Prescription of herba fibraureae recisae preparation

A technology of palmetine and preparations, which can be used in pharmaceutical formulations, antifungal agents, and resistance to vector-borne diseases, etc., and can solve problems such as toxic side effects, drug resistance, and non-reduction

Inactive Publication Date: 2007-01-17
曹明成
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0011] Modern medicine mostly uses antibacterial drugs for treatment. In recent years, although new antibiotics have come out continuously, they have not reduced the incidence and recurrence of gynecological inflammation, bacill

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0061] (1) Specifications, prescription and preparation method of palmatine for injection

[0062] Specification: 20mg

[0063] prescription:

[0064] Palmatine hydrochloride (calculated as palmatine hydrochloride) 20g

[0065] Mannitol 40g

[0066] Add water for injection to 2000ml

[0067] A total of 1000 bottles were made

[0068] Preparation:

[0069] Aseptic operation: Weigh mannitol according to the prescription, put it in a container, add 1600ml of water for injection, heat and stir to dissolve, then add the prescribed amount of palmitine, stir to dissolve, add an appropriate amount of 1M hydrochloric acid solution to adjust the pH value to 5.0, add Add water for injection to the full amount, add 0.05% (W / V) activated carbon, keep stirring at 40°C for 15 minutes, filter with filter paper, filter with No. 3 sand core funnel, and filter the drug solution through 0.45 μm and 0.22 μm filter membranes in a sterile room Sterilize. After measuring the content and pH val...

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PUM

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Abstract

A medicine in the form of injection for treating gynecologic inflammation, bacillary dysentery, enteritis, the infection of respiratory tract and urinary tract, surgical infection, conjunctivitis, etc by intravenous injection is prepared from fibrauretin, mannitol or glucose or sodium chloride, and the water for injection.

Description

Technical field: [0001] The invention relates to a prescription of a new traditional Chinese medicine preparation and a preparation method thereof, more specifically, a prescription and a preparation method in which palmatine (calculated as palmatine hydrochloride) is changed from intramuscular injection to intravenous drip administration . Background technique: [0002] 1. Source of prescription [0003] "Pautogenin for injection" is a modified route of administration and dosage form based on the variety "Pautogenin Injection" recorded on page 524 of the 1977 edition of "Chinese Pharmacopoeia" (Part One). [0004] 2. Set the topic [0005] Common gynecological inflammatory diseases include gynecological vulvitis, pelvic inflammatory disease, vaginitis, chronic cervicitis, endometritis, adnexitis, salpingitis, etc. In a woman's life, it is difficult not to be attacked by gynecological inflammation. According to the census of 20,911 women of childbearing age conducted by ...

Claims

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Application Information

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IPC IPC(8): A61K31/4375A61K47/10A61K47/26A61K9/08A61P15/02A61P31/10A61P31/04A61P13/02
CPCY02A50/30
Inventor 曹明成
Owner 曹明成
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