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Chinese-medicinal preparation for treating cardivascular and cerebrovascular diseases and its making method

A technology for cardiovascular and cerebrovascular diseases and traditional Chinese medicine preparations, which is applied in cardiovascular system diseases, blood diseases, pharmaceutical formulations, etc., and can solve the problems of incompletely proposed active ingredients of drugs, high prices, and low density of extracts.

Inactive Publication Date: 2007-01-17
GUIZHOU YIBAI PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the cardiovascular Chinese patent medicine market is large in scale, it is still dominated by large varieties, such as Compound Danshen Dripping Pills, Tongxinluo, Buchang Naoxintong, Di'ao Xinxuekang, Suxiao Jiuxin Pills, Shuxuening and Mailuoning, etc. In the scale of market sales, patent medicines have large brands and good dosage forms, but they are expensive, which makes most cardiovascular patients discouraged from taking them.
In addition, some drugs treat the symptoms but not the root cause, and some drugs are discontinued due to inaccurate curative effects during the application process.
And the existing Tongmai Oral Liquid extraction process is rough, for example, the extraction process of the Tongmai Oral Liquid with the number WS3-B-3980-98 published in the Ministry of Standards has the following deficiencies: the medicinal materials in this process are directly decocted without soaking. boiled, and the relative density of the extract is too low so that the active ingredients of the drug are not fully proposed; secondly, because diabetes and cardiovascular disease are closely related, and the oral liquid made by the original method contains sucrose, it is not suitable for those with cardiovascular disease. Patients with diabetes complications

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Prescription: Salvia 500g, Chuanxiong 500g, Pueraria 500g, cyclamate 5g, potassium sorbate 2.5g

[0060] Preparation method: add the above three flavors, add 8 times the water to soak for 6 hours, decoct twice, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, and the relative density of the filtrate is 1.08 when the filtrate is concentrated to 60°C. After filtration, the filtrate was concentrated at low temperature to a clear paste with a relative density of 1.39 at 60°C. Add cyclamate, potassium sorbate, and distilled water to adjust the total amount to 1000ml, stir well, refrigerate and let stand for 12 hours, filter, fill in 10ml vials in a sterile or semi-sterile state, a total of 100 bottles, seal, and sterilize, that is Get oral solution.

Embodiment 2

[0062] Prescription: Salvia 101g, Chuanxiong 101g, Pueraria 101g, cyclamate 5g, potassium sorbate 2.5g

[0063] Preparation method: add the above three flavors, add 8 times the water to soak for 6 hours, decoct twice, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, and the relative density of the filtrate is 1.08 when the filtrate is concentrated to 60°C. After filtration, the filtrate was concentrated at low temperature to a clear paste with a relative density of 1.39 at 60°C. Add cyclamate, potassium sorbate, and distilled water to adjust the total amount to 1000ml, stir well, refrigerate and let stand for 12 hours, filter, fill in 10ml vials in a sterile or semi-sterile state, a total of 100 bottles, seal, and sterilize, that is Get oral solution.

Embodiment 3

[0065] Prescription: Salvia 999g, Chuanxiong 999g, Pueraria 999g, cyclamate 5g, potassium sorbate 2.5g

[0066] Preparation method: add the above three flavors, add 8 times the water to soak for 6 hours, decoct twice, the first time is 1.5 hours, and the second time is 1 hour, combine the decoction, filter, and the relative density of the filtrate is 1.08 when the filtrate is concentrated to 60°C. After filtration, the filtrate was concentrated at low temperature to a clear paste with a relative density of 1.39 at 60°C. Add cyclamate, potassium sorbate, and distilled water to adjust the total amount to 1000ml, stir well, refrigerate and stand for 12 hours, filter, fill in 10ml vials in a sterile or semi-sterile state, a total of 100 bottles, seal, and sterilize. Oral solution, ready to use.

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PUM

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Abstract

A Chinese medicine 'Tongmai oral liquid' for treating cardiovascular and cerebrovascular diseases is prepared from red sage root, Chuan-xiong rhizome and pueraria root. Its preparing process is also disclosed.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine preparation for treating cardiovascular and cerebrovascular diseases and a preparation method thereof, in particular to Tongmai Oral Liquid and other medicinal preparations made from traditional Chinese medicines such as salvia miltiorrhiza, chuanxiong and kudzu root. technical background: [0002] Ischemic cardiovascular and cerebrovascular diseases mainly include coronary atherosclerotic heart disease (coronary heart disease), ischemic stroke, various angina pectoris and transient ischemic attack, and arteriosclerosis, cerebral thrombosis, angina pectoris, etc. Vascular system common diseases, frequently-occurring diseases. Due to my country's entry into an aging society, accelerated pace of life, and changes in dietary structure, the sales growth rate of cardiovascular and cerebrovascular drugs is higher than the world's growth rate. Statistics from the Ministry of Health show that from 2000 ...

Claims

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Application Information

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IPC IPC(8): A61K36/53A61P9/10A61P7/02
Inventor 王泽坤
Owner GUIZHOU YIBAI PHARMA CO LTD