Kangweisu granular preparation and its preparation method

A granule preparation, kangweisu technology, applied in the field of medicine, can solve the problems of difficult preparation of granules, complicated process screening, etc., and achieve the effects of strong compliance, good taste, and strong hygroscopicity

Inactive Publication Date: 2006-08-30
CSPC OUYI PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the strong hygroscopicity of kangweisu, the process of screening is complicated during the preparation process, and the preparation of granules is difficult, so there is still no production and use of granule dosage forms.

Method used

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  • Kangweisu granular preparation and its preparation method

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Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0015] Aiming at the problem of kangweisu's strong hygroscopicity and difficulty in preparing granular dosage forms, the present invention carried out a series of tests on different proportions of main ingredients and auxiliary materials. The test results are shown in Table 1:

[0016] Table 1: Selection table of main and auxiliary materials for prescription

[0017]

[0018] Prescription four

Kangweisu

110g

Lactose 745g

Mannitol 150g

(Mannitol

150g)

Aspartame 6g

4% HPMC water soluble

130g of liquid

The preparation is easy, the granules are easy to dry, and the mouth

Feel better, the particle solubility check is not

Great.

Prescription five

Kangweisu

100g

Lactose 745g

Mannitol 150g

(Mannitol

150g)

Aspartame 6g

8% soluble lake

Powder solution

100g

The preparation is easy, the granules are easy to dry, and the mouth

It feels good, and the particle melting property is qualified.

...

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Abstract

A particle of bicarnesine with low hydroscopicity and agreeable taste is prepared from bicarnesine, filler, adhesive, wetting agent and flavouring proportionally. Its preparing process is also disclosed.

Description

Technical field [0001] The invention relates to a pharmaceutical preparation and a preparation method, in particular to a Kangweisu granule preparation for treating gastrointestinal diseases such as digestive organ dysfunction and its preparation, and belongs to the technical field of medicine. Background technique [0002] Kangweisu is also called vitamin BT and carnitine. Its main component is DL-carnitine hydrochloride, which is a medicine that helps digestion. The molecular structure of Kangweisu is: C 7 H 15 O 3 NHCL. In nature, the organism itself contains this substance. It can promote the secretion of digestive juice, enhance the activity of digestive enzymes and intestinal function. It can be used clinically to treat abdominal fullness, nausea, belching, and senile digestion caused by dysfunction of digestive organs. Adverse complications, infants and young children anorexia, high temperature environment and gastrointestinal dysfunction caused by pregnancy. Since Kangwei...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/205A61K9/16A61P1/14
Inventor 高志峰魏树辉郭卫芹智彩辉
Owner CSPC OUYI PHARM CO LTD
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