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Confining positve and negative ions with fast oscillating electric potentials

A technology of oscillating potential and ions, which is used in the field of mass spectrometers to achieve the effect of high signal-to-noise ratio

Active Publication Date: 2007-02-07
THERMO FINNIGAN
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  • Claims
  • Application Information

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Problems solved by technology

However, conventional multipole trapping can only simultaneously confine particles whose mass / charge ratios do not differ by more than a factor of a few hundred

Method used

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  • Confining positve and negative ions with fast oscillating electric potentials
  • Confining positve and negative ions with fast oscillating electric potentials
  • Confining positve and negative ions with fast oscillating electric potentials

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Embodiment Construction

[0025] figure 1 Shown is a mass spectrometry system 100 that operates in accordance with one aspect of the invention. The system 100 includes a precursor ion donor 110, a 2D multipolar ion trap 120, a reagent ion donor 130, and a controller 140. The precursor ion donor 110 is used to generate ions, which includes precursor ions. The ions generated by the precursor ion donor 110 are implanted into the 2D multipolar ion trap 120. The reagent ion donor 130 generates ions including reagent ions. The ions generated by the reagent ion donor 130 are also injected into the 2D multipolar ion trap 120. The 2D multipolar ion trap 120 forms a channel, in which precursor ions and reagent ions are applied to different electrodes in the ion trap 120 by the controller 140, and the oscillation potential generated by the periodically changing voltages is limited in the radial and axial directions. In the channel.

[0026] The precursor ion donor 110 includes: one or more precursor ion sources 112...

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Abstract

Methods and apparatus for trapping or guiding ions. Ions are introduced into an ion trap or ion guide. The ion trap or ion guide includes a first set of electrodes and a second set of electrodes. The first and second sets of electrodes are arranged to define an ion channel to trap or guide the introduced ions. Periodic voltages are applied to electrodes in the first set of electrodes to generate a first oscillating electric potential that radially confines the ions in the ion channel, and periodic voltages are applied to electrodes in the second set of electrodes to generate a second oscillating electric potential that axially confines the ions in the ion channel.

Description

[0001] Cross-references to related applications [0002] This application claims the priority of a U.S. unlicensed patent application whose filing date is January 23, 2004, the application number is 10 / 764,435, and the title is "Confining Positive and Negative Ions with Fast Oscillation Electric Potentials", which is hereby incorporated by reference Full text application. Technical field [0003] The invention relates to a mass spectrometer. Background technique [0004] A mass spectrometer analyzes the mass of sample particles such as atoms, molecules, etc., and it usually includes an ion source, one or more mass analyzers, and one or more detectors. In the ion source, the sample particles are ionized. The sample particles can be ionized using a variety of techniques, such as chemical reactions, electrostatic forces, laser beams, electron beams, or other particle beams. These ions are transmitted to one or more mass analyzers so that they separate the particles based on their mas...

Claims

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Application Information

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IPC IPC(8): H01J49/42
CPCH01J49/063H01J49/0095H01J49/4225H01J49/0072
Inventor 约翰·E·P·西卡
Owner THERMO FINNIGAN
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