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Traditional Chinese medicine extract for treating gastroenteritis and traditional Chinese medicine composition containing same

A technology of extracts and compositions, applied in the field of traditional Chinese medicine compositions containing the active extracts, can solve the problems of poor controllability of quality standards, lack of innovation in technology, and unacceptable problems

Inactive Publication Date: 2006-10-11
HAINAN MEDICAL COLLEGE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these products have the disadvantages of unclear effective substances and poor controllability of quality standards, which make it difficult to meet the requirements of "safe, effective, controllable, and stable" for traditional Chinese medicine.
At present, although there are a variety of dosage forms to facilitate the use of patients, this type of preparation is only a simple dosage form conversion, there is no innovation in technology, and its mechanism of action cannot be revealed by scientific methods, so it is difficult to be accepted by the international market

Method used

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  • Traditional Chinese medicine extract for treating gastroenteritis and traditional Chinese medicine composition containing same
  • Traditional Chinese medicine extract for treating gastroenteritis and traditional Chinese medicine composition containing same
  • Traditional Chinese medicine extract for treating gastroenteritis and traditional Chinese medicine composition containing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] The preparation example of the Chinese medicine extract of embodiment 1 Auranthus japonica, Polygonum punctatus

[0082] According to the ratio of 2:1, a total of 6800 grams of maple and Polygonum japonica were taken, combined and decocted for extraction 3 times, the amount of water added each time was 9.5 times the amount of medicinal materials, and the extraction time was 2 hours, 1.5 hours, and 1.0 hour respectively. The extracts were combined and filtered, the filtrate was concentrated under reduced pressure, left to cool for 6 hours, centrifuged (3000r / h), and the supernatant was concentrated under reduced pressure to obtain 1072 grams of the crude extract (A); the crude extract ( A) Carry out AB-8 type macroporous adsorption resin chromatography, first use 14 times of water as the eluent to elute, then concentrate and dry the water eluate to obtain 680 grams of water-eluted fraction (AA); after that Carry out elution with the 60%-95% alcohol of 21 times amount aga...

Embodiment 2

[0083] The preparation of embodiment 2 Chinese medicine composition powder of the present invention

[0084] Grind the Chinese medicine extract prepared in Example 1 into a fine powder, sieve, take 1 part of the sifted Chinese medicine extract fine powder, add 3.5 parts of starch, 6.5 parts of lactose powder and mix in equal amounts Evenly, the powder is obtained by dividing doses according to the volume method.

Embodiment 3

[0085] The preparation of embodiment 3 Chinese medicine composition hard capsules of the present invention

[0086] Pulverize the Chinese medicine extract prepared in Example 1, pass through a 60-100 mesh sieve, take 1 part of the fine powder of the Chinese medicine extract that has been sieved, add 1.1 parts of dry starch as a filler, and add 1-3% talcum powder Used as a glidant, mixed evenly and then filled with hollow capsules to obtain hard capsules.

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Abstract

The invention relates to a Chinese medicinal extract for treating acute and chronic enteritis, its preparing process and Chinese medicine compositions containing the active extract, which is prepared from Daphniphyllum calycinum Benth and Polygonum hydropiper Linn. The composition can be prepared into any oral administration preparations suitable for treating stomach and intestinal diseases.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract with therapeutic activity for acute and chronic gastroenteritis, a preparation method thereof, and a traditional Chinese medicine composition containing the active extract, belonging to the field of traditional Chinese medicine. Background technique [0002] Daphniphyllumcalycinum Benth. is Daphniphyllumcalycinum Benth., which is a plant of Daphniphyllumcalycinum Benth. It is used as medicine with Daphniphyllumcalycinum Benth. The nature and flavor are pungent, bitter, cool, and have the effects of clearing away heat and detoxification, promoting blood circulation and relaxing tendons. [0003] Polygonum hydropiper L. is a Polygonum hydropiper L. of the family Polygonaceae, and it is used as medicine with the whole herb. Nature and flavor are pungent, warm, tool expelling wind and promoting diuresis, dissipating blood stasis and relieving pain, detoxification and detumescence, effect of k...

Claims

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Application Information

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IPC IPC(8): A61K36/70A61K31/7048A61P1/04C07B63/00C07D311/30C07H17/07
Inventor 刘明生靳德军陈德梅张俊清王元国郭小明刘红雨康胜利符乃光
Owner HAINAN MEDICAL COLLEGE
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