal effervescent tablet for treating gynecological diseases such as pelvic inflammatory disease, adnexal cyst, cervicitis, vaginitis, cervical erosion, uterine fibroids, and gynecological diseases. its preparation method. Background technique [0002] Dracaena, also known as Qilin Drain, has been used as a precious traditional Chinese medicine for more than 1,500 years in my country. plant. Dried blood has the effects of reducing stasis and relieving pain, hemostasis and promoting granulation, and is used for traumatic injuries, internal injuries and bruises, and traumatic hemorrhage. Usually, it is ground or put into pills and taken orally, or ground and sprinkled or put into plasters for external use. [0003] Blood jelly single dose and compound formula have been widely used in gynecological diseases, such as cervical erosion, uterine fibroids, adnex...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/20A61K9/46A61P15/02A61P15/00
Inventor 严轶东刘鸿林
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