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Medicine composition for treating pain and preparing method therefor

A composition and drug technology, applied in the direction of drug combination, testing of drug preparations, pharmaceutical formulations, etc., can solve problems such as rare drugs

Active Publication Date: 2006-10-25
CHENGDE TRADITIONAL CHINESE MEDICINE GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

According to incomplete statistics, nearly 200 kinds of oral and external preparations for the treatment of lumbago and leg pain have been included in the national standards, but there are few drugs that have both oral and external preparations in the same drug combination

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0098] Embodiment 1: rubber ointment is prepared as follows

[0099] Take 316g of Nuxychia, 84g of Ground Beetle, 84g of Sichuan Achyranthes, 84g of Ephedra, 84g of Vinegar-made Frankincense, 84g of Vinegar-made Myrrh, 84g of Bran-fried Silkworm, 84g of Bran-fried Atractylodes, 84g of Scorpion, and 84g of Licorice. Seed powder: get 316g of Nuxychnium, be ground into fine powder, measure strychnine content 1.7% according to the method under the content determination item of the Pharmacopoeia of the People's Republic of China, then add starch 177g, make strychnine C 21 h 22 N 2 o 2 After the content is calculated as 1.09% by dry product, mix well to obtain about 493g of modulated nux.

[0100] Add 390g of 10% starch slurry to prepare Nuxyche seed powder, make granules, and dry; take the above granules, use 60% ethanol as solvent, carry out percolation, collect the filtrate, reclaim ethanol, concentrate under reduced pressure until the relative density is 80°C. The thick past...

Embodiment 2

[0101] Embodiment 2: rubber ointment is prepared as follows

[0102] 480g of prepared Nuxyche powder, 84g of ground beetle, 84g of Achyranthes sichuanensis, 84g of ephedra, 84g of vinegar-made frankincense, 84g of vinegar-made myrrh, 84g of bran-fried silkworm, 84g of bran-fried herb, 84g of scorpion, 84g of licorice, and 385g of 10% starch slurry added to the prepared nuxyche powder , made into granules, and dried; take the above granules, use 60% ethanol as a solvent, carry out percolation, collect the filtrate, recover ethanol, and concentrate under reduced pressure to a thick paste with a relative density of 1.30 to 1.35 at 80°C for subsequent use. The remaining ground beetles and other nine flavors were crushed and extracted with 90% ethanol under reflux for 3 times, each time for 2 hours, the extracts were combined, filtered, and the filtrate was concentrated to a clear paste with a relative density of 1.15-1.20 at 60°C. Combine with the above thick paste, add 3.0 to 3.4...

Embodiment 3

[0103] Embodiment 3: the preparation of granule

[0104]460g of prepared nuxe seed powder, 84g of ground beetle, 143g of Sichuan Achyranthes bidentata, 86g of ephedra, 140g of vinegar-made frankincense, 82g of vinegar-made myrrh, 145g of bran-fried silkworm, 84g of bran-fried atractylodes, 139g of scorpion, 84g of licorice, and the above ten flavors. % starch slurry 385g, made into granules, and dried; take the above granules, use 60% ethanol as solvent, carry out percolation, collect the filtrate, recover ethanol, concentrate under reduced pressure to a thick paste with a relative density of 1.30-1.35 at 80°C for later use . The remaining ground beetles and other nine flavors were crushed and extracted with 90% ethanol under reflux for 3 times, each time for 2 hours, the extracts were combined, filtered, and the filtrate was concentrated to a clear paste with a relative density of 1.15-1.20 at 60°C. Combine with the above thick paste, add conventional auxiliary materials to ...

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PUM

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Abstract

The present invention relates to a Chinese medicine composition for curing pain and preparation method of its preparation. Said Chinese medicine composition is composed of 10 Chinese medicinal materials of nux vomica, wingless cockroach, cyathula root, ephedra, frankincense, myrrh and others. Besides, said invention also provides its quality control method.

Description

field of invention [0001] The invention relates to a pharmaceutical composition, a preparation method and a quality control method thereof, in particular to a pharmaceutical composition for treating pain, a preparation method and a quality control method thereof. Background technique [0002] Lumbago and leg pain is a kind of common disease, frequently-occurring disease, and the traditional Chinese medical science is attributed to it as arthralgia. Pain is the main clinical symptom that these diseases cause physical and mental pain and life inconvenience to patients. According to incomplete statistics, nearly 200 kinds of oral and external preparations for the treatment of lumbago and leg pain have been included in the national standards, but there are few drugs that have both oral and external preparations in the same drug combination. Contents of the invention [0003] The purpose of the present invention is to provide a preparation method of a pharmaceutical compositio...

Claims

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Application Information

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IPC IPC(8): A61K36/56A61K9/00A61K35/64A61K35/646A61P29/00G01N30/02G01N30/90G01N33/15
Inventor 索伟庞永清秦婷王春民李沈明计福全
Owner CHENGDE TRADITIONAL CHINESE MEDICINE GROUP
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