Eye-drops prepns. contg. tetrandrine and its application for preparing medicine therewith

A technology of tetrandrine and ophthalmic preparations, which are applied in the application field of ophthalmic preparations

Inactive Publication Date: 2006-06-14
胡世兴 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] There is no report on the application of ophthalmic preparations containing tetrandrine at home and abroad

Method used

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Examples

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Embodiment Construction

[0061] A preparation method of an ophthalmic preparation containing tetrandrine. Its tetrandrine powder eye drops are by dissolving 1g of tetrandrine powder in 10-20ml of 0.25mol hydrochloric acid to obtain tetrandrine hydrochloride, which is used as a reserve; levofloxacin hydrochloride 3g, dissolved in water for injection at 50-70℃, then add 1g sodium metabisulfite, 0.3 disodium edetate and 6.3g sodium chloride and stir, after cooling, mix with tetrandrine hydrochloride, add injection Make up to 1000ml with water, mix well, filter, sterilize with 90-110°C circulating steam for 30-40 minutes, separate, check and pack.

[0062] A preparation method of an ophthalmic preparation containing tetrandrine, in which tetrandrine powder is used in eye drops by dissolving 1g of tetrandrine powder with 10-20ml of 0.25mol hydrochloric acid to obtain powdered tetrandrine hydrochloride for use; 3g of dexamethasone, 0.3g of chlorhexidine, and 0.05g of borneol were dissolved in water for injectio...

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Abstract

An eye medicine containing tetrandrine for treating ophthalmitis, allergic ophthalmopathy, glaucoma, catarart, etc is prepared from tetrandrine (0.001-2 Wt%), other medicines (0-5), and excipient (93-99.999).

Description

Technical field [0001] The invention relates to a pharmaceutical preparation containing organic active ingredients of isoquinoline derivatives, in particular to an ophthalmic preparation containing tetrandrine and its application in preparing an ophthalmic preparation containing tetrandrine for treating ophthalmic diseases. Background technique [0002] In the pathogenesis of ophthalmopathy, inflammation is the main pathophysiological process of most ophthalmopathy, and it has become the main determinant of the prognosis of the disease. Controlling inflammation is an important principle in the treatment of eye diseases. Therefore, inflammation inhibitors are the most commonly used drugs by ophthalmologists in order to effectively control the progress of eye diseases and prevent patients from ultimately causing blindness. [0003] After cataract extraction, inflammation often occurs due to the destruction of blood humor and other factors, and it usually takes a long time to recove...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/5383A61K9/00A61K31/4748A61K45/06A61P27/02
Inventor 胡世兴徐彦贵
Owner 胡世兴
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